Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and
blindness. But the epidemiological situation has improved dramatically over the last two decades.... Community directed treatment with ivermectin has effectively brought the disease under control in most endemic areas where onchocerciasis is no longer a public health risk.
more
Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the endemic areas in sub-Saharan Africa. HAT transmission l...ast soared in the late 1990s, triggering a renewed, coordinated and very successful control effort. In this paper, we present achievements towards HAT elimination, with a focus on the WHO road map targets for 2020. In particular, reported cases continue to decline, from over 30,000 cases per year at the turn of the century to 663 cases in 2020. Despite the impact of the COVID-19 pandemic, HAT surveillance was largely sustained, and the network of health facilities able to diagnose and treat the disease further expanded. Looking to the future, the World Health Organization (WHO) set bold new targets for HAT in its 2021–2030 road map for NTDs, namely: the elimination of transmission of gambiense HAT, which occurs in western and central Africa, and the elimination as a public health problem of rhodesiense HAT, which is found in eastern and southern Africa. The strong commitment of national health authorities and the international community will be essential if these goals are to be achieved.
more
In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and breastfeeding women be offered treatment, with praz...iquantel, either individually or during treatment campaigns. In 2006, WHO also stated the need for randomized controlled trials to assess the safety and efficacy of such treatment. Some countries have yet to follow the recommendation on treatment and many programme managers and pregnant women in other countries remain reluctant to follow the recommended approach.
more
Foodborne trematodiases are caused by parasitic trematode worms. People become infected by eating raw or undercooked fish, crustaceans and vegetables that contain the larval worms.
It is estimated that, in Latin America alone, between 6 and 8 million people are infected with the parasite, and 99% of these are not receiving treatment, either because they are unaware of their infection or because they do not know that treatment exists. The potential spread of the disease is also... a cause for considerable concern: 65 million people live in areas of exposure and are at risk of contracting Chagas disease, and 28,000 new cases occur every year.
more
A recent study informed that ivermectin was successfully used in vitro for the treatment of SARS-CoV-2 in experimentally infected cells and two preprint publications on observational clinical studies reported the apparent utility of ivermectin to treat patients with COVID-19 needing mechanical venti...lation. However, neither of these studies were peer-reviewed nor formally published and one of them was later retracted.
more
Se calcula que en 2015 había en el mundo 17,8 millones de mujeres de 18 años o mayores infectadas por el VIH, cifra que equivale al 51% de los adultos que viven con VIH. Las adolescentes y las jóvenes se ven especialmente afectadas; en 2015 constituían el 60% de los individuos entre 15 a 24 año...s de edad que vivían con el VIH, representando también el 58% de las infecciones por el VIH de adquisición reciente en los jóvenes de ese grupo de edad. En muchos países las mujeres que viven con el VIH carecen de acceso equitativo a servicios de salud de buena calidad, y enfrentan muchas formas de estigma y discriminación que se entrecruzan. Más aun, estas mujeres son desproporcionadamente vulnerables a la violencia, en particular las violaciones de sus derechos sexuales y reproductivos.
more
Datos y cifras
Se calcula que en el mundo hay entre 6 y 7 millones de personas infectadas por el Trypanosoma cruzi, el parásito causante de la enfermedad de Chagas, la mayoría de ellas en América Latina.
La infección por Trypanosoma cruzi se puede curar si el tratamiento se administra al poco ...tiempo de producirse la infección.
Hasta un 30% de los enfermos crónicos presentan alteraciones cardíacas y hasta un 10% padecen alteraciones digestivas, neurológicas o combinadas que pueden requerir un tratamiento específico.
El control de vectores y otras estrategias destinadas a reducir la transmisión que estos producen son los métodos más útiles para prevenir la enfermedad de Chagas en América Latina.
Los análisis de sangre son fundamentales para prevenir la infección por transfusiones o trasplantes de órganos en todo el mundo.
La detección y el tratamiento de niñas infectadas y mujeres infectadas en edad fértil es clave, además del cribado de los recién nacidos y otros hijos de madres infectadas que no hayan recibido antes tratamiento antiparasitario.
La enfermedad de Chagas, también llamada tripanosomiasis americana, es una enfermedad potencialmente mortal causada por el parásito protozoo Trypanosoma cruzi (T. cruzi).
more
La dracunculosis rara vez es mortal, pero las personas infectadas quedan incapacitadas durante semanas o meses. Afecta a personas de comunidades rurales, desfavorecidas y aisladas que para beber dependen principalmente de fuentes superficiales abiertas en que el agua se estanca, como charcas o estan...ques.
more
Bula da vacina foi atualizada com nova recomendação para vacina da dengue da Sanofi Aventis para pessoas nunca infectadas pela dengue.
El virus se transmite por el contacto directo con las gotas de la respiración que una persona infectada puede expulsar cuando tose o estornuda, o al tocar superficies contaminadas por el virus. El COVID-19 puede sobrevivir en una superficie varias horas, pero puede eliminarse con desinfectantes sen...cillos.
more
Los residuos generados por las actividades sanitarias, desde agujas infectadas hasta isótopos radiactivos, pueden ser una fuente de infecciones o lesiones y su gestión inadecuada puede tener graves consecuencias para la salud pública y efectos nocivos para el medio ambiente.
...staca los aspectos clave de la gestión segura de los residuos médicos para orientar a los responsables políticos, a los profesionales y a los gestores de las instalaciones para mejorar estos servicios en los centros sanitarios.
more
Each year 1–2 million people are diagnosed with a tropical disease called leishmaniasis, which is caused by single-celled parasites. People are infected when they are bitten by sandflies carrying the parasite, and often develop skin lesions around the bite site. Though mild cases may recover on th...eir own or with treatment, sometimes the parasites multiply and spread elsewhere causing further skin lesions and facial disfigurement. Furthermore, the parasites can also infect internal organs such as the spleen and the liver, which without treatment can be fatal.
more
Rev. Panam Salud Publica. 2017;41:e153. doi: 10.26633/RPSP.2017.153
Worldwide, over 6 million people are infected with Trypanosoma cruzi, the pathogen that causes Chagas disease (CD). In the Americas, CD creates the greatest burden in disability-adjusted life years of any parasitic infection. In Co...lombia, 437 000 people are infected with T. cruzi, of whom 131 000 suffer from cardiomyopathy. Colombia’s annual costs for treating patients with advanced CD reach US$ 175 016 000. Although timely etiological treatment can significantly delay or prevent development of cardiomyopathy—and costs just US$ 30 per patient—fewer than 1% of people with CD in Colombia and elsewhere receive it.
more
The consortium is an international public-private partnership that aims to reduce the global disease burden of schistosomiasis by addressing the medical needs of infected children between the ages of 3 months and 6 years. By doing so, we hope to contribute to the ongoing efforts to eliminate schisto...somiasis and improve child health.
more
Leishmaniasis is an infectious disease caused by protozoan parasites of the genus, Leishmania. Protozoa are microscopic, single-celled organisms. The parasites that cause the disease are transmitted to people through the bites of certain species of infected sand flies.
Rabies remains an under-reported neglected zoonosis with a case-fatality rate of almost 100% in humans and animals. Dog-mediated human rabies causes tens of thousands of human deaths annually despite being 100% preventable. More than 95% of human cases are caused by the bite of a rabies-infected dog.... Dog-mediated human rabies disproportionately affects rural communities, particularly children, and economically disadvantaged areas of Africa and Asia, where awareness of the disease and access to appropriate post-exposure prophylaxis (PEP) can be limited or nonexistent.
more
Cases of monkeypox (MPX) acquired in the EU have recently been reported in nine EU Member States (Austria, Belgium, France, Germany, Italy, Portugal, Spain, Sweden, and the Netherlands).
Monkeypox (MPX) does not spread easily between people. Human-to-human transmission occurs through close contact ...with infectious material from skin lesions of an infected person, through respiratory droplets in prolonged face-to-face contact, and through fomites. The predominance, in the current outbreak, of diagnosed human MPX cases among men having sex with men (MSM), and the nature of the presenting lesions in some cases, suggest transmission occurred during sexual intercourse
more
The five hepatitis viruses have different epidemiological profiles, and their impact, duration, and transmission route also vary. The most common transmission routes contributing to the spread of hepatitis are exposure to infected blood via blood transfusion or unsafe injection practices, consumptio...n of contaminated food and drinking water, and transmission from mother to child during pregnancy and delivery. Also, unsafe injection practices, including the use of unsterile needles and syringes, serve as a major pathway for the spread of hepatitis B and C, and reducing transmission of both diseases requires addressing these practices.
more
Leptospirosis is a zoonotic disease with epidemic potential, especially after a heavy rainfall,
caused by a bacterium called Leptospira. Leptospira interrogans is pathogenic to humans and
animals, with more than 200 serologic variants or serovars. Humans usually acquire
leptospirosis through dire...ct contact with the urine of infected animals or a urine-contaminated
environment. Human-to-human transmission occurs only very rarely. Leptospirosis may present
with a wide variety of clinical manifestations, from a mild illness that may progress to a serious
and sometimes fatal disease. Its symptoms may mimic many diseases, such as influenza,
dengue and other viral haemorrhagic diseases; making the correct diagnosis (clinical and
laboratory) at the onset of symptoms is important to prevent severe cases and save lives,
primarily in outbreak situations.
more