Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu...s diagnoses by three pediatricians who were guided by study definitions that were based on medical history, physical examination findings, laboratory and radiological tests, and response to bronchodilators. Children with asthma or bronchiolitis were categorized as “asthma syndrome”. Using this approach, 253 (41.2%) had asthma syndrome. History of and present breathing difficulties and present cough and wheezing was the best performing combination of four questionnaire items [sensitivity 80.8% (95% CI 77.6–84.0); specificity 84.7% (95% CI 81.8–87.6)]. The screening tool for asthma syndrome in ‘under-fives’ may provide a simple, cheap and quick method of identifying children with possible asthma. The validity and reliability of this tool in primary care settings should be tested.
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An Examination of 13 Projects in PEPFAR-Supported Countries
The figures and findings reflected in the 2019 Humanitarian Needs Overview (HNO) represent the independent analysis
of the United Nations (UN) and its humanitarian partners based on information available to them. While the HNO aims
to provide consolidated humanitarian analysis and data to help inf...orm joint strategic humanitarian planning, many of
the figures provided throughout the document are estimates based on sometimes incomplete and partial data sets using
the methodologies for collection that were available at the time. The Government of Syria has expressed its reservations
over the data sources and methodology of assessments used to inform the HNO, as well as on a number of HNO findings.
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Coronavirus disease 2019 is also known as COVID-19. It is a viral illness that infects the lungs. It is caused by a virus called SARS-associated coronavirus (SARS-CoV-2). This illness was first seen in late 2019 in China and has spread across the world.
The signs of COVID-19 are like the flu, and y...ou may have a cough, fever, and it may be hard to breathe. It spreads easily through droplets with the virus when you sneeze or cough. The germs also survive on surfaces like tables, door handles, and telephones. That means you can become sick if you touch a surface with the virus and then touch your face.
Some people have a mild case of COVID-19 and are able to stay at home until they feel better. Others may need to be in the hospital if they are very sick. People with COVID-19 most often have to isolate themselves for about 2 weeks.
Last Reviewed Date: 2020-03-16
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Learning sheet no. 4
Accessed March, 2025
How to successfully apply for, administer, and manage the Zithromax® donation for trachoma elimination
Biosafety involves the implementation of containment principles, technologies and practices to prevent unintentional exposure to biological agents. Biosecurity involves the protection, control and accountability of biological materials and information related to these materials and dualuse research,... to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
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Now entering its sixth year, the conflict in Syria continues to take a drastic toll on the lives of the Syrian people and to drive an unprecedented humanitarian and protection crisis: some 13.5 million people are now in need of humanitarian assistance and protection, including 6 million children. Ha...lf of the country’s pre-crisis population has been forced from their homes, with around one third of the remaining population now displaced within Syria and over 4.8 seeking refuge in neighbouring countries and beyond.
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This briefing paper provides an overview of pre-exposure prophylaxis (PrEP) for people planning, commissioning or providing HIV prevention activities in the UK. It does this by reviewing thirty key questions about PrEP and how it might be implemented in the UK.