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Publication Years
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Toolboxes
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1
This guidance document, titled 'Preparedness Enabler's Guide (PEG)', published in May 2023, aims to promote effective and sustainable localization in humanitarian preparedness through insights and practical tools derived from the Global Logistics Cluster's experience.
A toolkit designed to support with developing effective community engagement strategies for different emergencies with specific tools for natural hazards, conflicts, disease outbreaks, epidemics, and complex emergencies.
The purpose of this interim guidance is to provide recommendations for planning and implementing RCCE activities that protect and empower communities during MVD outbreaks. The guidance is designed for national and subnational health responders involved in RCCE for MVD readiness and response. It is a
...
lso relevant to other stakeholders, such as partner organizations, ministries (such as those involved in social protection), and academics, who contribute to RCCE activities. The document is meant to be adapted alongside national multi-risk/ multisectoral plans, leveraging existing expertise, coordination mechanisms and partnerships.
more
The resurgence of mpox in multiple African countries since 2022 has highlighted urgent gaps in preparedness, detection, and response capacities across the continent. While the mpox outbreak was initially classified as a Public Health Emergency of International Concern (PHEIC) and a Public Health Eme
...
rgency of Continental Security (PHECS), the risk of continued transmission in high-risk areas of Africa remains significant, particularly due to persistent zoonotic reservoirs, cross-border spread, and fragile surveillance systems.
more
Sustaining HIV Community-led Responses: Technical guidelines for costing and budgeting
UNAIDS
(2026)
Community-led responses (CLRs) are a vital pillar of the HIV response and central to achieving national and global targets, including the 30-80-60 commitments outlined in the 2021 Political Declaration on HIV and AIDS. These guidelines provide practical, step-by-step methods for costing and budgetin
...
g community-led responses (CLRs), tailored to the unique features of CLRs. They are designed for use by community-led organizations (CLOs), their partners, national governments, policy-makers, donors, and researchers involved in planning, implementing, financing or evaluating CLRs that address HIV.
more
Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
recommended
New
The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
...
s Guidelines outlines a structured approach to decentralization, focusing on:
Strategic Goals: Strengthening laboratory capacity at subnational levels to ensure timely detection and control of epidemic-prone diseases.
Guiding Principles: Equity, country ownership, multisectoral collaboration and evidence-based decision-making.
Implementation Framework: Practical steps for planning, executing, and sustaining decentralized diagnostic networks, with intra- and post-implementation reviews for continuous improvement.
Integration: Alignment with existing surveillance, case management and infection prevention and control (IPC) systems, with a focus on the One Health approach.
While the Guidelines is informed by the Mpox outbreak response, it is adaptable to other priority diseases and aligned with the International Health Regulations (IHR 2005), the Africa CDC Strategic Plan (2022-2027), and the WHO Health Security Framework.
more
Préparatiom et la riposte aux Épidémies er Afrique guide de Décentralisation des capacités de Laboratoire
recommended
New
L’augmentation en fréquence et en ampleur des urgences de santé publique en Afrique met en évidence
l’importance cruciale d’un dépistage précoce, d’une intervention rapide et d’un accès équitable aux
capacités de laboratoire. Les systèmes centralisés se sont souvent révélés
...
insuffisants, notamment
dans les zones reculées ou mal desservies, entraînant des retards dans la confirmation des cas et
réduisant l’efficacité des mesures de contrôle des épidémies.
La décentralisation des capacités de laboratoire constitue une stratégie transformative pour combler
ces lacunes. En rapprochant les examens diagnostiques des points de prestation de soins, les États
Membres de l’Union Africaine peuvent détecter les épidémies plus tôt, réagir plus efficacement et
renforcer la confiance du public dans les systèmes de santé.
Ce document propose un cadre global pour aider les États Membres à concevoir, mettre en œuvre
et pérenniser des réseaux de diagnostic décentralisés. Il met l’accent sur l’équité, l’appropriation
nationale, la collaboration multisectorielle et l’intégration avec les autres fonctions du système de santé.
De plus, il souligne l’importance du maintien des normes de qualité dans les contextes décentralisés,
en recommandant la mise en place de dispositifs de contrôle qualité adaptés, de mécanismes de
supervision ciblés et l’harmonisation avec les cadres nationaux d’assurance qualité.
Africa CDC, l’OMS et leurs partenaires restent déterminés à soutenir les États Membres à travers une
assistance technique, des plateformes de coordination et la mobilisation de ressources. Ensemble,
nous pouvons bâtir un écosystème de diagnostic résilient, réactif et inclusif, protégeant la santé de
toutes les communautés africaines.
more
medRxiv- The preprint server for health sciences
recommended
Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv
Researchers are devising a clinical-trial protocol to test three medicines in Africa's latest outbreak
Nature doi: 10.1038/d41586-018-06132-7
NICE Scientific Advice is providing free fast track advice for researchers who are developing novel diagnostics or therapeutics for COVID-19. The team is working to help researchers from around the world optimise their approach to generating the essential evidence required for health technology ass
...
essments, which inform decision making.
more
COVID-19 vaccine tracker and landscape
recommended
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline.
The COVID-19 vaccine tracker:
Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-
...
clinical development;
Provides analysis and visualization for several COVID-19 vaccine candidate categories;
Tracks the progress of each vaccine from pre-clinical, Phase 1, Phase 2 through to Phase 3 efficacy studies and including Phase 4 registered as interventional studies;
Provides links to published reports on safety, immunogenicity and efficacy data of the vaccine candidates;
Includes information on key attributes of each vaccine candidate and
Allows users to search for COVID-19 vaccines through various criteria such as vaccine platform, schedule of vaccination, route of administration, developer, trial phase and clinical endpoints.
The database is updated regularly - twice a week (Tuesday and Friday, 17:00 CET).
more
تقوم الأدوية التقليدية أو الأدوية النباتية المعتمدة على الأعشاب بدور كأدوية بديلة. عليه، فإنه من المهم ٍ واسعٍم على نطاقَستخدُالأمراض في إفريقيا وتتقييم كلٍّ من س
...
امة
وفعالية هذه الأصول النباتية الأصلية في الطب قبل المصادقة والجمهور.على استخدامها من قبل المجتمع الطبي
more
تطوير لقاح مرض فيروس كورونا ] واستراتيجية المستجد [COVID-19
PLoS ONE 13(11): e0207554. https://doi.org/ 10.1371/journal.pone.020755
WHO’s sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy is intended for easy and frequent implementation. Results from sentinel surveys provide insight into the prevalence and year-over-year trends of dolutegravir resi
...
stance in adults, children and adolescents receiving dolutegravir-based ART.
This sentinel method is implemented complementary to WHO-recommended methods for estimating nationally representative levels of acquired HIV drug resistance.
more
Journal of Infectious Diseases and Therapeutics, 2013, 1, 17-24
