Background
Chronic congestive heart failure is a common condition that, if untreated, markedly impairs the quality of life and is associated with a high risk of recurrent hospitalization and death.
Methods
This review is based on articles retrieved by a selective search in PubMed, as well as on r...elevant guidelines.
Results
Evidence-based treatment options are available only for congestive heart failure with a low ejection fraction. Pharmacotherapy is based on neurohumoral inhibition of the renin-angiotensin-aldosterone system and the adrenergic system. The prognosis of patients with this condition has been further improved recently through the introduction of combined angiotensin receptor antagonists and neprilysin inhibitors. Modern implantable devices are a further component of treatment. Implantable defibrillators and special pacemakers for cardiac resynchronization are well established; the utility of alternative devices (baroreflex modulation or cardiac contractility modulation) needs to be investigated in further studies. It was recently shown that the catheter-based treatment of secondary mitral regurgitation with a MitraClip improves the outcome of selected patients.
Conclusion
The treatment of chronic systolic heart failure as recommended in the relevant guidelines, with drugs and implanted devices if indicated, can significantly improve the clinical outcome.
more
Updated Treatment Guidelines
In this report, we describe early childhood trauma and its effects, offer promising strategies for ECE programs and systems to help young children who have experienced trauma, and present recommendations for state policymakers and other stakeholders looking to support trauma-informed ECE for this vu...lnerable group.
more
The purpose of this article is to consider the relationshipbetween religion and healthcarein order to suggest how physicians and other health care providers shouldrespond when the faith-based preference of apatient clashes with the medically indicatedtreatment modalities.
Manual for use in primary care
Accessed 15th of October 2015
Introduction
Chapter A.13
Prevention, early identification, assessment and intervention in low- and middle-income countries | A Review | CHILD AND ADOLESCENT HEALTH AND DEVELOPMENT
This document provides guidance to host States on the vetting and registration of volunteers and volunteer organisations.
It also provides guidance to UN, NGO and other civil society actors on how they can support and complement State ef-forts through operational activities.
Providing improved water supply to low-income urban communities is a difficult challenge faced by water utilities throughout Africa and Asia.
This guide provides an introduction to available options for serving these communities.
The guide draws on sector experience in general, and more particular...ly on WSUP’s extensive experience of implementing urban WASH programmes in sub-Saharan Africa and elsewhere.
more