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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Malaria Operational Plan FY 2018 Ethiopia

United States Agency for International Development United States Agency for International Development (2018) C1

This FY 2018 Malaria Operational Plan (MOP) presents a detailed implementation plan for Ethiopia, based on the strategies of PMI and the National Malaria Control Program (NMCP). It was developed in consultation with the Federal Ministry of Health (FMOH), NMCP, Ethiopian Public Health Institute (EP... more

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Female Genital Schistosomiasis: a guide to inform equitable schistosomiasis control efforts in Ghana

Countdown (2020) CC

Learning pack. This pack presents a summary of exploratory qualitative research methods and findings from frontline health implementers and communities conducted by the research team in Ghana.

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Africa CDC: Event based Surveillance Framework

Africa CDC (2018) C_CDC

Event-based surveillance (EBS) is defined as the organized collection, monitoring, assessment and interpretation of mainly unstructured ad hoc information regarding health events or risks, which may represent an acute risk to health. Both indicator-based and event-based surveillance components serve... more

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Rwanda: EARLY CHILDHOOD DEVELOPMENT POLICY

Ministry of Education, Rwanda (2011) C2

The Early Childhood Development Policy and its Strategic Plan seek to provide a framework to ensure such a holistic and integrated approach to the development of young children. International research has demonstrated the high economic returns on ECD investment and its positive impact on health and ... more

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Evaluation of Ebola response - Uganda

Sigridur B.Thormar IFRC (2013)

The main aim of this assessment was to evaluate the PSS response of URCS to these VHF, against the needs of beneficiaries and communities focused on the areas of most ‘added value’ of the URCS; community engagement mobilisation and support, documenting any unintended outcomes and best practice r... more

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Women Cancer
recommended

Henke, A.; and S. Mauder The MEDBOX Team (2021) CC

MEDBOX Issue Brief No.17, 21 November 2021 Women's cancers have a significant impact on women's health worldwide. According to the World Health Organisation, nearly three million women are diagnosed with breast or cervical cancer every year. In this Issue Brief you will find more information.

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Report of the Task Force on Conservation & Sustainable use of Medicinal Plants

Government of India, Planning Commission (2000) C1

Medicinal plants occupied an important position in the socio-cultural, spiritual and medicinal arena of rural people of India. T The present report is based on contribution made by members of the task force and many other experts on medicinal plants. We hope the report on implementation will promot... more

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Practice Parameter on Disaster Preparedness

Pfefferbaum, B., Shaw, J.A. & American Academy of Child and Adolescent Psychiatry (AACAP) Committee on Quality Issues (CQI) American Academy of Child and Adolescent Psychiatry (AACAP) (2013) CC

AACAP OFFICIAL ACTION | This Practice Parameter identifies best approaches to the assessment and management of children and adolescents across all phases of a disaster. Delivered within a disaster system of care, many interventions are appropriate for implementation in the weeks and months after a d... more

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Responses of the Catholic Church to HIV and AIDS in Africa: Lessons learned

Fleischer, K., et al. German Bishops' Conference Research Group on International Church Affairs (2015) CC

An international field study by African and German theologicans and health workers.

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Malawi National Communication and Advocacy Strategy for Pre-Exposure Prophylaxis (PrEP)

United States Agency for International Development; President's Emergency Plan for AIDS Relief; National AIDS Commission MAlawi (2022) CC

Evidence shows that oral pre-exposure prophylaxis (PrEP) reduces the risk of contracting HIV during sexual intercourse by more than 90% when taken daily. It is for this reason the National HIV Prevention Strategy 2015-2020 (2018 Revision) emphasises the role of preexposure prophylaxis (PrEP) in ... more

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National List of Essential Medicines for Adults. NEML, 6th edition, 2015 - Rwanda

Ministere de la Sante, Rwanda (2010) C_WHO

The 6th edition of the essential medicine list has been developed based on the 5th edition list of essential medicines, the National Standard Treatment Guidelines and Protocols 2013, list of laboratory commodities and List of Consumables used in public health facilities.

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World Heart Federation Roadmap for Heart Failure

Ferreira, J.P.; Kraus, S.; Mitchell, S. et al. Global Heart (2019) CC

In 2012, all Member States of the World Health Organization (WHO) endorsed a historical target to reduce premature mortality from noncommunicable diseases (NCD). This commitment was echoed in 2015 by the United Nations Sustainable Development Goals, which included a target to reduce premature morta... more

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Children in disasters - games and guidelines to engage youth in risk reduction

International Federation of Red Cross and Red Crescent Societies (IFRC), South East Asia Regional Office (2010) C1

This guideline consists of two main parts:
i.) Guidelines for Red Cross and Red Crescent national societies on how to start up and engage with other stakeholders in country in rolling out disaster risk reduction (DRR) education and awareness activities for children - not only in school, but also... more

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Libya: National Action Plan on Prevention and Containment of Antimicrobial Resistance

State of Libya (2019) C_WHO

The Libyan national action plan has been aligned with WHO five objectives. Analysis of the current situation and addressing the gaps and the needs to reach the main goal “one health” approach involves several national sectors and actors, including human and veterinary health, agriculture and foo... more

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CONSENSUS DOCUMENT FOR MANAGEMENT OF SOFT TISSUE SARCOMA AND OSTEOSARCOMA

Indian Council of Medical Research (ICMR) (2016) C1

Prepared as an outcome of ICMR Subcommittee on Soft Tissue Sarcoma and Osteosarcoma | This consensus document on Management of Soft Tissue Sarcoma and Osteosarcoma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular ... more

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UNICEF South Sudan Mid-Year Humanitarian Situation Report January-June 2018

United Nations Children’s Fund (UNICEF) (2018)

- Twenty-two joint integrated rapid response mechanism (IRRM) missions were conducted in 11 counties and reached 305,887 people including 65,432 children under 5 years of age.
- UNICEF’s Integrated Community Mobilization Network reached 345,219 households (total population 2.1 million) advoca... more

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Reducing Antimicrobial Resistance and Hospital-Associated Infections: The Role of the Hospitalist

Dressler D. D., MD, MSc Director OF Society of Hospital Medicine (2005) CC

While infections that develop during hospitalization may appear to be an uncommon but recognized risk of hospital care today, the incidence of these infections has been increasing dramatically during the last 2 to 3 decades, and the risk of acquiring an organism that is resistant to 1 or more antibi... more

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Recommendations for cholera regional & global reporting

Global Task Force on Cholera Control (2025) CC

Regional and global cholera surveillance is the continuous compilation of data from affected countries, analysis and interpretation at the regional and global levels, and prompt dissemination of findings for public health action.

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Free to be me

United Nations Children's Fund (UNICEF) (2013)

A comic book guide for young people on how to live happily and healthily with HIV in their lives. In this booklet, young people share their stories about living with HIV and staying healthy in Namibia today. You will find out everything you need to know about living happily and healthily with HIV. I... more

Women Cancer recommended

Women Cancer
recommended