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Interim guidance on strengthening community detection and response during the mpox outbreak

World Health Organization WHO; Inernational Red Cross Federation IFRC (2025) C_WHO
Mpox, previously known as monkeypox, is a viral illness caused by the monkeypox virus (MPXV).1 It causes a painful rash, enlarged lymph nodes, fever, headache, muscle ache, back pain and low energy or feeling sick. In most cases, the symptoms of mpox go away within a few weeks with supportive care ... more
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Strengthening Kangaroo Mother Care at a tertiary level hospital in Zambia: A prospective descriptive study

Muttau, N.; Mwendafilumba, M; Lewis, B. et al. (2022) CC
PLoS ONE 17(9): e0272444. https://doi.org/ 10.1371/journal.pone.0272444. Based on the RE-AIM metrics, our results show that KMC is a feasible intervention that can improve neonatal outcomes among preterm infants in Zambia. The study findings show a promising, practical approach to scaling up KMC in ... more
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Leveraging health infrastructure to optimize HPV vaccination for adolescents in Zambia: Protocol for an implementation study

Miti, S.; Shato, T.; Asante, C. et al. (2023) CC
PLoS ONE 18(5): e0285031. https://doi.org/10.1371/journal.pone.0285031 The study aims to integrate HPV vaccination into routine care in adolescent HIV clinics. To achieve success, we will co-design a package of implementation strategies using a previously successful implementation research approach ... more
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Strengthening Rwanda’s health workforce: Strategies to improve retention in the health sector

World Health Organization WHO (2025) C_WHO
Rwanda’s national health sector is focused on the equitable delivery of high-quality health services. The Government of Rwanda (GoR) recognizes that developing human resources in the health sector is a critical factor to the well-being of the population. Development of the health workforce has bee ... more
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Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?

Sebti, M.; et al. (2024) CC
Pharmaceuticals 2024, 17(6), 691; https://doi.org/10.3390/ph17060691
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Buruli ulcer in Africa: Geographical distribution, ecology, risk factors, diagnosis, and indigenous plant treatment options - A comprehensive review

Osei-Owusu J.; Fordjour Aidoo O.; Eshu F. et al. Heliyon (2023) C2
Buruli ulcer (BU), a neglected tropical disease (NTD), is an infection of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. The disease has been documented in many South American, Asian, and Western Pacific countries and is widespread throughout much of Africa, especially in West ... more
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Fourth annual meeting of the network of Buruli ulcer PCR laboratories in the WHO African Region: Mundi complex, Yaoundé, 24-26 October 2022

World Health Organization WHO (2024) C_WHO
n October 2019, WHO convened the first meeting of the Buruli ulcer laboratory network (BU-LABNET) in Yaoundé, Cameroon, bringing together 11 laboratories from nine countries at the Pasteur Centre of Cameroon (CPC), the network’s Coordinating Centre. The network was formally established at th ... more
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A combined effort of 11 laboratories in the WHO African region to improve quality of Buruli ulcer PCR diagnosis: The “BU-LABNET”

Marion E, Hycenth N, Vedithi SC, et al. (2024) CC
PLoS Negl Trop Dis 16(11): e0010908. https://doi.org/10.1371/journal.pntd.0010908
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Report of the fifth annual meeting of the network of Buruli ulcer PCR laboratories in the WHO African Region, Accra, Ghana, 23-25 October 2023

World Health Organization WHO (2024) C_WHO
The aim of the meeting was to broaden the network’s initiatives. Preliminary work involved integrating laboratory testing for skin NTDs other than Buruli ulcer, such as cutaneous leishmaniasis, mycetoma, leprosy and yaws, while extending the network’s reach to encompass additional laboratories.
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Human African Trypanosomiasis (Sleeping Sickness). The Road to Elimination Revisited—Achievements and Remaining Challenges

Burri, E. MDPI (2020) CC
Printed Edition pdf
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PICO questions, EtD tables, GDG recommendations

World Health Organization WHO (2024) C_WHO
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti ... more
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Criteria and procedures for the verification of elimination of transmission of "T. b. gambiense" to the human population in a given country

World Health Organization WHO (2023) C_WHO
Having established the goal of eliminating transmission of gambiense human African trypanosomiasis (g-HAT) to humans, the HAT-e-TAG considered which elements should be developed to assess this goal.
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Strategic review of traps and targets for tsetse and African trypanosomiasis control

Kuzoe, F.A.; and S. Schofield UNDPWorld Bank (2005) C_WHO
Tsetse traps and targets (insecticide-impregnated screens) function by attracting the flies to a device that collects and/or kills them. Traps can be used for entomological surveillance, and also for control. Targets are simpler than traps, but are not used for surveillance. They are impregnated wit ... more
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti ... more
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An atlas of tsetse and animal African trypanosomiasis in Zimbabwe

Shereni, W.; L. Neves, R. Argilés, et al. (2021) CC
Parasites Vectors 14, 50 (2021). https://doi.org/10.1186/s13071-020-04555-8
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Zithromax Management Guide

International Trachoma Initiative (2019) CC
How to successfully apply for, administer, and manage the Zithromax® donation for trachoma elimination
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School Eye Health Guidelines

The International Agency for the Prevention of Blindness (2024) CC
The IAPB School Eye Health Workgroup has released these guidelines to help deliver standardised comprehensive eye health services to more than 700 million children attending schools around the world. These guidelines direct the planning and implementation of school eye health initiatives for policym ... more
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Diagnostic target product profiles for trachoma surveillance
recommended

World Health Organization WHO (2024) C_WHO
Trachoma is the leading infectious cause of blindness worldwide. In April 2023, it was a public health problem in approximately 40 countries, with an estimated 116 million people at risk and 1.5 million people affected by the late blinding stage of the disease (1). About 84% of those at risk of tr ... more
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Eliminating Trachoma: Accelerating Towards 2020

World Health Organization WHO (2020) C_WHO
Trachoma is the world’s leading infectious cause of blindness. It is one of 18 neglected tropical diseases (NTDs) that affect over one billion of the world’s poorest people.