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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Global antimicrobial resistance and use surveillance system (‎GLASS)‎ report: 2022

World Health Organisation (WHO) (2022) C_WHO

The WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched in 2015 to foster AMR surveillance and inform strategies to contain AMR. The system started with surveillance of AMR in bacteria causing common human infections and has expanded its scope to include surveillance... more

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Effectiveness of a diabetes program based on digital health on capacity building and quality of care in type 2 diabetes: a pragmatic quasi-experimental study

Moreas Morelli, D.; Rubinstein, F.; Santero, M.; et al. BMC Health Services Research, part of Springer Nature (2023) CC2

Health systems in Latin America face many challenges in controlling the increasing burden of diabetes. Digital health interventions are a promise for the provision of care, especially in developing countries where mobile technology has a high penetration. This study evaluated the effectiveness of th... more

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The distinctive role of the Catholic Church in development and humanitarian response: 7 ways the Church makes a difference

Catholic Agency for Overseas Development CAFOD (2021) CC

7 Febr. 2021 As COVID-19 continues to wreak havoc in countries – decimating people’s livelihoods, and leaving health systems struggling to provide healthcare and vaccines for the entire population - governments and donors should look to the Church as a partner. The essential Church networks, tr... more

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WHO country cooperation strategy 2014-2018, Myanmar

World Health Organization (WHO), Country Office for Myanmar (2014) C_WHO

The strategic priorities of the CCS 2014–2018 are:
(1) Strengthening the health system.
(2) Enhancing the achievement of communicable disease control targets.
(3) Controlling the growth of the noncommunicable disease burden.
(4) Promoting health throughout the life course.
... more

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Africa, WASH, and the Millennium Development Goals: A Local Systems Case Study of How Senegal Achieved MDG Target 7c

McGahey, Christopher USAID (2017) C1

Nationally, Senegal met the MDG target for water supply access. It did this by engaging the public and private sectors to effectively invest and report on investments. It focused on larger population centers, less on remote regions of the country. Its achievements set the stage for more equitable an... more

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Core Indicators. Health Situation in the Americas, 2018

Pan American Health Organization (PAHO); Organización Panamericana de la Salud (2019) C_WHO

For the 24th consecutive year, PAHO has published the report Health Situation in the Americas: Core Indicators featuring the latest information on key indicators for the Region of the Americas. This 2018 edition includes data on the 82 core indicators for the countries, territories, and sub regions ... more

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Water, Sanitation and Hygiene Manual

Norwegian Refugee Council; et al. (2015) C1

WASH Training for Hygiene Promotion Staff. This manual has been designed to train NRC hygiene promotion incentive staff on ... concept and importance of hygiene, diseases that are present or a risk in Kakuma Refugee. Camp and how to prevent them; monitoring WASH activities and prevention, managemen... more

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Sexual Violence in Detention

International Committee of the Red Cross (ICRC) (2017) C1

We have long been working to prevent and end sexual violence in armed conflicts and to ensure that the countless victims – men, women, boys and girls – receive the help they need.
In this document, we examine sexual violence specifically in relation to people deprived of their liberty. We c... more

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Apercu des Besoins humanitaires 2016

l’Equipe Humanitaire Pays (2015) C2

le Sénégal continue d’être confronté à une crise alimentaire et nutritionnelle qui touche particulièrement le nord et l’est du pays. Selon les estimations faites en novembre 20151, plus de 2,4 millions de personnes sont en insécurité alimentaire (soit 17% de la population), dont 220 461 ... more

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Inclusion of Persons with Disabilities in Humanitarian Action
recommended

Inter-Agency Standing Committee IASC (2019) C1

Guidelines. The guidelines set out essential actions that humanitarian actors must take in order to effectively identify and respond to the needs and rights of persons with disabilities who are most at risk of being left behind in humanitarian settings. The recommended actions in each chapter pl... more

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Handbook for public health capacity-building at ground crossings and cross-border collaboration

World Health Organization WHO (2020) C1

This handbook follows a comprehensive approach to health system strengthening at borders in order to support IHR national focal points and other national agencies in developing and implementing evidence-based action plans for IHR capacity development at ground crossings. The approach includes the mo... more

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Urban Ecosystem-based Adaptation: Regreening Cities to Takle Climate Change

UN Enivronemnt Programme UNEP (2022) CC

Briefing Note 8. Ecosystem-based adaptation (EbA) is a strategy for adapting to the adverse impacts of climate change by harnessing nature and the services it can provide. This strategy is crucial for cities and peri-urban areas, threatened by a multitude of climate hazards and home to more than ha... more

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The Ministry of Health through the National AIDS Secretariat, has developed the Strategic Operational Plan for Condom Programming in Sierra Leone with a focus on reinvigorating condom use to ensure “u

Ministry of Health; National AIDS Secretariat; UNFPA; UNAIDS (2025) CC2

The Ministry of Health through the National AIDS Secretariat, has developed the Strategic Operational Plan for Condom Programming in Sierra Leone with a focus on reinvigorating condom use to ensure “uninterrupted access to male and female condoms and lubricants for Key Populations, young people an... more

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National Comprehensive HIV Prevention, Care, and Treatment Training for Pharmacy Professionals. Participant Manual

Ministry of Health, Federal Democratic Republic of Ethiopia Ministry of Health, Federal Democratic Republic of Ethiopia (2018) CC

In line with its decentralization principle, the Ethiopian Health Policy has achieved great progress in improving access to comprehensive HIV/AIDS services to the majority of the population. Both quality and coverage of services have improved significantlysince the initiation... more

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Guidelines for Health Staff Caring for Gender-based Violence Survivors: Including Protocol for Clinical Management of Rape [EN]

UN High Commissioner for Refugees, Protection Cluster, Health Cluster (2016) C1

Gender-based violence, including rape is a problem throughout the world, occurring in every society, country and region. Refugees and internally displaced people are particularly at risk of this violation during every phase of an emergency situation. The systematic use of sexual violence as a method... more

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Mapping of stakeholders and initiatives on early warning systems in Myanmar

Malteser International (2015) C1

This study aims to analyze national and international stakeholders and their initiatives in Early Warning Systems in Myanmar, to identify priority gaps that need to be addressed by all stakeholders. It is presented as a first step towards supporting GoUM in information-gathering under the Myanmar Ac... more

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Rwanda: FAMILY PLANNING STRATEGIC PLAN 2012–2016

Ministry of Health, Rwanda (2012) C2

In recent years, Rwanda has been on the fast track to achieve major health improvements for its entire population. With the support of government agencies and various non-governmental partners, the Ministry of Health (MoH) has endeavored to decentralize Rwanda’s health system and bring health serv... more

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Ethiopia - Multi-Sectorial Cholera Elimination Plan 2022 - 2028

Government of Ethiopia (2023) C2

The Ethiopia Multi-Sectorial Cholera Elimination Plan (2022-2028) outlines a national strategy to eliminate cholera in Ethiopia by 2028. The plan follows the Global Roadmap to End Cholera by 2030 and is based on six key pillars: Leadership & Coordination, Water, Sanitation & Hygiene (WASH), Surveill... more

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Injury Prevention and Environmental Health. Disease Control Priorities, Third Edition : Volume 7

Mock, Charles N.; Nugent, Rachel; Kobusingye, Olive; et al. World Bank (2017) CC

The substantial burden of death and disability that results from interpersonal violence, road traffic injuries, unintentional injuries, occupational health risks, air pollution, climate change, and inadequate water and sanitation falls disproportionally on low- and middle-income countries. Injury Pr... more

Inclusion of Persons with Disabilities in Humanitarian Action recommended

Inclusion of Persons with Disabilities in Humanitarian Action
recommended