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Rabies is a fatal viral disease, but is preventable in humans. The rabies virus is transmitted to humans through virus-laden saliva from a rabid animal, mostly dogs. The virus is shed in the saliva of an infected animal and can be introduced into another body through bites, scratches and any other ... more
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Diretrizes para Diagnóstico e Tratamento da COVID-19 (Guidelines for Diagnosis and Treatment of COVID-19)
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A elaboração das Diretrizes para Diagnóstico e Tratamento da COVID-19 é uma resposta rápida ao enfrentamento da COVID-19, diante da declaração de pandemia pela Organização Mundial de Saúde (OMS) e das iniciativas do Ministério da Saúde para enfrentamento dessa nova situação no Brasil. ... more
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Report of a WHO–FIND meeting on diagnostics for Buruli ulcer

World Health Organization WHO Tecnical Advisory Group and FIND (2018) CC
The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rapid diagnostic tests (RDTs) targeting the MUL... more
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Recommendations for national SARS-CoV-2 testing strategies and diagnostic capacities
recommended

World Health Organization WHO (2021) C_WHO
Interium guidance, 25 June 2021Timely and accurate diagnostic testing is an essential tool in preventing and controlling the spread of COVID-19. This document describes recommendations for national testing strategies and the use of PCR and rapid antigen tests in different transmission scenarios of t... more
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Paludisme : présentation clinique, diagnostic et traitement. Version pour professionels de la santé

Marie C., Petri W. A. jr. Le Manuel MSD (2023) C2
La page du Manuel MSD Professionnel consacrée au paludisme présente une synthèse complète de cette maladie parasitaire grave causée par des protozoaires du genre Plasmodium, transmis par les piqûres de moustiques Anopheles. Elle décrit les différentes espèces responsables, les cycles de vie... more
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Implications of the COVID-19 pandemic for patient safety: a rapid review

World Health Organization WHO (2022) C_WHO
The pandemic has emphasized the high risk of avoidable harm to patients, health workers, and the general public, and has identified a range of safety gaps across all core components of health systems at all levels. The rapid review ‘Implications of the COVID-19 pandemic for patient safety’ ex... more
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Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy

World Health Organization (WHO) (2017) C_WHO
The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all people living with HIV.
WHO recommends that a... more
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Multiple first-line therapies as part of the response to antimalarial drug resistance

World Health Organization WHO (2024) C_WHO
Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisinin for rapid parasite reduction with a partner drug ... more
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Validación e implementación de GeneXpert MTB/RIF para diagnóstico de tuberculosis en Ecuador

Ortiz-Jiménez; J.; G. Franco-Sotomayor; M. Ramos-Ramirez Kasmera (2019) CC
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In... more
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Laboratory biosafety guidance related to coronavirus disease (COVID-19): Interim guidance, 28 January 2021
recommended

World Health Organization WHO (2021) C_WHO
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decontamination before disposal; personal protectiv... more
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Orientaciones sobre la bioseguridad en el laboratorio relacionada con la COVID-19
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Organización Mundial de la Salud OMS (2021) C_WHO
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decontamination before disposal; personal protectiv... more
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WHO recommends countries move away from the use of western blotting and line immunoassays in HIV testing strategies and algorithms. Policy brief

World Health Organization WHO (2019) C_WHO
WHO recommends replacing western blotting and line immunoassays with simpler tests in HIV testing services. These simpler tests include rapid diagnostic tests (RDTs) that can be used at the point-of-care, and enzyme immunoassays (EIAs). These tests get results to the client faster, produce accura... more
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Практическое руководство по биологической безопасности в лабораторных условиях в связи с коронавирусной инфекцией (COVID-19)
recommended

World Health Organization WHO (2021) C_WHO
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decontamination before disposal; personal protectiv... more
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Cochrane COVID-19 Study Register

Cochrane Library (2020) CC
The aim of the register is to support rapid evidence synthesis by all systematic review producers, including Cochrane's work on Rapid Reviews in response to COVID-19. The register helps systematic reviewers prioritize topics, identify available evidence, and produce urgently needed reviews for front... more
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Guidelines for management of co-infection of COVID-19 with other seasonal epidemic prone diseases

Government of India Ministry of Health & Family Welfare Directorate General of Health Services (EMR Division) (2025) CC2
The ongoing global pandemic of SARS-CoV-2 (Covid-19) poses unique diagnostic and clinical management challenges in regions where seasonal epidemic-prone diseases are endemic. Diseases such as dengue, malaria, seasonal influenza, leptospirosis, chikungunya, scrub typhus and bacterial infections often... more
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Policy on TB Control in Health Care Facilities, Congregate Settings and Households

World Health Organization WHO (2009)
This document is an evidence-based policy for the implementation of sound tuberculosis (TB) infection control by all stake- holders. It recommends a combination of measures aimed at reducing the risk of TB transmission within populations. The emphasis is on early and rapid diagnosis, and proper mana... more
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Cancer in sub-Saharan Africa
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Ngwa, W.; et al. Lancet Oncology Commission (2022) C2
Lancet Oncol 2022; 23: e251–312Published OnlineMay 9, 2022 https://doi.org/10.1016/S1470-2045(21)00720-8 In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality. Without rapid interventions, data estimates show a major increase in cancer mo... more