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A comprehensive systematic review for identifying the risk factors for carrying aTrypanosoma cruzi infection in non-endemic countries

European Centre for Disease Prevention and Control ECDC (2024) CC

Mass population movements have accounted for the emergence of Chagas disease (CD) outside endemic regions, including the European Union/European Economic Area (EU/EEA). The parasite responsible for causing CD, Trypanosoma cruzi (T. cruzi), can be transmitted through substances of human origin (SoH... more

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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

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HIV/AIDS prevention, care and treatment in the Region of the Americas: achievements, challenges and perspectives

F. Pérez; G. Ravasi; J. Peter Figueroa; et al. PAHO (Pan American Health Organization; World Health Organization); Iris (Institutional Repository); Rev Panam Salud Publica; Pan American Journal of Public Health (2016) C2

Overview Rev Panam Salud Publica 40(6), 2016

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Nurse-driven, community-supported HIV/AIDS treatment at the primary health care level in rural Lesotho

MSF South Africa and Lesotho Medecins Sans Frontieres (2009) C2

2006-2008 programme report

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Provision and continuation of antiretroviral therapy during acute conflict: the experience of MSF in Central African Republic and Yemen

Ferreyra C., D. O’Brien, B. Alonso Conflict and Health (2018) C2

Unstable settings present challenges for the effective provision of antiretroviral treatment (ART). In this paper, we summarize the experience and results of providing ART and implementing contingency plans during acute instability in the Central African Republic (CAR) and Yemen.

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Challenges of DHS and MIS to capture the entire pattern of malaria parasite risk and intervention effects in countries with different ecological zones: the case of Cameroon

Massoda Tonye, S.G. ; C. Kouambeng, R. Wounang et. al. Malaria Journal (2018) C1

Massoda Tonye et al. Malar J (2018) 17:156 https://doi.org/10.1186/s12936-018-2284-7 Background: In 2011, the demographic and health survey (DHS) in Cameroon was combined with the multiple indicator cluster survey. Malaria parasitological data were collected, but the survey period did not overl... more

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A New Agenda for Mental Health in the Americas: Report of the Pan American Health Organization High-Level Commission on Mental Health and COVID-19

Pan American Health Organisation PAHO (2024) C_WHO

Unmet mental health needs in the Region of the Americas are a leading source of morbidity and mortality, which result in tremendous health, social, and economic consequences. The COVID-19 pandemic has exacerbated the mental health crisis in the Region, necessitating urgent action at the highest leve... more

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Reducing hospital-acquired infections and improving the rational use of antibiotics in a developing country: an effectiveness study

Murni I. K., T. Duke, S. Kinney et al. (2014) C2

Nosocomial infections, or hospital-acquired infec-tions (HAI), are among the most significant causesof morbidity and mortality in healthcare settingsthroughout the world.Prevention of HAIs iscentral to providing high quality and safe health-care, even in settings with limited resources.Transmi... more

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Hand hygiene in health care in the context of Filovirus disease outbreak response. Rapid advice guideline
recommended

World Health Organization (2014)

This document provides a summary of the recommendations for hand hygiene best practices to be performed by health workers providing care and/or support to patients with filovirus infection (Ebola and Marburg viruses).

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Updated WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage

USAID, MCSP; World Health Organization (2017) C_WHO

This summary brief highlights key messages from the updated World Health Organization’s recommendation on tranexamic acid (TXA) for the treatment of postpartum haemorrhage (PPH), including policy and program implications for translating the TXA recommendation into action at the country level. In 2... more

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Tuberculosis and HIV co-infection—focus on the Asia-Pacific region

Q.M. Trinh; H.L. Nguyen; V.N. Nguyen International Journal of Infectious Diseases; Elsevier Ltd (2014) C2

International Journal of Infectious Diseases 32 (2015) 170–178 http://dx.doi.org/10.1016/j.ijid.2014.11.023 1201-9712/ß 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http:... more

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Caring for Newborns and Children in the Community. Facilitator Notes

World Health Organization; UNICEF (2011) C_WHO

Treat diarrhoea, confirmed malaria, and fast breathing

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Essential Package of Health Services (EPHS). Secondary & Tertiary Care: The District, County & National Health Systems (Liberia)
recommended

Ministry of Health & Social Welfare, Liberia (2011) C1

Essential Drug list on page 36!!

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Drug-resistant tuberculosis in Central Mozambique: the role of a rapid genotypic susceptibility testing

Evangelina IN, Inês T, Miguelhete L et al (2016) CC

This study consists of a descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014–2015, being the first report of a genotypic testing used to provide information about second line drug resistance in Mozambique. BMC Infectious Diseases (2016) 16:423 DO... more

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Regional Framework for Action on Implementation of the End TB Strategy in the Western Pacific, 2016–2020

World Health Organization, Western Pacific (2016) C_WHO

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Integration of Water, Sanitation, and Hygiene for the Prevention and Control of Neglected Tropical Diseases: A Rationale for Inter-Sectoral Collaboration

Freeman, M.C.; Ogden, S.; Jacobson, J. et al PLoS Neglected Tropical Diseases (2013) C2

https://doi.org/10.1371/journal.pntd.0002439 South Sudan has a high burden – among the highest in sub-Saharan Africa – of neglected tropical diseases (NTDs). This adversely affects the health and social and economic well-being of people in the country. The prevention, control and eventual elim... more

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Dual HIV/syphilis rapid diagnostic tests can be used as the first test in antenatal care

World Health Organization WHO (2019) C_WHO

Policy Brief. WHO recommends that pregnant women receive testing for HIV, syphilis and hepatitis B (HBSAg) at least once during pregnancy, preferably in the first trimester. Dual HIV/syphilis rapid diagnostic tests (RDTs) can be used as the first test for pregnant women as part of antenatal care (... more

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Quantitative evaluation of essential medicines lists: the South African case study

Velisha Ann Perumal-Pillay & Fatima Suleman BMC Health Services Research (2016) CC

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Treatment of tuberculosis - Annex 5 Reports of the systematic reviews

World Health Organization (2017) C_WHO

Guidelines for treatment of drug-susceptible tuberculosisand patient care 2017 Update

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Putting HIV and HCV to the test - A product guide for point-of-care CD4 tests and laboratory-based and point-of-care HIV and HCV viral load tests

Medecins Sans Frontieres (Access Campaign) (2017) C2

3rd Edition – July 2017 www.msfaccess.org

Hand hygiene in health care in the context of Filovirus disease outbreak response. Rapid advice guideline recommended

Essential Package of Health Services (EPHS). Secondary & Tertiary Care: The District, County & National Health Systems (Liberia) recommended

Hand hygiene in health care in the context of Filovirus disease outbreak response. Rapid advice guideline
recommended

Essential Package of Health Services (EPHS). Secondary & Tertiary Care: The District, County & National Health Systems (Liberia)
recommended