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Multidrug-resistant tuberculosis in migrants, multi-country cluster - third update, 13 April 2017

European Centre for Disease Prevention and Control (2017) C1

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Antibiotic resistance: How does antibiotic resistance spread?

European Centre for Disease Prevention and Control (2014) C2

Antibiotic resistance is a natural occurrence caused by mutations in bacteria’s genes. However, inappropriate use of antibiotics accelerates the emergence and spread of antibiotic-resistant bacteria. When exposed to antibiotics, susceptible bacteria are killed; while excessive antibiotic use or th... more

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Antimicrobial Resistance in the EU/EEA

European Centre for Disease Prevention and Control ECDC; WHO Europe; OECD; et al. (2022) CC

A One Health Response. A Briefing Note

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Towards One Health preparedness: expert consultation 11–12 December 2017

European Centre for Disease Prevention and Control ECDC (2018) CC

Climate change, increasing population densities, and intensified globalisation in trade, travel and migration are among the most important factors shaping the 21st century. Each impacts upon population health and the risk of infectious disease, particularly those originating at the human-animal-envi... more

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Factsheet for health professionals about chikungunya

European Centre for Disease Prevention and Control ECDC (2025) C_CDC

Chikungunya is a viral disease transmitted by Aedes mosquitoes to humans. The word ‘chikungunya’ means 'that which bends up', an allusion to the posture of the suffering patients. The most common clinical form associates fever, arthralgia and rash. Recovery is the usual outcome but chronic arthr... more

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Методы обнаружения и описания вариантов SARS-CoV-2 – первое обновление. 20 декабря 2021 г.

European Centre for Disease Prevention and Control ECDC; WHO Europe (2021) C1

20 Dec. 2021

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Evaluation of ECDC Ebola deployment in Guinea

Kokki, M.; Safrani, N. European Centre for Disease Prevention and Control (2017) C1

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Diretrizes Africanas de Tratamento com Antibióticos para Infeções e Síndromes Bacterianas Comuns

Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy (2021) CC

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Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ...is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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Structure de surveillance basée sur les événements

Africa Center for Disease Control and Prevention (2023) CC

Le cadre de surveillance basé sur les événements est destiné à être utilisé par les autorités et les agences responsables de la surveillance et de l'intervention. Ce cadre sert de cadre pour guider les parties prenantes intéressées par la mise en œuvre de la surveillance basée sur le... more

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Africa CDC Event-based Surveillance Resources - Arabic Version

Africa Center for Disease Control and Prevention (2023) CC

ي الغرض من إطار عمل إجراءات المراقبة القائمة عىل األحداث هو أن به ن تستعي السلطات والوكاالت المسؤولة عن المراقبة ُ واالستجابة. كما تيب إرشال تعىل سبيل المثال؛ هذ...ه الوثيقة ألصحاب المصلحة ي ُ ُعد بمثابة ك ا عاما ي إطار استخدام ي الذين يرغبون ف ن نهج "صحة واحدة" متعدد القطاعات لتنفيذ المراقبة القائمة عىل األحداث . و للقيام بذلك، تشتمل الوثيقة عىل فصول وملحق ن مرتبطة ويمكن للمستخدمي تغييها وتحديثها بناء عىل احتياجاتهم الخاصة. ُعد هذه الت ي وت نسخة منقحة من النسخة األصلية "إطار عمل المراقبة القائمة عىل األحداث" عام ي ن صدرت ف 2018 .و ال ينسخ إطار العمل هذا أو يحل محل أي مواد أخرى متاحة حاليا في ما يتعلق بمج ال المراقبة القائمة عىل األحداث أن ن ؛ وبدال من ذلك، ينبعي يستند إطار العمل إل الوثائق الموجودة سابقا ذات الصلة أو مرتبطة وأن يكون تيب ُ ك ا إرشاديا عملي ا لتنفيذ المراقبة القائمة عىل األحداث أفريقيا. ي ن ف ويتوافق إطار العمل ك لمنظمة الصحة العالمية المشي ي هذا مع الطبعة الثالثة من التقييم الخارج فيما يتعلق ر بالمؤشات التالية: تعزيز ي عىل كشف األحداث ذات األهمية للصحة العامة واألمن الصح أنظمة المراقبة و اإلنذار المبكر القادر ة ر المؤش ) حسنة والتعاون عي القطاعات وبين 1.D2)؛ مستويات استجابة الصحة العمومية الوطنية والمتوسطة ُ وقنوات االتصال الم العامة واألمن الصح والمحلية فيما يتعلق بمراقبة األحداث ذات األهمية للصحة ي ر )المؤش ن 2.D2)؛ القدرة عىل وتحسي تحليل ن البيانات عىل المستوى المتوسط والوطت ي ر )المؤش رش 3.D2 .)باإلضافة إل وع الدول تنفيذ و ي ن ف عرض مهام ووظائف المراقبة القائمة عىل األحداث إذ ، اللوائح الصحية ي درجات التقييم المشي ك وإحراز تقدم نحو تلبية المتطلبات المبينة ف ن ي ستضمن زيادة ف ن الدولية . تحسين أيضا، تنفيذ المراقبة المتكاملة لألمراض واالستجابة لها، وذلك بالنسبة ي ن تعد هذه الوثيقة مكملة ويمكن أن تساعد ف ل لدول ا ي االتحاد األفريق ي ن اعتمدت االسي األعضاء ف اتيجية المتكاملة لمراقبة األمراض واالستجابة لها، لت عىل وجه الخصوص ي بالنسبة للطبعة الثالثة ) 2019 تتضمن أجزاء حول ( الت المراقبة القائمة عىل األحداث ي . more

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Estrutura de vigilância baseada em evento

Africa Center for Disease Control and Prevention (2023) CC

A Estrutura de Vigilância Baseada em Eventos deve ser usada por autoridades e agências responsáveis pela vigilância e resposta. Essa estrutura serve como um esboço para orientar as partes interessadas em implementar a vigilância baseada em eventos (EBS) usando uma abordagem multissetorial ... more

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Guidance for the continuation of essential health services during COVID-19 pandemic

Africa CDC Centers for Disease Control and Prevention (2020) CC

This document provides guidance for African Union Member States on actions to be taken to ensure they continue to meet all the health needs of their citizens in accordance with achieving the objectives of the Africa Health Strategy 2016 – 2030.

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Guidance on easing lockdown

Africa CDC Centers for Disease Control and Prevention (2020) CC

In response to the first cases of coronavirus disease 2019 (COVID-19) reported on the continent, many African Union Member States implemented large-scale public health and social measures (PHSM) rapidly. These measures were aimed at reducing transmission and the number of new cases being reported, p... more

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Continental Framework on Strengthening Mortality Surveillance Systems in Africa

Africa Center for Disease Control and Prevention (2023) CC

The importance of robust mortality surveillance systems cannot be overstated in an era marked by increasing global health challenges where health threats loom large and population dynamics continue to evolve. Accurate and timely mortality data is essential for identifying trends and detecting emergi... more

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Cadre continental sur le renforcement des systèmes de surveillance de la mortalité en Afrique

Africa Center for Disease Control and Prevention (2023) CC

L'importance de systèmes de surveillance de la mortalité robustes ne peut être surestimée à une époque marquée par des défis sanitaires mondiaux croissants, où les menaces sanitaires pèsent lourd et la dynamique des populations continue d'évoluer. Des données précises et opportunes sur ...la mortalité sont essentielles pour identifier les tendances et détecter les menaces émergentes pour la santé, évaluer l'impact des interventions et orienter les décisions politiques fondées sur des données probantes. Ce cadre décrit une approche holistique pour renforcer les systèmes de surveillance de routine de la mortalité, en tenant compte des facteurs contextuels uniques et des défis auxquels sont confrontés les pays africains. Il souligne l'importance d'établir des mécanismes de collecte de données efficaces, d'améliorer la qualité et l'exhaustivité des données et de promouvoir le partage des données et la collaboration entre les parties prenantes. De plus, le cadre reconnaît le rôle central de la technologie dans l'intégration des données provenant de sources de données fragmentées sur la mortalité. Il met en évidence le potentiel des méthodes innovantes de capture de données, des analyses avancées et des systèmes de notification en temps réel pour améliorer la précision, l'efficacité et l'actualité des données sur la mortalité. Le cadre continental de surveillance de la mortalité s'aligne sur la mission et l'objectif stratégique d'Africa CDC en servant d'élément fondamental dans le renforcement des systèmes de santé publique, l'amélioration des capacités et des capacités de surveillance des maladies, l'élaboration de politiques et d'interventions fondées sur des données probantes et la promotion de la collaboration et de la coordination entre les pays africains pour relever les défis sanitaires et améliorer les résultats sanitaires sur le continent. La mise en œuvre réussie de ce cadre nécessite un engagement collectif et des efforts concertés de la part des gouvernements, des établissements de santé et de la communauté internationale. Nous espérons que ce document servira de catalyseur pour un changement transformateur, permettant aux pays de mettre en place des systèmes de surveillance de la mortalité résilients qui protègent la santé publique, sauvent des vies et contribuent à la prise de décision fondée sur des données probantes. more

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Troca de Informacao Sobre Saude Diretrizes e padrões

Africa Center for Disease Control and Prevention (2023) CC

A aplicação da tecnologia digital de saúde está crescendo rapidamente na África, com o objetivo de melhorar a prestação de serviços de saúde e alcançar de forma mais eficaz comunidades remotas e carentes. A falta de diretrizes e padrões habilitadores em todo o continente, por outro ... more

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What are antibiotic-resistant bacteria?

CDC Centers for Disease Control and Prevention (2019) C_CDC

Antibiotic resistance occurs when bacteria no longer respond to the drugs designed to kill them. Anytime antibiotics are used, they can cause antibiotic resistance.