Onchocerciasis – or “river blindness” – is a parasitic disease caused by the filarial worm
Onchocerca volvulus. It is transmitted through the bites of infected blackflies (Simulium spp.) that
breed in fast-flowing rivers and streams, mostly in remote villages located near fertile land wher...e
people rely on agriculture.
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Volume 2016 | Article ID 5310718 | https://doi.org/10.1155/2016/5310718. Buruli ulcer (BU) is a necrotizing cutaneous infection caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbid effects and misuse of drugs. We review developments in laboratory diagnosis of BU, discuss li...mitations of available diagnostic methods, and give a perspective on the potential of using aptamers as point-of-care.
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DOI: 10.5772/intechopen.102891Little progress has been made since the 1960s and 19. 70s to widen the therapeutic arsenal against Trypanosoma cruzi, the causative pathogen of Chagas disease, which remains a frustrating and perplexing infectious disease. This chapter focuses on the strategic and opera...tional challenges in the clinical drug development of a novel antitrypanosomal agent for Chagas disease. The various elements that contribute to a robust assessment of treatment effect including dose selection, choice of patient population, trial methodology, endpoint measures, and regulatory perspectives are discussed. The learnings herein should serve as resource to help researchers and other stakeholders optimize their clinical development plans and speed delivery of new medicines to patients with Chagas disease.
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Chagas disease is caused by Trypanosoma cruzi. Infection is transmitted to humans when bitten by Triatominae (reduviid, kissing, or assassin) bugs in South and Central America, Mexico, and very rarely in the US. Less commonly, T. cruzi is transmitted via ingestion of sugar cane juice or food contami...nated with infected Triatominae bugs or their feces, transplacentally from an infected mother to her fetus, or via blood transfusion or an organ transplant from an infected donor.
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Education and information about Chagas Disease, Triatomine bugs, Kissing Bugs, fact sheets, information for special groups, prevention and control, epidemiology, diagnosis and treatment for Health Professionals.
Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi. About 6–7 million people worldwide are estimated to be infected with T. cruzi. The disease is found mainly in endemic areas of 21 continental Lati...n American countries, where it has been mostly transmitted to humans and other mammals by contact with faeces or urine of triatomine bugs (vector-borne), known as kissing bugs, among many other popular names, depending on the geographical area.
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Education and information about Chagas Disease epidemiology and risk factors.
Trachoma disease
Trachoma is a sequela following infection by the bacterium Chlamydia trachomatis (C. trachomatis). The disease is preventable, but still the cause of blindness in 1.9 million people world wide.
This video "Buruli Ulcer Disease: Cleaning and Dressing the Ulcer" is part of a multimedia-based module by Richard Phillips, Stephen Sarfo, Emmanuel Adu, Veronica Owusu-Afriyie, and Cary Engleberg (University of Michigan). This video addresses the question: How should Buruli ulcers be cleansed and d...ressed?
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Chagas disease is found mainly in endemic areas of 21 continental Latin American countries. The most common way people are infected with Chagas is through the blood-sucking triatomine bugs, also known as ‘kissing bugs’ (or vinchuca, barbeiro, pito, chinche, chipo in different Latin American coun...tries). The bugs typically live in wall or roof cracks of poorly constructed homes made of materials such as mud, straw and palm thatch. They come out at night to feed on people’s blood while they’re sleeping, then defecate close to the bite. Their faeces contain the parasite, which can then enter the person’s body when they inadvertently smear the bug’s waste into the bite or another skin break, the eyes or the mouth.
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Chagas disease, or American trypanosomiasis, is a condition that causes gradual organ damage. Without treatment, it can be fatal.
This article explains where the T. cruzi parasite is most common and how it can spread. It also outlines the symptoms of Chagas disease and the treatment options avail...able.
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Dickson and Daniel discuss lymphatic filariasis caused by the helminths Wuchereria bancrofti and Brugia malayai.
You Tube video on Chagas Disease
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their use as predictors of time to healing.
Buruli ulcer (BU), the second most common mycobacterial disease in West Africa, is a necrotizing skin disease that can lead to high morbidity in affected patients. The disease is caused by Mycobacterium ulcerans (MU), whose major virulence factor is mycolactone. Although early infection can be treat...ed with antibiotics, an effective preventative strategy is challenging due to unknown reservoir(s) and unresolved mode(s) of transmission.
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It is estimated that, in Latin America alone, between 6 and 8 million people are infected with the parasite, and 99% of these are not receiving treatment, either because they are unaware of their infection or because they do not know that treatment exists. The potential spread of the disease is also... a cause for considerable concern: 65 million people live in areas of exposure and are at risk of contracting Chagas disease, and 28,000 new cases occur every year.
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Advice and guidance on the health needs of migrant patients for healthcare practitioners.
Chagas disease is increasingly reported in Latin American migrants who have settled in Europe. It has rarely been reported in the UK due to lack of testing and awareness.
Chagas disease (American trypanosomia...sis) is a zoonosis caused by the flagellate protozoan parasite Trypanosoma cruzi.
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Chagas disease, or American trypanosomiasis, is an illness that can cause serious heart and stomach problems. It is caused by a parasite. Chagas disease is common in Latin America, especially in poor, rural areas. It can also be found in the United States, most often in people who were infected befo...re they moved to the U.S.
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The purpose of this document is to present concise information on the current case definitions for dengue, chikungunya, and Zika proposed by PAHO, as well as information on the clinical phases and severity classification of dengue and chikungunya.