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2
The article "Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review" analyzes factors contributing to poor asthma control in African youth. Based on studies conducted between 2014 and 2019 in Nigeria, Uganda, and South Africa, the review identifies key
...
challenges such as limited access to asthma diagnosis, inadequate use of inhaled corticosteroids, and environmental and socio-economic factors. It finds that urban living, older age, and concurrent allergic conditions significantly affect asthma management. The study emphasizes the need for improved diagnostic tools, better access to treatment, and tailored public health interventions to enhance asthma outcomes in African children.
more
Under- and over-diagnosis of COPD: a global perspective
Ho T., Cusack R.P., Chaudhary N. et al.
Breathe, part of the European Respiratory Society (ERS)
(2019)
CC2
The article "Under- and over-diagnosis of COPD: a global perspective" reviews the worldwide variation in the prevalence of chronic obstructive pulmonary disease (COPD) and issues related to its misdiagnosis. It highlights that COPD is under-diagnosed due to factors such as limited access to spiromet
...
ry and variable diagnostic criteria, especially in low- and middle-income countries. Conversely, over-diagnosis often results from reliance on non-standard criteria or inadequate spirometry use. The article discusses key risk factors, including age, gender, exposure to pollutants, and comorbidities, and emphasizes the need for standardized diagnostic practices to better address and manage COPD globally.
more
Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review
Iheanacho, I.; Zhang, S.; King, D.; et al.
International Journal of Chronic Obstructive Pulmonary Disease
(2022)
CC2
The article "Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review" examines the financial impact associated with moderate-to-very severe COPD. The review analyzes studies published between 2006 and 2016 that discuss healthcare resource utilization (HRU), di
...
rect costs, and indirect costs related to COPD, with a focus on Europe and North America. It highlights that direct costs, including hospitalizations and medical treatments, increase with the severity of COPD and the frequency of exacerbations. Multivariate analyses identify key factors driving these costs, such as comorbidities and prior treatment history. The findings underscore the significant economic burden of COPD on healthcare systems and emphasize the need for improved management strategies to reduce costs and optimize patient care.
more
The article presents findings from the BREATHE study, which assessed the distribution of COPD-related symptoms in the Middle East and North Africa (MENA) region. The study involved a large cross-sectional survey in 11 countries, collecting data on respiratory symptoms, smoking habits, and potential
...
COPD prevalence in adults aged 40 and older. Results showed that 14.3% of the surveyed population reported symptoms consistent with COPD, with variations across countries. Women reported symptoms more frequently than men, though diagnosed COPD was more common in men. The study highlighted smoking, including waterpipe use, as significant risk factors and called attention to underdiagnosed COPD in the region, emphasizing the need for increased awareness and better diagnostic practices.
more
Chronic obstructive pulmonary disease in sub-Saharan Africa
Awokola, B.I.; Amusa, G.A.; Jewell, C.P.; et al.
International Journal of Tuberculosis and Lung Disease
(2022)
CC2
The article provides a systematic review and meta-analysis of the prevalence and risk factors of chronic obstructive pulmonary disease (COPD) in sub-Saharan Africa (SSA). It highlights that COPD is a significant cause of morbidity and mortality in the region, with prevalence rates ranging from 1.7%
...
to 24.8% and an average pooled prevalence of 8%. The analysis points out that smoking, exposure to biomass smoke, and age are key risk factors. The study emphasizes the need for improved diagnosis and awareness, as COPD often remains underdiagnosed and undertreated in SSA. The authors call for coordinated efforts from clinicians, researchers, and policymakers to address these issues and reduce exposure to preventable risk factors.
more
The article investigates the diagnostic capabilities and prevalence of chronic obstructive pulmonary disease (COPD) in primary care settings in northern Brazil. It highlights that COPD is often underdiagnosed and undertreated in resource-limited regions. The study involved 34 general practitioners a
...
nd used spirometry to evaluate their diagnostic accuracy compared to clinical assessments. Findings revealed significant discrepancies between GP diagnoses and spirometry results, with many false positives and negatives. The study underscores the need for better training and the use of spirometry to improve COPD diagnosis and case-finding in primary care, emphasizing the importance of targeted strategies to enhance healthcare outcomes in developing countries.
more
The article examines the epidemiology of chronic obstructive pulmonary disease (COPD) in the Middle East, North Africa, and Turkey. It provides an overview of COPD prevalence, associated risk factors, and challenges in diagnosis and treatment across these regions. The study highlights smoking and en
...
vironmental exposures, such as dust and pollution, as significant contributors to COPD. It also points out the gaps in awareness, healthcare infrastructure, and the availability of diagnostic tools, which hinder effective management of the disease. The authors emphasize the need for comprehensive public health strategies, education, and improved access to healthcare to address the COPD burden in these areas.
more
The article analyzes the prevalence and risk factors of chronic respiratory diseases, focusing on sub-Saharan Africa. It highlights that environmental exposures, such as biomass fuel usage and air pollution, significantly contribute to respiratory health issues in the region. The research underlines
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the limited healthcare infrastructure, insufficient diagnostic tools, and the need for comprehensive data collection to better understand the burden of respiratory diseases. The authors advocate for targeted public health interventions, improved access to healthcare, and policies aimed at reducing exposure to risk factors to mitigate the prevalence of respiratory conditions.
more
The article investigates the effectiveness and challenges of remote monitoring systems for chronic respiratory diseases, focusing on COPD and asthma. It reviews various technologies and their potential to improve patient outcomes through better symptom tracking, medication adherence, and early detec
...
tion of exacerbations. The study highlights that while remote monitoring has significant potential, challenges such as data accuracy, patient compliance, and integration with existing healthcare systems remain. The authors call for further research to standardize and validate remote monitoring tools and emphasize the need for patient-centric approaches to enhance engagement and adherence.
more
Global Alliance against Chronic Respiratory Diseases (GARD) Brazil success case: overcoming barriers
Cruz, A.A.; Camargos, P. A.; Urrutia-Pereira, M.; Stelmach, R.
Journal of Thoracic Disease
(2018)
CC2
The article discusses the success of the Global Alliance against Chronic Respiratory Diseases (GARD) in Brazil. It details the initiatives launched to address chronic respiratory diseases (CRDs) like asthma and COPD, emphasizing the development of national programs and collaborative efforts with the
...
World Health Organization (WHO). Key achievements include successful advocacy, education campaigns, and pilot projects for asthma control, which have led to improved access to treatment and better management of CRDs. Despite challenges such as limited government priority, GARD Brazil has made significant progress in awareness and care for respiratory conditions. The article highlights the need for continued support to sustain these efforts and develop a formal national action plan.
more
The article outlines the prioritized research agenda for the prevention and control of chronic respiratory diseases (CRDs) as part of the World Health Organization's (WHO) action plan on noncommunicable diseases (NCDs) from 2008 to 2013. It highlights the significant global impact of CRDs, including
...
asthma, chronic obstructive pulmonary disease (COPD), and other related conditions, particularly in low- and middle-income countries (LMICs). The document stresses the need for effective prevention strategies and better surveillance, as well as enhanced healthcare infrastructure and resources in LMICs. It calls for research into CRD risk factors, effective interventions, and integrated care approaches that align with broader NCD prevention programs. The article emphasizes the importance of public health initiatives and cross-sector collaborations to reduce the disease burden and improve patient outcomes.
more
The webpage from the Pan American Health Organization (PAHO) focuses on the significant health impacts of air pollution in the Americas. It explains how exposure to air pollutants contributes to various health issues, including respiratory and cardiovascular diseases, leading to premature deaths. Th
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e site highlights key sources of air pollution, such as vehicle emissions, industrial activities, and household energy use. PAHO emphasizes the need for effective public health policies, cross-sector collaboration, and sustainable practices to reduce pollution levels and protect public health in the region.
more
The article from the European Respiratory Journal discusses the natural history of chronic obstructive pulmonary disease (COPD), emphasizing its increasing global impact on morbidity and mortality. It highlights that while cigarette smoking is a primary risk factor, other influences such as environm
...
ental exposures and genetics also play significant roles. The article notes that lung function, measured by FEV1 (forced expiratory volume in one second), is a critical indicator of both diagnosis and prognosis. It further explores the impact of exacerbations, comorbidities, and systemic inflammation on disease progression and outcomes. The need for comprehensive patient management, which considers various comorbid conditions and inflammatory factors, is emphasized to improve clinical outcomes and reduce healthcare costs.
more
The article discusses the significant impact of chronic obstructive pulmonary disease (COPD) as a global health issue, with cigarette smoking as the main risk factor. However, in developing countries, the causes of COPD are often multifactorial, involving environmental tobacco smoke, biomass fuel sm
...
oke, dust, fumes, childhood illnesses, and tuberculosis (TB). Up to half of COPD patients in these regions are non-smokers. The article emphasizes that while smoking is crucial, other risk factors contribute significantly to COPD, particularly in low- and middle-income countries. It highlights the need for targeted research and public health strategies to address these diverse contributors to COPD, especially in Africa.
more
The article discusses chronic obstructive pulmonary disease (COPD) as a common but under-recognized occupational disease. While smoking is the main cause, occupational exposure to vapors, gases, dusts, and fumes (VGDF) significantly contributes to the development and progression of COPD. Epidemiolog
...
ical studies indicate that up to 14% of COPD cases are attributable to occupational factors. The article highlights the need for better physician training in obtaining occupational exposure histories and emphasizes early diagnosis to prevent disease progression. Additionally, it stresses the importance of collaboration among general practitioners, respiratory specialists, and occupational health professionals to reduce the health and socio-economic impact of COPD.
more
The document titled "Early Warning Signs of COPD" from the American Lung Association outlines what COPD is, its risk factors, and the importance of recognizing early symptoms such as persistent cough, breathlessness, and frequent chest infections. It emphasizes the
...
need for early consultation with a healthcare provider and diagnostic testing like spirometry to confirm COPD. Early diagnosis and treatment can help slow disease progression and improve quality of life.
more
The aim of the GOLD Report is to provide a non-biased review of the current evidence for the assessment, diagnosis and treatment of people with COPD. One of the strengths of GOLD reports is the treatment objectives. These have stood the test of time, and are organized into two groups: objectives tha
...
t are directed towards relieving and reducing the impact of symptoms, and objectives that reduce the risk of adverse health events that may affect the patient at some point in the future (exacerbations are an example of such events). This emphasizes the need for clinicians to focus on both the short-term and long-term impact of COPD on their patients.
more
The Asthma Control Questionnaire (ACQ)1 was developed and validated to measure the primary clinical goal of asthma management as identified by international guidelines. They indicate that to achieve good control, treatment should minimise day and night time symptoms, activity limitation, airway narr
...
owing and rescue bronchodilator use and thus reduce the risk of life-threatening exacerbations and long-term morbidity. The importance of including all aspects of control in the assessment of individual patients was emphasised by a recent factor analysis which showed that clinical asthma is composed of distinct components which are not closely correlated with each other.6 However, in some studies it may not be possible to collect airway calibre or short-acting β2-agonists data. Previous analysis of non-clinical trial data suggested that when ACQ scores are analysed as group data, the heterogeneity of the way in which individual patients present with inadequate control is lost in the estimation of the mean and the need to measure each individual component of asthma control may become unnecessary. In this analysis, ACQ data from a clinical trial was used to evaluate the measurement properties (reliability, responsiveness, validity and interpretability), of three shortened versions of the ACQ. In addition, we have examined whether the precision and accuracy of estimating the effect of the intervention on asthma control was maintained when the two questions concerning airway calibre and short-acting β2-agonists use were omitted from the trial analysis.
more
A worldwide increase in the prevalence of asthma has been reported in recent years. With an increase in prevalence comes an increased burden of disease in terms of morbidity, mortality and compromised quality of life. The economic burden in terms of utilisation of healthcare resources and limitation
...
of the earning capacity of the individuals and families is an added problem. Various indicators such as disability-adjusted life years and healthy life years have been used to define the economic burden. The data from Asian countries regarding these parameters is scarce, underlining the need for systematic studies in these countries, especially those that are resource poor. The purpose of this review is to highlight the varying prevalence of asthma in Asia and to assess the likely economic burden for the future.
more
The National Asthma Education Programme (NAEP) is a registered non-profit organisation whose mission is to provide asthma education to healthcare professionals, patients and the lay public. It was founded in 1994 by Dr Mike Greenblatt and Profs Dave Luyt and Robin Green. This year NAEP celebrates it
...
s 25th anniversary and remains driven by the need to improve the daily lives of numerous asthmatics in South Africa (SA) and Africa.
more
