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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Philippines: MNCHN Strategy Manual of Operations

Depar tment of Health, National Center for Disease Prevention and Control (2011) C1

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Comprehensive Action Plan for Afghanistan and neighbouring countries AUG 2021 - DEC 2024

International Organization for Migration IOM (2021) CC

The International Organization for Migration (IOM) is appealing for USD 158.9 million to respond to the urgent humanitarian needs of millions of Afghans and to support recovery and resilience within the country and the region. IOM’s Comprehensive Action Plan for Afghanistan and Neighbouring Cou... more

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Costed Regional Action Plan to End Cross-Border Female Genital Mutilation

UNFPA ESARO UNFPA ESARO (2022) CC

This regional action plan provides a broad framework for the regional level to assist governments in accelerating the implementation of existing international, regional and national commitments on ending FGM. Formulating the plan has provided an opportunity for the region to identify broad prioritie... more

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Planning Checklist for WCO Readiness

World Health Organization WHO (2017) C_WHO

This guidance has been developed in line with the WHO corporate risk management framework, the WHO business continuity and contingency plans, as well as the Inter-Agency Emergency Response Preparedness Framework. It is based on a common organiza-tional approach and procedures for managing including ... more

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Malawi: 2019 Flood Response Plan and Appeal

Government of Malawi (2019) C2

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COVID-19 Emergency Response Plan

OCHA; Reliefweb; World Vision OCHA; Reliefweb; World Vision (2020) C2

April 3, 2020

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U.S. Government Global Nutrition Coordination Plan 2021-2026 - World

US Agency for International Development (2021) C2

English Manual and Guideline on World about Food and Nutrition, Health and Epidemic; published on 30 Nov 2021 by USAID

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Plan de acción mundial sobre la resistencia a los antimicrobianos

World Health Organisation (WHO) (2016) C_WHO

dades infecciosas. Los antimicrobianos eficaces son imprescindibles para las medidas preventivas y curativas, para proteger a los pacientes frente a enfermedades potencialmente mortales y para garantizar que se puedan llevar a cabo procedimientos complejos, como la cirugía y la quimioterapia, con e... more

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Планирование и бюджетирование услуг в области психического здоровья

Alan J. Flisher, Michelle Funk, Natalie Drew et al. World Health Organization (2007) C_WHO

Свод методических рекомендаций состоит из нескольких тематически связанных и удобных для пользователя модулей для решения широкого спектра задач и приоритетных ... more

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Malawi national action plan on antimicrobial resistance: review of progress in the human health sector

World Health Organization WHO (2022) C_WHO

This policy brief aims to provide a review of the current progress on implementing the Malawi national action plan on AMR, identifies critical gaps, and highlights findings to accelerate further progress in the human health sector. The target audience includes all those concerned with implementing a... more

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DFID’s Strategy for Disability Inclusive Development 2018-23

Department for International Development DFID UKaid (2018) C1

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National surgical, obstetric and anesthesia plan 2018-2024

Ministry of Health, Rwanda (2018) CC

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Kenya: National Strategic Plan on Tuberculosis, Leprosy and Lung Health 2019-2023

National Tuberculosis Leprosy and Lung Disease Program (NTLD-program), Ministry of Health, Republic of Kenya (2019) C2

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Pakistan: AMR National Action Plan 2017

Ministry of National Health Services Regulations & Coordination Government of Pakistan (2017) C2

The increasing global trend of Antimicrobial resistance (AMR) has gradually emerged as a major public health challenge for the entire world. AMR has spread to almost all countries and regions, including Pakistan owing to the “misuse and overuse” of Antimicrobials, contributing to the increasing ... more

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National Action Plan for Combating Antimicrobial Resistance In the Hashemite Kingdom of Jordan (2018-2022)

Ministry of Health Jordan (2018) C_WHO

The objectives of NAP are aligned with the global action plan based on national needs and priorities. The emphasis is on One Health approach with all sectors especially human health, animal health and environment contributing towards minimizing the emergence and impact of AMR in Jordan.

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Guide for Implementing the Monitoring-Training-Planning (MTP) Approach to Build Skills for Pharmaceutical Management

Rational Pharmaceutical Management Plus Program Management Sciences for Health; USAID (2009) CC

In the mid-1980s, recognizing the limitations of traditional training and that the knowledge and skills acquired are not necessarily applied back in the workplace, MSH developed the Monitoring‐Training-Planning (MTP) approach to assist the Ecuadorian Ministry of Health to implement its Child Survi... more

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Rwanda HIV and AIDS National Strategic Plan (July 2013 - June 2018)

Ministry of Health, Rwanda & Rwanda Biomedical Centre (2013) C2

During the implementation of the National Strategic Plan 2009–2012 on HIV and AIDS, Rwanda has continued its progress towards universal access to HIV and AIDS services. The new HIV and AIDS National Strategic Plan July 2013–June 2018 (thereafter referred to as ‘the NSP’) presented here is se... more

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National Implementation Plan/ National Disability Mainstreaming Plan

Bedding, E.J.; M. Banda-Chalwe; T. Mtonga (2013) C1

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South Sudan Response Plan April 2020–March 2021

Food and Agriculture Organization of the United Nations FAO (2020) CC

Previous crises, such as the Ebola virus disease (EVD) in West Africa in 2014, indicate the direct impact movement restrictions and disease containment efforts have on food availability, access, utilization and violence – particularly gender-based violence (GBV). The importance of maintaining and ... more