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Publication Years
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Toolboxes
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This document assembles these best practices and provides a resource for the proper management of equipment in the laboratory to ensure accurate, reliable and timely testing, and maintain a high level of laboratory performance. Improved equipment management also lowers repair costs, lengthens instru
...
ment life, reduces interruption of services due to breakdowns and failures, and enables laboratory accreditation and the achievement of high-quality and accessible laboratory services at all levels of healthcare service delivery.
more
Training material
Key resources include the Manual for Disaster Response Teams, which helps experts plan public communication, exchange information, and manage media, ensuring crucial data reaches humanitarian actors
Lessons learned around RCCE in outbreak responses in East and Southern Africa recognise the need to learn from and strengthen national and cross-border collaboration in the face of frequent public health emergencies. In October 2023, One Health partners conducted a Simulation Exercise in the Mandera
...
region between Ethiopia, Kenya, and Somalia to test cross-border readiness. One of the key recommendations from this workshop was that current and future agreements, plans, and SOPs on One Health Emergency Preparedness and Response (EPR) in all three countries should include RCCE for cross-border situations.
more
This guidance document, titled 'Preparedness Enabler's Guide (PEG)', published in May 2023, aims to promote effective and sustainable localization in humanitarian preparedness through insights and practical tools derived from the Global Logistics Cluster's experience.
The manual elaborates on a wide rang of logistics management issues such as carrying assessements, procurement, storing, transporting and distribution of emergency supplies
Sustaining HIV Community-led Responses: Technical guidelines for costing and budgeting
UNAIDS
(2026)
Community-led responses (CLRs) are a vital pillar of the HIV response and central to achieving national and global targets, including the 30-80-60 commitments outlined in the 2021 Political Declaration on HIV and AIDS. These guidelines provide practical, step-by-step methods for costing and budgetin
...
g community-led responses (CLRs), tailored to the unique features of CLRs. They are designed for use by community-led organizations (CLOs), their partners, national governments, policy-makers, donors, and researchers involved in planning, implementing, financing or evaluating CLRs that address HIV.
more
Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
recommended
New
The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
...
s Guidelines outlines a structured approach to decentralization, focusing on:
Strategic Goals: Strengthening laboratory capacity at subnational levels to ensure timely detection and control of epidemic-prone diseases.
Guiding Principles: Equity, country ownership, multisectoral collaboration and evidence-based decision-making.
Implementation Framework: Practical steps for planning, executing, and sustaining decentralized diagnostic networks, with intra- and post-implementation reviews for continuous improvement.
Integration: Alignment with existing surveillance, case management and infection prevention and control (IPC) systems, with a focus on the One Health approach.
While the Guidelines is informed by the Mpox outbreak response, it is adaptable to other priority diseases and aligned with the International Health Regulations (IHR 2005), the Africa CDC Strategic Plan (2022-2027), and the WHO Health Security Framework.
more
Préparatiom et la riposte aux Épidémies er Afrique guide de Décentralisation des capacités de Laboratoire
recommended
New
L’augmentation en fréquence et en ampleur des urgences de santé publique en Afrique met en évidence
l’importance cruciale d’un dépistage précoce, d’une intervention rapide et d’un accès équitable aux
capacités de laboratoire. Les systèmes centralisés se sont souvent révélés
...
insuffisants, notamment
dans les zones reculées ou mal desservies, entraînant des retards dans la confirmation des cas et
réduisant l’efficacité des mesures de contrôle des épidémies.
La décentralisation des capacités de laboratoire constitue une stratégie transformative pour combler
ces lacunes. En rapprochant les examens diagnostiques des points de prestation de soins, les États
Membres de l’Union Africaine peuvent détecter les épidémies plus tôt, réagir plus efficacement et
renforcer la confiance du public dans les systèmes de santé.
Ce document propose un cadre global pour aider les États Membres à concevoir, mettre en œuvre
et pérenniser des réseaux de diagnostic décentralisés. Il met l’accent sur l’équité, l’appropriation
nationale, la collaboration multisectorielle et l’intégration avec les autres fonctions du système de santé.
De plus, il souligne l’importance du maintien des normes de qualité dans les contextes décentralisés,
en recommandant la mise en place de dispositifs de contrôle qualité adaptés, de mécanismes de
supervision ciblés et l’harmonisation avec les cadres nationaux d’assurance qualité.
Africa CDC, l’OMS et leurs partenaires restent déterminés à soutenir les États Membres à travers une
assistance technique, des plateformes de coordination et la mobilisation de ressources. Ensemble,
nous pouvons bâtir un écosystème de diagnostic résilient, réactif et inclusif, protégeant la santé de
toutes les communautés africaines.
more
Previous Ebola virus disease (EVD) outbreaks offer
lessons for public health experts responding to the 11th
outbreak. This review highlights that responders need
to build more trust with the communities they serve. It
suggests that language is fundamental to that.
This review article provides a comprehensive overview of Ebola Virus Disease (EVD), covering its epidemiology, clinical presentation, diagnosis, treatment, and prevention. It explains that Ebola is a severe zoonotic infection caused by the Ebola virus, most likely originating from fruit bats and tra
...
nsmitted to humans through contact with infected animals or body fluids. The article summarizes the history of Ebola outbreaks in Africa, including the major West African epidemic of 2013–2016 and subsequent outbreaks in the Democratic Republic of Congo. It describes the disease’s clinical course, ranging from nonspecific flu-like symptoms to severe dehydration, multiorgan failure, shock, and death. The authors discuss diagnostic methods, supportive and intensive care management, emerging antiviral therapies and monoclonal antibodies, as well as the development and use of Ebola vaccines. The review also highlights the importance of infection control, contact tracing, community engagement, safe burial practices, and healthcare worker protection in controlling outbreaks. Finally, it addresses long-term complications in survivors and the persistence of Ebola virus in certain body compartments, particularly semen, which may contribute to delayed transmission.
more
This two-site randomised trial compared the effectiveness of a voluntary sector-led, community-based diabetes prevention programme to a waiting-list control group at 6 months, and included an observational follow-up of the intervention arm to 12 months.
he Framework sets the requirements for facilities handling High Consequence Agents and Toxins (HCATs) and guides the implementation of laboratory biosafety and biosecurity practices associated with the design, commissioning, routine operation safe and secure biocontainment laboratories.
The pharmacological treatment of heart failure has evolved over the last three decades since the demonstration of the effect of angiotensinconverting enzyme inhibitors on major cardiovascular events in patients with heart failure with reduced ejection fraction. Composite analysis of heart failure wi
...
th reduced ejection fraction trials and the recent identification of newer drug treatments show early benefits on the major cardiovascular outcomes, ushering in a change of the treatment strategy; from a ‘sequential’ initiation of the treatments to a ‘simultaneous’ initiation to harness the early benefits. The adoption and implementation of these changes at the bedside have been dismal in many healthcare settings. Papua New Guinea, like many other lower-to-middle-income countries, is facing many barriers that impact on the care of heart failure patients. It needs to adopt and implement these changes to provide evidence-based treatment for its people with heart failure with reduced ejection fraction.
more
Standards & Guidelines for Clinics
Improving Quality & Safety of Health Services
