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The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P ... more
La thèse de Yobouet Inès Kouakou, soutenue à l’Université Claude Bernard Lyon 1, porte sur le traitement d’urgence du paludisme sévère chez l’enfant à l’aide d’une administration intranasale d’artésunate. L’objectif principal de ce travail est d’explorer, in vitro, la voie na ... more
Preferred product characteristics and clinical development considerations
The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever. An integrated approach is vital, as these four diseases often present with similar symptoms, especially in the early stages ... more
Addressing TB comorbidities and risk factors is central to the World Health Organization (WHO) End TB Strategy. These guidelines consolidate the latest WHO recommendations on TB and key comorbidities. The guidelines are a living document and will include dedicated sections for each key TB comorbidit ... more
National Guidelines
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV document is published in an electronic format and updated as relevant changes in prevention and treatment recommendations occur.
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is highly dep ... more
Pathogens 2022, 11, 33. https://doi.org/10.3390/pathogens11010033
A Training Curriculum
a comprehensive guide for the HCPs who work in counselling and psychological care of children and adoles- cents. The Handbook includes information on HIV clinical care; growth and development; mental health; child protection; counselling and communication; disclosure; loss, grief, and bereavemen ... more
These guidelines focus on the provision of PrEP as part of comprehensive combination prevention, drawing on implementation and research evidence and WHO recommendations.
This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu ... more
2020 Version