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About one fourth of the world’s population is estimated to have been infected with the tuberculosis (TB) bacilli, and about 5–10% of those infected develop TB disease in their lifetime. The risk
...
for TB disease after infection depends on several factors, the most important being the person’s immunological status. TB preventive treatment (TPT) given to people at highest risk of progressing from TB infection to disease remains a critical element to achieve the global targets of the End TB Strategy, as reiterated by the second UN High Level Meeting on TB in 2023. Delivering TPT effectively and safely necessitates a programmatic approach to implement a comprehensive package of interventions along a cascade of care: identifying individuals at highest risk, screening for TB and ruling out TB disease, testing for TB infection, and choosing the preventive treatment option that is best suited to an individual, managing adverse events, supporting medication adherence and monitoring programmatic performance.
more
About one fourth of the world’s population is estimated to have been infected with the tuberculosis (TB) bacilli, and about 5–10% of those infected develop TB disease in their lifetime. The risk
...
for TB disease after infection depends on several factors, the most important being the person’s immunological status. TB preventive treatment (TPT) given to people at highest risk of progressing from TB infection to disease remains a critical element to achieve the global targets of the End TB Strategy, as reiterated by the second UN High Level Meeting on TB in 2023. Delivering TPT effectively and safely necessitates a programmatic approach to implement a comprehensive package of interventions along a cascade of care: identifying individuals at highest risk, screening for TB and ruling out TB disease, testing for TB infection, and choosing the preventive treatment option that is best suited to an individual, managing adverse events, supporting medication adherence and monitoring programmatic performance
more
Skin and mucosal conditions are extremely common in all children and adults in particular in HIV-infected adults and children and are one of the commonest daily management problems faced by health care workers caring for patients with HIV infection
"Our findings provide a quantitative estimate of the risk of microcephaly in fetuses and neonates whose mothers are infected with Zika virus."
Published Online: 15 March 2016, http://dx.doi.org/10.1016/S0140-6736(16)00651-6
Please download this
...
article directly from the webpage: http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736%2816%2900651-6.pdf
more
Onchocerciasis – or “river blindness” – is a parasitic disease caused by the filarial worm Onchocerca volvulus transmitted by repeated bites of infected blackflies (Simulium spp.). These blackflies breed along fast-flowing rivers and streams
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, close to remote villages located near fertile land where people rely on agriculture.
more
Over 2 million children worldwide are living with HIV infection and 95% reside in sub-Saharan Africa with the majority infected through mother-to-child transmission. Infected children have a high mo
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rtality with 50% dying by 2 years of age. Their clinical presentation includes common childhood infections, opportunistic infections and conditions associated with HIV/AIDS immune suppression.
more
A recent study informed that ivermectin was successfully used in vitro for the treatment of SARS-CoV-2 in experimentally infected cells and two preprint publications on observational clinical studies reported the apparent utility of ivermectin to tr
...
eat patients with COVID-19 needing mechanical ventilation. However, neither of these studies were peer-reviewed nor formally published and one of them was later retracted.
more
COVID-19 outbreak is associated with the generation of many types of infectious wastes, including infected masks, gloves and other protective equipment, together with a higher volume of general waste of the same nature.
It is estimated that, in Latin America alone, between 6 and 8 million people are infected with the parasite, and 99% of these are not receiving treatment, either because they are unaware of their infection or because they do not know that treatment
...
exists. The potential spread of the disease is also a cause for considerable concern: 65 million people live in areas of exposure and are at risk of contracting Chagas disease, and 28,000 new cases occur every year.
more
There are currently 4 different serotypes of Dengue virus known to science. Each time someone get infected and recovers, the individual will be protected by a lifelong immunity from further infection against that specific serotype and that serotype
...
only.
Consequent infection from different serotype not only will infect the individual but may also cause a more serious or severe disease progression.
more
Leishmaniasis is a parasitic disease caused by the Leishmania parasite. This parasite typically lives in infected sand flies. You can contract leishmaniasis from a bite of an infected sand fly.
T
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he sand flies that carry the parasite typically reside in tropical and subtropical environments. Fatal epidemics have occurred in areas of Asia, East Africa, and South America.
Affected regions are often remote and unstable, with limited resources for treating this disease. Doctors Without Borders calls leishmaniasis one of the most dangerous neglected tropical diseases. The organization also states this disease is second only to malaria in parasitic causes of death.
more
Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and
blindness. But the epidemiological situation h
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as improved dramatically over the last two decades. Community directed treatment with ivermectin has effectively brought the disease under control in most endemic areas where onchocerciasis is no longer a public health risk.
more
Foodborne trematodiases are caused by parasitic trematode worms. People become infected by eating raw or undercooked fish, crustaceans and vegetables that contain the larval worms.
Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the ende
...
mic areas in sub-Saharan Africa. HAT transmission last soared in the late 1990s, triggering a renewed, coordinated and very successful control effort. In this paper, we present achievements towards HAT elimination, with a focus on the WHO road map targets for 2020. In particular, reported cases continue to decline, from over 30,000 cases per year at the turn of the century to 663 cases in 2020. Despite the impact of the COVID-19 pandemic, HAT surveillance was largely sustained, and the network of health facilities able to diagnose and treat the disease further expanded. Looking to the future, the World Health Organization (WHO) set bold new targets for HAT in its 2021–2030 road map for NTDs, namely: the elimination of transmission of gambiense HAT, which occurs in western and central Africa, and the elimination as a public health problem of rhodesiense HAT, which is found in eastern and southern Africa. The strong commitment of national health authorities and the international community will be essential if these goals are to be achieved.
more
Rabies is a rare but serious infection that's usually caught from a bite or scratch of an infected animal. It's almost always fatal once symptoms appear, but vaccination and early treatment can prevent it.
In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-
...
infected pregnant and breastfeeding women be offered treatment, with praziquantel, either individually or during treatment campaigns. In 2006, WHO also stated the need for randomized controlled trials to assess the safety and efficacy of such treatment. Some countries have yet to follow the recommendation on treatment and many programme managers and pregnant women in other countries remain reluctant to follow the recommended approach.
more
Soil-transmitted helminth (STH) infections are among the most common infections worldwide with an estimated 1.5 billion infected people or 24% of the world’s population. These infections affect the poorest and most deprived communities with poor a
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ccess to clean water, sanitation and hygiene in tropical and subtropical areas, with the highest prevalence reported from sub-Saharan Africa, China, South America and Asia. They are transmitted by eggs present in human faeces, which in turn contaminate soil in areas where sanitation is poor. Over 260 million preschool-age children, 654 million school-age children,108 million adolescent girls and 138.8 million pregnant and lactating women live in areas where these parasites are intensively transmitted, and are in need of treatment and preventive interventions.
more
Interim Assessement Report
The EMA review was started by the Agency’s Committee for Medicinal Products for Human Use (CHMP) to support decision-making by health authorities. This first interim report includes information on seven experimental medicines intended for the treatment of people
...
infected with the Ebola virus:
BCX4430 (Biocryst);
Brincidofovir (Chimerix);
Favipiravir (Fujifilm Corporation/Toyama);
TKM-100802 (Tekmira);
AVI-7537 (Sarepta);
ZMapp (Leafbio Inc.);
Anti-Ebola F(ab’)2 (Fab’entech).
The amount of information available for the seven treatments is highly variable. For some compounds there is no data from use in human subjects available. A small number of treatments have been administered to patients in the current Ebola outbreak as compassionate use. Finally, there are also medicines included in this review that have already been studied in humans, albeit for the treatment of other viral diseases.
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I SURVIVED EBOLA:THANKS TO ASEOWA
Alimatou Camara Speaks of her battle with Ebola and of the Care she received at the ASEOWA run Ebola Treatment Unit in Guinea
Guinean Alimatou Camara, a seventeen year old housewife in a polygamous union, lost her mother in-law, her only daughter and her stepdau
...
ghter to Ebola. She got infected too, but survived, thanks to the African Union Support to Ebola Outbreak in West Africa (ASEOWA).
By Lilas Belepe,
Communication Officer, ASEOWA Guinee
A resident of Forécariah, a town situated one hundred kilometres away from Conakry, the capital of Guinea, she narrates the ordeal that befell her and her family, her battle with Ebola and the time she spent recovering at the African Union run Ebola Treatment Unit (ETU), in Coyah.
more
The flip book is for pre-deployment trainings for Ebola response, and is based on frequently asked questions about Ebola virus disease (EVD):
What is Ebola virus disease?
How do people become infected with EVD?
Why WHO is focusing on
...
safe and dignified burials of people who have died from Ebola?
Who is most at risk?
What are the symptoms of Ebola infection?
What treatment is available for Ebola?
more
