This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is
a key component of leprosy treatment, as it is vital to prevent the progression of the infection.
Treatment with rifampin and other antibiotics is highly effective and cures 98% of patients with
the ...leprosy infection. Furthermore, the relapse rate is very low, at about 1% over 5–10 years.
There is little M. leprae drug resistance in leprosy and few reports of multi-drug resistance (1, 2, 3,
4, 5, 6, 7, 8). An antibiotic treatment may take months or years to produce clinical improvement,
especially in patients with an initial high bacterial index (BI).
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Current Issüs Arising from Tuberculosis Screening with Interferon-Gamma- Release Assays (IGRAs)
Pneumologie 2015; 69: 271–275
Learning from earthquake relief and recovery operations
Fornecer diretrizes de cuidados para profissionais da saúde expostos ao novo coronavírus (COVID-19) em estabelecimentos de saúde, e conduta na exposição ocupacional ao vírus. • Esta ferramenta irá ajudar a determinar o risco de infecção dos profissionais da saúde que foram expostos a um ...paciente com COVID-19 e orientar as decisões sobre as ações apropriadas. Além disso, oferece recomendações para a conduta adequada com esses profissionais da saúde, de acordo com o risco de infecção. Estas recomendações são preliminares e sujeitas à revisão, à medida que novas evidências estiverem disponíveis.
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A Guide For Multicentre Trials in High-Burden Countries
Der Artikel "Händedesinfektion unter den Bedingungen der SARS-CoV-2-Pandemie" war am 4.5.2020 online vorab erschienen und ist nun in der regulären Ausgabe des Epidemiologischen Bulletins 19/2020 zu finden.
This briefing paper provides an overview of pre-exposure prophylaxis (PrEP) for people planning, commissioning or providing HIV prevention activities in the UK. It does this by reviewing thirty key questions about PrEP and how it might be implemented in the UK.
Mund-Nasen-Bedeckung im öffentlichen Raum als weitere Komponente zur Reduktion der Übertragungen von COVID-19. Strategieergänzungen zu empfohlenen Schutzmaßnahmen und Zielen (3. Update) Das RKI empfiehlt ein generelles Tragen einer Mund-Nasen-Bedeckung (MNB) in bestimmten Situationen im öffentl...ichen Raum als einen weiteren Baustein, um Risikogruppen zu schützen und den Infektionsdruck und damit die Ausbreitungsgeschwindigkeit von COVID-19 in der Bevölkerung zu reduzieren. Diese Empfehlung beruht auf einer Neubewertung aufgrund der zunehmenden Evidenz, dass ein hoher Anteil von Übertragungen unbemerkt erfolgt, und zwar bereits vor dem Auftreten von Krankheitssymptomen. Ziel des im Epidemiologischen Bulletin 19/2020 veröffentlichten Artikels ist es, eine kurze Übersicht zum fachlichen Hintergrund der Empfehlung zu geben und zu erläutern, welche Dinge hierbei zu berücksichtigen sind.
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In 2022, a total of 6,131 confirmed malaria cases were reported across the EU/EEA. Of these, 5,375 had a known importation status and nearly all (99.8%) were travel-related. Only 13 infections were acquired within Europe, with seven occurring in France, three in Germany, two in Spain and one in Irel...and. A distinct seasonal peak was observed from July to September, reflecting travel to malaria-endemic regions. Notification rates were higher among men than women, with a male-to-female ratio of 2:1. France reported the highest number of cases, followed by Germany, Spain, Italy and Belgium. After dropping sharply in 2020 due to travel restrictions imposed during the pandemic, overall notification rates increased again in 2021 and 2022, reaching 0.8 cases per 100,000 people. These findings emphasise that malaria in Europe is predominantly an imported disease closely linked to international travel, with sporadic local transmission being rare.
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Disability at a Glance 2015 focuses on barriers to the employment of persons with disabilities in the Asia-Pacific region, and offers solutions to strengthen their employment prospects. Employment is not only the primary means of livelihood generation; it also provides individuals with the purpose a...nd meaning of playing a productive role in society. Equal access to employment is therefore vital, and barriers to work faced by persons with disabilities must be removed.
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Atherosclerotic lower-extremity peripheral artery disease (PAD) is increasingly recognized as an important cause of cardiovascular morbidity and mortality that affects more than 230 million people worldwide. Traditional cardiovascular risk factors, including advanced age, smoking, and diabetes, are ...strongly linked to an increase risk of PAD. Although PAD has been historically underappreciated compared to coronary artery disease and stroke, greater attention on PAD in recent years has led to important new epidemiologic insights in the areas of thrombosis, inflammation, dyslipidemia, and microvascular disease. In addition, the concept of polyvascular disease, or clinically-evident atherosclerosis in multiple arterial beds, is increasingly identified as a particularly malignant cardiovascular disease worthy of special clinical attention and further study. It is noteworthy that PAD may increase the risk of adverse outcomes in similar or even greater magnitude than coronary disease or stroke. In this review, we highlight important new advances in the epidemiology of PAD with a particular focus on polyvascular disease, emerging biomarkers, and differential risk pathways for PAD compared to other atherosclerotic diseases.
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A discussion paper on the scope of the problem, its drivers, and strategies for moving forward for policy, practice, and research
In many protracted emergencies, the prevalence rates of global acute malnutrition (GAM) regularly exceed the emergency threshold of > 15% of children with acute malnutri...tion (< -2 weight-for-height z-scores (WHZ) or with nutritional edema), despite ongoing humanitarian interventions. The widespread scale and long-lasting nature of “persistent GAM” means that it is a policy and programming priority.
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The present report is submitted pursuant to Security Council resolution 2164 (2014), by which the Council extended the mandate of the United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA) and requested me to report to it every three months on the implementation of the re...solution and the progress on the implementation of the Mission’s mandate. The present report covers the period from 17 December 2014 to 19 March 2015.
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Education of children with disabilities in India and Pakistan: An analysis of developments since 2000 | Background paper prepared for the Education for All Global Monitoring Report 2015 | Education for All 2000-2015: achievements and challenges