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Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV. What's New
recommended

ClinicalInfo. gov (2025) C_CDC
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations. The guidelines were updated to comply with Executive Orders
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Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV
recommended

ClinicalInfo. gov (2025) C_CDC
Full Guidelines
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Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV. Dosing Charts
recommended

ClinicalInfo. gov (2025) C_CDC
Dosing Recommendations for Prevention and Treatment
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Guidance on handling interruptions in antiretroviral treatment due to HIV service disruptions, drug shortages, or stockouts
recommended

World Health Organization WHO (2025) C_WHO
Questions and answers. A key priority is preventing the interruption of current HIV treatment and prevention medicines. This Q&A outlines advice when this is not possible. Available in Arabic, Chinese, English, French, Portuguese, Russian and Spanish
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WHO guidelines on the management of advanced HIV disease
recommended

World Health Organization WHO (2025) C_WHO
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
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Malawi Viral Load Standard Operating Procedure Manual Version

Ministry of Health, Malawi (2020) CC
The goal of producing these Standard Operating Procedures (SOPs) was therefore targeted at fostering standardization across all levels of care to ensure HIV viral load monitoring remains a basic right offered to all people living with HIV (PLHIV) on lifelong antiretroviral therapy (ART) regardless o ... more
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HIV - Elimination of mother-to-child transmission

United Nations International Children's Emergency Fund UNICEF (2025) C_UNICEF
Progress in reducing new HIV infections among children has stagnated in recent years
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African Plan Towards the Elimination Of New HIV Infections Among Children By 2025 and Keeping Their Mothers Alive

African Union (2023) CC
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access ... more
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Plan Africain Pour Éliminer La Transmission Verticale Des Nouvelles Infections Par Le VIH, La Syphilis Et Le Virus De L’hépatite B Chez Les Enfants D’ici 2030 Et Pour Maintenir Leurs Mères En Vie

African Union (2023) CC
Les piliers adoptés pour le plan AEVT sont les suivants : a) dépistage précoce chez les enfants exposés au VIH, à la syphilis et au VHB ; b) réduction des inégalités en matière de traitement chez les PBFW et les enfants exposés au VIH, à la syphilis et au VHB ; c) prévention des nouvelle ... more
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HIV prevention and undiagnosed infections in children in sub-Saharan Africa

Tassembedo, S.; et al. (2025) C1
The Lancet HIV Volume 12, Issue 6e459-e462June 2025
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HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies

Kay, A.W.; et al. (2022) CC
Pathogens 2022, 11, 33. https://doi.org/10.3390/pathogens11010033
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Characteristics and mortality of children living with HIV/TB coinfection in a tertiary hospital in a resource-limited setting

Prima Putra, S.; et al. (2025) CC
BMC Infectious Diseases Volume 25, article number 1289, (2025)
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Mental health challenges and HIV status disclosure among children and adolescents living with HIV in Eastern Uganda

Kirabira, J., Rukundo, G.Z., Atim, L. et al. (2025) CC
Nature Sci Rep 15, 35329 (2025). https://doi.org/10.1038/s41598-025-19261-7
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HIV Early Infant Diagnosis and Viral Load Point of Care Diagnostics: Market and Supply Update

United Nations International Children's Emergency Fund UNICEF (2020) C_UNICEF
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact ... more
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Algorithm for early infant diagnosis for HIV exposed children

FHI260; Ministry of Health Zambia (2024) CC
If baby HIV exposed, do DBS at six weeks or any time the child is seen if still below 12 months. If > 12 months, do HIV antibody test.
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Complete testing coverage for the early infant diagnosis algorithm and associated factors among infants exposed to HIV, Uganda, 2017–2019

Akunzirwe, R.; et al. (2025) CC
PLoS One 20(6): e0324338.https://doi.org/10.1371/journal.pone.0324338
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Overview of the POC EID Training Toolkit

United Nations International Children's Emergency Fund UNICEF (2023) C_UNICEF
Orientation slides for trainers
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Point of care EID training package
recommended

United Nations International Children's Emergency Fund UNICEF (2023) C_UNICEF
This training package provides materials to guide onsite training for the introduction of POC EID testing. The topics focus on what health workers at each facility need to learn in order to confidently begin POC EID high-quality testing; the package provides materials for both classroom and hands-on ... more
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Counseling Cards for Caregivers of HIV-Exposed Infants and other Orphans and Vulnerable Children

ICAP Global Health; Pepfar, USAID, et al. (2019) C1
These messages may be used as stand-alone resources, and also could be used as a supplement to The Essential Package, a comprehensive set of tools and guides for program managers and service providers supporting programs that address the unique needs and competencies of vulnerable children in a holi ... more
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HIV Treatment Adherence Counseling and Retention Guide. A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14)
recommended

Anderson, L.; J. Jospin, S. Safren, et al. FHI360 (2024) CC
A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14) in Orphans and Vulnerable Children (OVC) Programs