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It is against this background that the Ministry of Health and Sanitation with its partners have taken the lead to develop Essential Health Services Package (EHSP). The MOHS believes that the development of EHSP; defining the services that should be available at each level of care (community to ... more
In Sierra Leone, Health care delivery is organized around a three-tier system i) primary level constituting peripheral health units (community health centers, community health posts, and maternal and child health posts secondary level constituting district hospitals tertiary level comprising region ... more
Guidelines approved by the WHO Guidelines -Review Committee; second edition
Mpox, previously known as monkeypox, is a viral illness caused by the monkeypox virus (MPXV).1 It causes a painful rash, enlarged lymph nodes, fever, headache, muscle ache, back pain and low energy or feeling sick. In most cases, the symptoms of mpox go away within a few weeks with supportive care ... more
In this subsequent part of the issue brief on the NTD Toolbox you will learn about general strategies, roadmaps, key treatment guidelines, reports, and training material on Schistosomiasis
The rapid assessment tool (RAT) is meant to assess health facilities within mpox-affected areas that have at least one inpatient bed. Depending on time and resources available, certain facilities may be prioritized during an mpox outbreak. The RAT evaluates 16 infection prevention and control (IPC) ... more
PLoS ONE 17(9): e0272444. https://doi.org/ 10.1371/journal.pone.0272444. Based on the RE-AIM metrics, our results show that KMC is a feasible intervention that can improve neonatal outcomes among preterm infants in Zambia. The study findings show a promising, practical approach to scaling up KMC in ... more
PLoS ONE 18(5): e0285031. https://doi.org/10.1371/journal.pone.0285031 The study aims to integrate HPV vaccination into routine care in adolescent HIV clinics. To achieve success, we will co-design a package of implementation strategies using a previously successful implementation research approach ... more
Lessons learned from recent public health events such as the COVID-19 pandemic, Ebola virus disease, Zika virus disease outbreaks, and other public health threats, including earthquakes and floods, have highlighted the need for countries to continuously develop, strengthen, and maintain capacities r ... more
A review of prospects for existing antibiotics ad new therapeutics
Journal of Computational Biophysics and ChemistryVol. 22, No. 01, pp. 31-41 (2023)
Buruli ulcer (BU), a neglected tropical disease (NTD), is an infection of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. The disease has been documented in many South American, Asian, and Western Pacific countries and is widespread throughout much of Africa, especially in West ... more
The aim of the meeting was to broaden the network’s initiatives. Preliminary work involved integrating laboratory testing for skin NTDs other than Buruli ulcer, such as cutaneous leishmaniasis, mycetoma, leprosy and yaws, while extending the network’s reach to encompass additional laboratories.
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti ... more
Having established the goal of eliminating transmission of gambiense human African trypanosomiasis (g-HAT) to humans, the HAT-e-TAG considered which elements should be developed to assess this goal.
Tsetse traps and targets (insecticide-impregnated screens) function by attracting the flies to a device that collects and/or kills them. Traps can be used for entomological surveillance, and also for control. Targets are simpler than traps, but are not used for surveillance. They are impregnated wit ... more
The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
3rd edition
Trachoma is the leading infectious cause of blindness worldwide. In April 2023, it was a public health problem in approximately 40 countries, with an estimated 116 million people at risk and 1.5 million people affected by the late blinding stage of the disease (1). About 84% of those at risk of tr ... more
The WHO Vision and eye screening implementation handbook (VESIH) offers a step-by-step guidance for conducting vision and eye screenings in community and primary care settings. The evidence-based interventions are drawn from the WHO Package of eye care interventions and developed with a focus on del ... more