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Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe disease in humans caused by Marburg marburgvirus (MARV). Although MVD is uncommon, MARV has the potential to cause epidemics with significant case fatality rates.
Marburg and Ebola are filoviruses that cause hemorrhage, multiple organ failure, and high mortality rates. Diagnosis is with enzyme-linked immunosorbent assay, polymerase chain reaction (PCR), or electron microscopy. Treatment is supportive. Strict isolation and quarantine measures are necessary to
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contain outbreaks.
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Fact Sheet
Training: Infection Prevention and Control for Marburg Virus Disease in Non-U.S. Healthcare Settings
These training materials apply to all healthcare facilities that are not designated MVD treatment facilities.
All health and care workers require the knowledge and skills to prevent the transmission of Ebola virus or Marburg virus when providing care for patients. This course provides an overview of the mode of transmission of these viruses, the personal protective equipment required by health and care work
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ers and measures to take for rapid identification and isolation as well as managing the environment.
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On 14 August 2024, the Director-General of the World Health Organization determined that the upsurge of mpox in a growing number of countries in Africa constitutes a new public health emergency of international concern (PHEIC) under the International Health Regulations (IHR) (2005)
The Global Action Plan on Antimicrobial Resistance (AMR) calls for making AMR a core component of professional education and training. In 2018, the World Health Organization (WHO) published Competency framework for health workers’ education and training on AMR to ensure that academic institutions
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and regulatory agencies provided pre-service and in-service training to equip health workers with the adequate competencies to address AMR. This was followed by Health workers’ training and education on AMR: curricula guide, which outlines the learning objectives and expected outcomes of pre-service training of health workers to improve curricula. These tools were designed to strengthen the capacity of health workers in various settings to address the growing challenge of AMR.
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Please find here the latest Update on MVD in Rwanda
Issue Brief Marburg virus disease (MVD)
recommended
Issue Brief No. 40 provides healthcare professionals with the most relevant treatment guidelines, prevention measures and training material on MVD
interim guidance, 25 November 2024
Ces recommandations temporaires sont émises à l’intention des États Parties qui font face à une transmission du virus de la mpox (MPXV), y compris, sans que cette liste soit exhaustive, ceux touchés par une transmission communautaire persistante et ceux où l’on observe des groupes de cas o
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u des cas sporadiques d’infection par le clade Ib du MPXV liés à des voyages.
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Cette banque de questions est un menu de questions qualitatives relatives aux connaissances, aux perceptions et aux pratiques du personnel de santé lors d'épidémies de maladies infectieuses. La banque de questions générera des données qualitatives sur la compréhension subjective qu'ont les pr
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ofessionnels de la santé des risques, de la gestion des cas, de la protection et des opérations plus larges en cas d'épidémie. Ces données peuvent être utilisées pour informer les activités de communication sur les risques et d'engagement communautaire, ainsi que d'autres piliers de la réponse. Certains des sujets abordés dans ces questions sont complexes, par exemple la stigmatisation ou les opinions sur la sécurité des vaccins.
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During the reporting period, significant progress was made in strengthening the mpox response across the continent. The lessons learned and challenges identified during the joint mpox continental intra-action review (IAR), which took place successfully in December 2024 in Addis Ababa have guided the
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development of the action plan for the response to the mpox epidemic in January and February 2025.
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In conclusion, the current evidence does not support the use of mpox antigen RDTs in the field. More data are expected from independent evaluations conducted by Africa CDC, FIND or other organizations
Diagnostic de mpox.
The WHO’s Early Warning, Alert and Response System (EWARS) is a tool used in emergencies such as conflicts or natural disasters to quickly detect and respond to disease outbreaks. It helps set up simple and reliable surveillance systems even in places without stable electricity or internet, using
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kits that include phones, laptops, and solar chargers. EWARS supports national health authorities during crises and can later be integrated into the regular health surveillance system.
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The document outlines comprehensive guidelines for managing cholera outbreaks in South Africa, focusing on prevention, diagnosis, treatment, and public health measures. It emphasizes the importance of rehydration therapy, sanitation, clean water access, and community involvement to control the sprea
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d of the disease. It also provides protocols for handling outbreaks, including case identification, laboratory confirmation, and multi-sectoral coordination to reduce morbidity and mortality rates.
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Managing epidemics
recommended
Key facts about major deadly diseases.This manual provides concise and up-to-date knowledge on 15 infectious diseases that have the potential to become international threats, and tips on how to respond to each of them.
You can download an interactive version directly at the website
http://www.who.
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int/emergencies/diseases/managing-epidemics/en/
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This guidance has been developed in line with the WHO corporate risk management framework, the WHO business continuity and contingency plans, as well as the Inter-Agency Emergency Response Preparedness Framework. It is based on a common organiza-tional approach and procedures for managing including
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emergency response across all hazards and at each level of the Organization. It relates WHO’s responsibilities (1) under the International Health Regulations (2005) and the Sendai Framework for Disaster Risk Reduction 2015-2030, and other international treaties; (2) as the United Nations’ lead agency for health and the health cluster; and (3) as a member of the United Nations or Humanitarian Country Teams
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