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LEPTOSPIROSIS Fact Sheet for Clinicians

Center for Disease Control and Prevention CDC (2018) CC

• Leptospirosis is a disease that is caused by spirochete bacteria in the genus Leptospira. There are 10 pathogenic species, and more than 250 pathogenic serovars. • While leptospirosis occurs worldwide, it is more common in tropical or sub-tropical climates.

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Outcomes of Universal Access to Antiretroviral Therapy (ART) in Georgia

T. Tsertsvadze; N. Chkhartishvili; L. Sharvadze; et al. Hindawi Publishing Corporation AIDS Research and Treatment (2011) C2

Research Article Hindawi Publishing Corporation AIDS Research and Treatment Volume 2011, Article ID 621078, 7 pages doi:10.1155/2011/621078

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Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) Country Report Malawi

Africa Center for Disease Control and Prevention (2023) CC

The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project has conducted a multi-year, multi-country study that provides stark insights on the under-reported depth of the antimicrobial resistance (AMR) crisis across Africa and lays out urgent policy recommendations to addr... more

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Integrated Biological and Behavioral Surveillance (IBBS) Survey among Female Sex Workers in 22 Highway Districts of Nepal, Round VI 2016

National Center for AIDS and STD Control (2016) C1

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Interim Guidance for a Public Health Response to Contain Novel or Targeted Multidrug-resistant Organisms (MDROs)

Center for Disease Control and Prevention CDC (2019) C_CDC

This document is intended for use by state and local health departments and healthcare facilities and serves as general guidance for the initial response for the containment of novel or targeted multidrug-resistant organisms (MDROs) or resistance mechanisms. It is not intended to describe all the ac... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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North Macedonia

L. Savikj European Monitoring Centre for Drugs and Drug Addiction (2013) C2

A summary of the national drug situation

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Essential health care service disruption due to COVID-19: lessons for sustainability in Nigeria

AHOP National Centre based in Nigeria World Health Organization WHO, Regional Office Africa (2022) C_WHO

The brief concludes that sustaining the continuity of EHS requires policies that ensure a whole-society and systems strengthening approach. This involves increased health care investment, community engagement, disease control regulations, and multisector approaches to improve resilience, EHS quality... more

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Nigeria: Preparedness and Response to Acute Watery Diarrhoea Outbreaks

Federal Ministry of Health - Nigeria Centre for Disease Control (2017) C2

A GUIDE FOR HEALTH WORKERS AND AUTHORITIES IN NIGERIA

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"Out of the shadows" : a qualitative study of parents’ and professionals’ attitudes and beliefs about children with communication disability in Uganda and how best to help them

McGeown, J. Centre for International Health and Development (2012) CC

Dissertation submitted in part fulfilment of the requirements for a Masters degree at the Centre for International Health and Development (CIHD) at University College London (UCL) Institute of Child Health (ICH) The user has given permission for the uploaded document to be reproduced and made publi... more

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Timor-Leste: Disaster Management Reference Handbook

Center for Excellence in Disaster Management and Humanitarian Assistance (2016) C1

Timor-Leste’s vulnerability to natural hazards means if particular care is not taken in the development of the country’s infrastructure, it will remain at risk to disruption.
Timor-Leste developed the 2008 National Disaster Risk Management Policy, which lays out the government’s vison of ... more

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COVID-19: Training slides based on guidelines for case-finding, diagnosis, management and public health response in South Africa

Centre for Respiratory Diseases and Meningitis and Outbreak Response National Department of Health, South Africa (2020) C2

Outline • Welcome and objectives • Microbiology, epidemiology and clinical presentation • Surveillance for imported cases including case definitions • Laboratory diagnosis • Infection prevention and hospital readiness • Patient flow and actions required at each step • Co-ord... more

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Myanmar (Burma): Disaster Management Reference Handbook

Center for Excellence in Disaster Management and Humanitarian Assistance (2017) C1

Myanmar has made significant progress in its disaster management policies, plans, and procedures since 2008, when Cyclone Nargis impacted the country leaving devastation in its aftermath. The Government of Myanmar (GoM) has modified the government structure and created new authorities and plans to i... more

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Bangladesh: Disaster Management Reference Handbook

Center for Excellence in Disaster Management and Humanitarian Assistance (2017) C1

Climate change is a growing concern for Bangladesh because 90 percent of the country is approximately 10 feet above sea level. An evaluation was completed which discovered that high tides in Bangladesh were increasing 10 times more rapidly than the global average. This predicted rapid increase in se... more