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Malaria Vaccines: Progress to Date

Stanisic, D. I.; and M.F. Good (2023) CC2

BioDrugs. 2023 Sep 20;37(6):737–756. doi: 10.1007/s40259-023-00623-4 There are many malaria vaccine candidates in development, with more than a dozen of these in clinical development. RTS,S/AS01 (also known as Mosquirix) is the most advanced malaria vaccine and was shown to have modest efficacy ... more

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Declaration for accelerated malaria mortality reduction in Africa: commitment that “No one shall die from malaria”

Ministers of Health of High Burden High Impact (HBHI) Countries in Africa (2024) CC

Issued by the Ministers of Health of High Burden High Impact (HBHI) countries in Africa. Yaounde Declaration. Ministers committed to strengthening their health systems, stepping up domestic resources, enhancing multisectoral action and ensuring a robust accountability mechanism,” notes Dr Daniel ... more

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MEDBOX NCD Video

MEDBOX (2025) CC

Noncommunicable diseases (NCDs) are chronic medical conditions that are not spread from person to person. Unlike infectious diseases, which are caused by bacteria, viruses, or other pathogens, NCDs are typically long-lasting and result from a combination of genetic, physiological, environmental, and... more

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Issue Brief: Update on TB 2025

The MEDBOX Team (2025) CC

Tuberculosis (TB) remains a significant global health challenge, with an estimated annual death rate of approximately one per 100,000 people in countries with low TB prevalence. Rapid reductions in TB cases and deaths worldwide depend on research breakthroughs, including the development of new vac... more

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Mpox Surveillance Reporting Protocol for African Union Member States

Africa Center for Disease Control and Prevention CDC (2024) CC

On 13 August 2024, the Africa Centres for Disease Control (Africa CDC) declared the multi-country mpox outbreak a public health emergency of continental security, with strong recommendations to improve surveillance and vaccine deployment in all AU Member States. On 14 August 2024, the WHO Director-G... more

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Surveillance Mpox. Protocole de notification pour les états membres de l'union Africaine
recommended

Africa Center for Disease Control and Prevention CDC (2024) CC

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The Supply Chain Manager's Handbook: A Practical Guide to the Management of Health Commodities
recommended

John Snow, Inc. (JSI) (2020) CC

The handbook is the starting point for anyone interested in learning about and understanding the key principles and concepts of supply chain management for health commodities. Concepts described in this handbook will help those responsible for improving, revising, designing, and operating all or par... more

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Clinical Profile and Management of Patient Patients with Ischemic Heart Disease and/or Peripheral Artery Disease in Clinical Practice: The APALUSA Study

Barrios, V.; Escobar, C.; Suarez C. et al. Journal of Clinical Medicine (2022) CC

This study was aimed to ascertain the clinical profile and management of patients with ischemic heart disease (IHD) and/or peripheral artery disease (PAD). In this observational and cross-sectional study developed in 80 hospitals throughout Spain, consecutive adults with stable IHD and/or PAD were i... more

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Ukraine: Civilian casualties as of 24:00 30 October 2022

UN Office of the High Commissioner for Human Rights (OHCHR) (2022) C2

ate: 31 October 2022 From 24 February 2022, when the Russian Federation’s armed attack against Ukraine started, to 30 October 2022, the Office of the UN High Commissioner for Human Rights (OHCHR) recorded 16,295 civilian casualties in the country: 6,430 killed and 9,865 injured. This included: -... more

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Ukraine: Civilian casualties as of 24:00 30 October 2022. Україна: втрати серед цивільних осіб

Office for the Coordination of Humanitarian Affairs OCHA (2022) C2

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The Lancet Commission on the future of care and clinical research in autism

The Lancet Commission (2021) CC

Awareness of autism has grown monumentally over the past 20 years. Yet, this increased awareness has not been accompanied by improvements in services to support autistic individuals and their families. Many fundamental questions remain about the care of people with autism—including which intervent... more

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Diet

Institute for Health Metrics and Evaluation (IHME) Institute for Health Metrics and Evaluation (IHME) (2024) CC

The webpage from the Institute for Health Metrics and Evaluation (IHME) discusses the global impact of diet on health, highlighting poor dietary habits as a major contributor to deaths worldwide, primarily through cardiovascular diseases. It emphasizes the health risks of high sodium intake and insu... more

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Life after Death

Cobb, L. NPR (2015) CC

It’s a big number, and yet it still fails to show the total damage of the Ebola epidemic – not just the deaths, but the loss of trust, traditions and fragile health systems. NPR has a lovely multimedia piece on one Liberian community traumatized by Ebola that does show that toll. What is strikin... more

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TB Treatment for Children – Drugs, dosages & FDCs

TBFacts.org (2017) C2

TB treatment for children is fundamentally the same as for adults, with a combination of TB drugs needing to be taken for a number of months. TB treatment for children consists of an intensive phase followed by a continuation phase. The purpose of the intensive phase is to rapidly eliminate the majo... more

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Peru Country Strategic Plan (2018–2022)

World Food Programme (2017) CC

This country strategic plan is based on consultations with the Government and other partners. It proposes a significant strategic shift to enable WFP to meet the Government’s expectations, considering the recommendations of the strategic review. The country office has strengthened its approach to ... more

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Current Profile of New HIV Infections Among Adults in Northern Benin in 2016

Cossi Angelo Attinsounon, Comlan Albert Dovonou, René Kèkè, Cossi Adébayo Alassani, Kouessi Anthelme Agbodandé, Finagnon Armand Wanvoegbe, Angèle Kouanou-Azon, Djimon Marcel Zannou Science Publishing Group (2017) C2

Objective: The study aimed to describe the current epidemiological, clinical and immunological profile of newly detected HIV - positive patients in Northern Benin by 2016. Methods: It was a prospective study conducted from May 2 to October 31, 2016 on three main sites of care of people living with... more

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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In Control: A Practical Handbook for Professionals Working in Health Emergencies Internationally RKI

Robert Koch Institut RKI (2023) CC

The greatest risk to persons engaging in international medical emergency response is poor preparation. The In Control handbook hopes to provide a remedy. At the time of writing, we are living through the Coronavirus (COVID-19) pandemic, a health emergency that disregards physical borders, brin...gs into focus social inequalities and affects people on every continent. This shared challenge requires unprecedented measures and the collaboration of the brightest minds to support global health protection through this crisis and beyond. Healthcare infrastructures have to be strengthened, public health capacities and processes upgraded, medical countermeasures and vaccinations found and psychosocial side-effects treated. Solidarity is the normative order of the day and the human species has to collaborate to face this invisible threat. Hiding and living in fear is not an option in this interconnected world. We have both a responsibility and an opportunity to make substantial contributions to a safer, healthier and more sustainable future for us all. The existence of this handbook is an impressive example of solidarity. Over 50 authors from more than 15 institutes and organisations have come together voluntarily within a very short time to make their expertise available and enable cross-sectoral thinking. Knowledge is bundled, resources are combined, information gaps are filled. The In Control handbook is not a theoretical treatise of possible dangers, but a collection of subject-matter expertise, written by experts and practitioners who have shaped health topics over the past 20 years in the most diverse corners of the world. The Centre for International Health Protection at the Robert Koch Institute (RKI) is collaborating with its partners and investing heavily in the build-up of operational know-how and capacity to support health crisis response abroad. This is done by preparing and enabling professionals to deploy safely across the world to assist those in need. In Control addresses the multi-faceted challenges of an international deployment. Readers will find not only technical medical information, but also insights into, for example, the fragility of our environment, the cultural differences that influence risk communication or the dilemmas arising from social distancing. Legal principles are highlighted, along with ethical guidance to ensure that our actions and decisions correspond to the highest moral standards. more

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A case study of the role of an Essential Health Benefit in the delivery of integrated health services in Zambia

Luwabelwa, M.; Banda, P; Palale M.; Chama-Chiliba, C. Regional Network for Equity in Health in east and southern Africa (EQUINET) (2017) C1

Regional Network for Equity in Health in east and southern Africa (EQUINET): Disussion Paper 111
The health services delivery system in Zambia is pyramid in structure, with primary healthcare (PHC) services at community level, at the base, followed by first and second level hospitals at distric... more

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Mental Health and Psychosocial Support for Staff, Volunteers and Communities in an Outbreak of Novel Coronavirus

Psychosocial Centre International Federation of Red Cross and Red Crescent Societies (2020) C1

Introduction The novel Coronavirus (nCoV) epidemic in 2019 -2020 has recently emerged. The route of transmission is not totally known, although it is known that it can spread from person to person, and local health care systems may be ill-equipped to handle a large-scale outbreak. Furthermore, misco... more

Surveillance Mpox. Protocole de notification pour les états membres de l'union Africaine recommended

The Supply Chain Manager's Handbook: A Practical Guide to the Management of Health Commodities recommended

Surveillance Mpox. Protocole de notification pour les états membres de l'union Africaine
recommended

The Supply Chain Manager's Handbook: A Practical Guide to the Management of Health Commodities
recommended