The technical note from the Global Task Force on Cholera Control (GTFCC) examines the risks and benefits of vaccinating pregnant women with WHO-prequalified oral cholera vaccines (OCVs) during mass vaccination campaigns. It highlights that three WHO-approved vaccines (Dukoral®, Shanchol™, and Euv...ichol®) offer sustained protection and a strong safety profile.
While these vaccines are not explicitly contraindicated for pregnant women, there is limited clinical data on their use during pregnancy. However, studies indicate that pregnant women with cholera face higher risks of fetal loss, stillbirth, and complications, especially if they experience severe dehydration. Some evidence suggests that vaccination can reduce cholera incidence in pregnant women and indirectly protect infants.
Although no controlled trials have focused on pregnant women, retrospective studies in Guinea and Zanzibar showed no significant increase in adverse pregnancy outcomes after OCV administration. The GTFCC concludes that the benefits of vaccination outweigh the risks, particularly in high-risk areas, and recommends including pregnant women in cholera vaccination campaigns while continuing to monitor safety data.
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Through technical consultations with countries and partners, WHO has led the development of Preparedness and Resilience for Emerging Threats Module 1: Planning for respiratory pathogen pandemics. Version 1.0. The Module, currently available as an advanced draft, builds on previous pandemic lessons a...nd guidance, and has the following new elements:
It presents an integrated and efficient respiratory pathogen pandemic planning approach covering both novel pathogens and those known to have pandemic potential;
It enables coherence in addressing pathogen-agnostic and pathogen-specific elements for better preparedness;
It gives an organizing framework including operational stages and triggers for escalation and de-escalation between pandemic preparedness and response periods;
It contextualizes 12 IHR (2005) core capacities within the five components of health emergency preparedness, response and resilience (HEPR), from the respiratory threats perspective; and
It describes the critical sectors for respiratory pathogen pandemic preparedness to trigger multisectoral collaboration.
WHO will finalize and publish this Module after a global technical meeting that will be held on 24-26 April 2023.
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Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
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Lancet Glob Health 2023; 11: e1805–18
WEEKLY EPIDEMIOLOGICAL RECORD, NO 23, 7 JUNE 2024, pp.307-318
The most recent estimate of the global number of deaths from dog-mediatedrabies is 59 000 per year.1 Rabies is associated with a 99.9% fatality rate and severe trauma in families in which a rabies death
occurs, and remains a major publ...ic health concern in most of Africa and Asia and some parts of South America
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The article "Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review" analyzes factors contributing to poor asthma control in African youth. Based on studies conducted between 2014 and 2019 in Nigeria, Uganda, and South Africa, the review identifies key... challenges such as limited access to asthma diagnosis, inadequate use of inhaled corticosteroids, and environmental and socio-economic factors. It finds that urban living, older age, and concurrent allergic conditions significantly affect asthma management. The study emphasizes the need for improved diagnostic tools, better access to treatment, and tailored public health interventions to enhance asthma outcomes in African children.
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The document focuses on providing access to clean water and educating people about cholera, including its causes, symptoms, and prevention. It discusses the impact of cholera outbreaks, particularly in the Middle East, and highlights the importance of sanitation, hygiene, and proper water treatment ...to prevent the spread of the disease. The text also emphasizes the need for public awareness campaigns and emergency response efforts to mitigate cholera’s effects on vulnerable communities.
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По данным ВОЗ профилактика и борьба с инфекциями (ПКИЗ) –это научный подход и практическое решение, призванное предотвратить вред, который может быть причин...н инфекцией пациентам и медицинским работникам. Он основывается на исследовании инфекционных заболеваний, эпидемиологии, социологии и укреплении системы здравоохранения. ПКИЗзанимает уникальное положение в области обеспечения безопасности пациентов и общего охвата качественными услугами по охране здоровья, поскольку касается медицинских работников и пациентов при каждом контакте с системой здравоохранения.
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Заданими ВООЗ профілактика та контрольз інфекційними захворюваннями(ПКІЗ) –це науковий підхід та практичне рішення, покликане запобігти шкоді, яка може бути ...заподіянаінфекцією пацієнтамта медичнимпрацівникам. Вінґрунтується надослідженніінфекційних захворювань, епідеміології, соціологіїта зміцненні системи охорони здоров’я. ПКІЗзаймає унікальне положенняв галузі забезпечення безпеки пацієнтів та загальногоохоплення якісними послугами з охорони здоров’я, оскільки стосується медичних працівників та пацієнтів прикожному контакті з системою охорониздоров’я.
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Временные рекомендации8 января 2021 г
24 ФЕВРАЛЯ 2020
г. // ПРЕДВАРИТЕЛЬНАЯ РЕДАКЦИЯ
В системе здравоохранения больницы играют важнейшую роль в обеспечении населения основной медицинской помощью, особе...нно в кризисных ситуациях. Продолжительные и сочетанные вспышки могут приводить к прогрессирующему распространению заболеваний и быстрому увеличению потребностей в медицинском обслуживании, спрос на которое может превысить возможности и отдельных больниц, и системы здравоохранения в целом.
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Mission report: June 11-20, 2017