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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

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Cholera: Clinical features, diagnosis, treatment, and prevention

LaRocque, R.; S.B. Calderwood and A.Bloom UpToDate (2020) C1

The document provides a detailed overview of cholera, including its clinical features, diagnosis, treatment, and prevention. It explains the causes of cholera, its symptoms such as severe diarrhea and dehydration, and the importance of rehydration therapy (oral or intravenous) to reduce mortality. T... more

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Interim U.S. Guidance for Monitoring and Movement of Persons with Potential Ebola Virus Exposure

Centers for Disease Control and Prevention CDC (2014)

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Medicinal products under development for the treatment of Ebola

European Medicines Agency EMA (2014)

Interim Assessement Report The EMA review was started by the Agency’s Committee for Medicinal Products for Human Use (CHMP) to support decision-making by health authorities. This first interim report includes information on seven experimental medicines intended for the treatment of people infecte... more

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Field Guide for Preparedness and Response to Diphtheria Outbreaks in the Western Pacific Region

World Health Organization WHO (2023) C_WHO

Due to high routine vaccination coverage, overall counts of diphtheria case have significantly declined in the Western Pacific Region recently. However, diphtheria is still prevalent in several countries and areas of the Region and remains a public health issue due to its high case fatality rate. ... more

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Cervical Cancer Prevention and Control Policy (South Africa)

Dept. of Health, Republic of South Africa (2021) C1

Cervical cancer, along with maternal deaths, has been identified as a national priority in South Africa as well as other Sub-Saharan African countries. Cervical cancer is the second most common cancer among women in South Africa, after breast cancer. Due to limited access to prevention, early dia... more

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National Drug Information Service Training Course for Pharmacists. Participant's Manual

Ministry of Health, Federal Democratic Republic of Ethiopia (2018) CC

The Federal Ministry of Health (FMOH) has been coordinating sector wide reforms that aim to improve equity and quality of health services. It is widely known that; the sector is growing in line the overall growth and transformation plan of the country and the sector is bein... more

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The impact of climate change on mental health and emotional wellbeing: current evidence and implications for policy and practice

Lawrence, E.; R. Thompson, G. Fontana, et al. (2021) CC

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Interim Guidance: Gender Alert for COVID-19 Outbreak

Inter-Agency Standing Committee IASC, et al. (2020) C1

Recognizing the extent to which the COVID-19 outbreaks affects women and men differently is hugely important. Some preliminary data suggested that more men than women are dying, potentially due to sex-based immunological differences, higher rates of cardiovascular disease for men and lifestyle choic... more

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National Guidelines for the Management of Tuberculosis 2013-2017, 3rd ed.

Republic of the Gambia, Ministry of Health and Social Welfare, National LeprosyTB Control Programme (2012) C1

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Report of the fourth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination: virtual meeting, 1–3 June 2021

World Health Organization WHO (2021) C_WHO

Since 2000, concerted efforts by national programmes, supported by public–private partnerships, nongovernmental organizations, donors and academia under the auspices and coordination of the World Health Organization (WHO), have produced important achievements in the control of human African trypan... more

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Gambiense human African trypanosomiasis: the bumpy road to elimination

Hasker E, Hope A, Bottieau E. Wolters Kluwer Health, Inc. (2022) C2

Gambiense human African trypanosomiasis is a deadly infectious disease affecting West and Central Africa, South Sudan and Uganda, and transmitted between humans by tsetse flies. The disease has caused several major epidemics, the latest one in the 1990s. Thanks to recent innovations such as rapid di... more

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Young people and the law in Asia and the Pacific: a review of laws and policies affecting young people's access to sexual and reproductive health and HIV services

UNESCO Office Bangkok and Regional Bureau for Education in Asia and the Pacific United Nations Educational, Scientific and Cultural Education; UNFPA; UNAIDS; UNDP; Youth Lead (2013) C2

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Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations

Bernard M. Branson, S. Michele Owen, Laura G. Wesolowski et Centers for Disease control and Prevention (2014) C_CDC

This document updates recommendations for HIV testing by laboratories in the United States and offers approaches for reporting test results to persons ordering HIV tests and to public health authorities. The recommended algorithm is a sequence of tests used in combination to improve the accuracy of ... more

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Test procedures for insecticide resistance monitoring in malaria vector mosquitoes

World Health Organization WHO (2016) C_WHO

2nd edition. WHO's recommendation has not changed: the standard WHO susceptibility tests should remain a primary method by which resistance is detected. However, it was considered necessary to update the existing resistance-monitoring procedures to also highlight the need for operationally meaningfu... more

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Контекст психического здоровья. Свод методических рекомендаций по вопросам политики и оказания услуг в области психического здоровья

Всемирная организация здравоохранения Всемирная организация здравоохранения (2007) C_WHO

Свод методических рекомендаций по вопросам политики и оказания услуг в области психического здоровья. На долю психических расстройств приходится значительная ча... more

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National HIV & AIDS Strategic Plan 2016-2020. Abridged Version

Ministry of Health, Ghana, Ghana AIDS Commission (2016) C1

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Facing Alzheimer’s disease in the developing countries

Marciani, D.J. Rev Neuropsiquiatr (2017) C2

Enfrentando la enfermedad de Alzheimer en los países en desarrollo. Rev Neuropsiquiatr 80 (2), 2017 (P. 105-110) Recibido: 03/02/2017 Aceptado: 12/06/2017

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Management, control and prevention of tuberculosis - Guidelines for health care providers

Prof. C. Abobltins, L. Brown, Prof N. Curtis, et al. Department of Health & Human Services; State Goverment Victoria (2015) C2

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Research gaps and needs to optimize the use of assisted vaginal birth: technical brief

World Health Organisation (WHO) (2023) C_WHO

Lack of trained providers capable of identifying which labouring women could benefit from assisted vaginal birth (AVB), and of safely performing the procedure is a major barrier for its use. Education and training are, therefore, considered crucial for building skills and confidence in conducting AV... more