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Publication Years
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Integrated Outbreak Analytics (IOA) applies a multidisciplinary approach to understanding outbreak dynamics and to inform outbreak response. It aims to drive comprehensive, accountable, and effective public health and clinical strategies by enabling communities, and national and subnational health a
...
uthorities to use data for operational decision-making. IOA embraces a holistic perspective of outbreak dynamics throughout: from the trigger questions to the data that are collected or accessed, to the interpretation of results and the recommendations that follow. In addition, IOA promotes co-development and monitoring of evidence informed actions.
The IOA toolkit aims to provide a clear understanding of IOA and highlight the importance of using an integrated, holistic approach to manage outbreak responses. It provides step-by-step guidance for setting up IOA and putting IOA principles into action. Finally, this toolkit provides guidance on applying IOA in humanitarian and emergency contexts, offering a practical and adaptable approach to informing public health emergency responses.
Developed based on the model from the Democratic Republic of the Congo (DRC), its creation involved extensive consultation with experts experienced in IOA applications. The toolkit was piloted in Tanganyika Province, DRC, as well as Somalia and Sudan, demonstrating its adaptability to diverse emergency scenarios. It builds upon an existing array of tools, templates, reports, case studies, animations, and publications used by stakeholders in diverse contexts.
more
The emergence of SARS-CoV-2 has significantly altered the epidemiology of other infectious diseases, making investigations into its co-infection with malaria particularly relevant in endemic regions. This review examines the epidemiological, incubat
...
ion and clinical features of the two diseases, highlighting the diagnostic challenges and strategies for accurate detection. Emerging immunological and genetic evidence indicates that prior exposure to malaria may reduce the severity of outcomes of SARS-CoV-2 infection through mechanisms involving ACE2 downregulation, TLR signalling, T-cell activation and upregulation of coinhibitory receptors. Additionally, potential control measures are discussed, including vaccine development, the repurposing of antimalarial drugs, the exploration of natural products, innovations in bioinsecticides, and the strengthening of electronic disease surveillance. These insights provide valuable guidance for clinical management and public health policy, while emphasising the need for continued research into the complex interactions between SARS-CoV-2 and malaria.
more
The Centrum für Reisemedizin (CRM) is a comprehensive source of information, guidelines and resources on travel medicine for healthcare professionals and travellers. Its website offers up-to-date recommendations on disease prevention, vaccinations,
...
malaria prophylaxis and health risks in different regions around the world. As part of the Thieme Group, the CRM promotes evidence-based medical counselling, training and educational materials for patients, with the aim of improving travel health outcomes and ensuring safe international mobility.
Accessed on 26/08/2025.
more
This infographic from the Tropeninstitut illustrates the malaria transmission cycle. It begins when an Anopheles mosquito bites a human and injects its sporozoites into the bloodstream. The sporozoites then travel to the liver where they mature and
...
release merozoites back into the bloodstream. The merozoites then infect red blood cells, resulting in the clinical symptoms of malaria. Some merozoites develop into gametocytes, which can be ingested by another mosquito when it bites the infected person again, thus continuing the transmission cycle.
The infographic serves as an educational tool, helping to explain the complex life cycle of the malaria parasite and the role of mosquitoes in spreading the disease.
Accessed on 26/08/2025.
more
To mark the International Day of the African Child, Medicines for Malaria Venture (MMV) celebrated the inclusion of three of its antimalarial medicines on the WHO Model List of Essential Medicines (EML) and the EML for Children (EMLc). These are two
...
artemisinin-based combination therapies (ACTs) for adults, children and infants, and a rectal artesunate formulation for the pre-referral treatment of severe malaria in young children. The approved therapies — pyronaridine–artesunate, dihydroartemisinin–piperaquine and rectal artesunate — offer child-friendly formulations and are the first-line treatment for uncomplicated malaria caused by Plasmodium falciparum and P. vivax. Inclusion in the EMLc facilitates national adoption, improves access to high-quality treatments and addresses the disproportionate malaria burden among children under five. This supports global efforts to reduce malaria mortality and advance elimination.
more
This document outlines the plan for a continental cholera prevention and control with the implementation framework for the Cholera IMST, detailing its governance structure, strategic priorities, and operational modalities
This Climate terminology bank provides key definitions and facts related to climate and resilience for Uganda’s refugee response. Its goal is to build a common understanding among stakeholders and support the integration of climate-smart practices
...
in humanitarian efforts.
more
The document provides a standardized protocol for evaluating the Early Warning Alert and Response Network (EWARN), a surveillance system used during humanitarian emergencies when regular national health surveillance may be disrupted. The purpose of EWARN is to detect outbreaks of communicable diseas
...
es early and enable rapid public health response. The guidance explains how the system should be assessed in terms of its structure, implementation, effectiveness, and usefulness. It outlines the key steps of evaluation: preparation, system description, data collection, and post-evaluation reporting. The protocol highlights common challenges observed in previous EWARN implementations, such as delays in establishing the system, limited data quality, weak outbreak response, and lack of clear transition plans back to routine surveillance systems. It emphasizes the need to evaluate both weekly disease reporting and alert verification processes, and to review attributes such as simplicity, data quality, timeliness, sensitivity, and stability. The document also provides templates for interviews, data review forms, and laboratory assessment, as well as guidance on conducting remote evaluations when access is limited. The overall goal of the protocol is to ensure that EWARN functions effectively to detect and respond to outbreaks and that practical recommendations are developed to improve the system’s performance and sustainability in emergency settings.
more
a landscape report of voluntary medical male circumcision priority countries.
This report provides the findings from the baseline implementation of these tools in 15 VMMC priority countries in 2021. It is intended for VMMC national programme leaders and implementing and global partners.
...
Its goals are to describe the baseline status of national VMMC programmes with respect to sustainability, identify programme strengths and weaknesses, and lay out a preliminary vision of the path towards sustainability
more
Epidemic Intelligence from Open Sources (EIOS) is the world’s leading initiative for open-source intelligence for public health decision-making. It is led by the WHO as part of its constitutional mandate as the directing and coordinating autho
...
rity on international health work. EIOS is built on three pillars: a growing global community of practice, a range of multi-disciplinary collaborators and an evolving fit-for-purpose system. The system builds on a long-standing collaboration between WHO and the Joint Research Centre (JRC) of the European Commission (EC).
more
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health
Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for
HIV EID and VL POC diagn
...
ostic technologies in 2018 and awarded two manufacturers long-term arrangements
(LTAs) to supply WHO prequalified product
more
This user friendly and succinct course, provides learners with the opportunity to have a basic understanding of HIV and its treatment. It is useful as an introductory course for those who are caring for people living with HIV or anyone who is inter
...
ested to acquire knowledge in this field.
more
The text “Pathogen Genomic Surveillance Policy Framework (2023)” is a strategic framework developed by Africa CDC to strengthen genomic surveillance of pathogens in the Member States of the African Union.
Its content focuses on how African coun
...
tries can systematically integrate genome sequencing into their public health systems in order to detect infectious diseases more rapidly, monitor outbreaks more effectively, and support evidence-based public health decision-making.
The report was developed in the context of the COVID-19 pandemic, which demonstrated the importance of genomic surveillance for identifying virus variants and enabling effective crisis management. The aim of the framework is to sustainably expand the capacities built during the pandemic and to apply them to additional pathogens beyond COVID-19.
more
The document is a practical handbook developed by the European Centre for Disease Prevention and Control (ECDC) that provides guidance on how to design, plan, conduct, and evaluate simulation exercises in public health settings. Its main purpose is
...
to help organisations improve their preparedness and response to communicable disease outbreaks by using structured exercises as a training and evaluation tool. The handbook explains different types of exercises, outlines the steps involved in organising them, and highlights the importance of clear objectives, coordination, and evaluation. Overall, it aims to strengthen emergency preparedness by enabling organisations to identify weaknesses, improve collaboration, and enhance their ability to respond effectively to public health crises.
more
The book is designed for use everywhere, and especially in low-resource settings. With its focus on improving conditions at the community level, this book proposes ways to challenge stigma and build support for people with epilepsy, especially in pl
...
aces where care is limited. Prevent, manage, live well with epilepsy, and take action against epilepsy stigma with this friendly and illustrated guide. This comprehensive, easily understood resource gives you a handle on complex physical and social aspects of epilepsy.
Now available to purchase now through Hesperian’s online book store!
more
WeRobotics
WeRobotics
(2026)
WeRobotics aims to decentralise power and knowledge in the technology sector. Instead of sending external actors to crisis regions, the organisation builds up local expertise. Its ‘Flying Labs’ in Asia, Africa, Latin America and the Middle East
...
are autonomous partner organisations that use drones, data analysis and robotics to meet local needs – such as mapping floods, distributing medicines or monitoring ecosystems.
more
Emergency Medical Teams 2030 strategy
recommended
The Emergency Medical Teams (EMT) initiative plays a vital role in building this stronger and
more resilient global health emergency architecture, both by driving its formation and by
contributing to a rapidly deployable global health emergency co
...
rps. The Initiative and EMTs
bring something unique to health emergency preparedness and response – they bring
standards, professionalism, reliability, scalability, coordination, and the ability and willingness to
rapidly deploy wherever and whenever they are most needed. Most importantly, EMTs save lives.
more
The International Coordinating Group (ICG) on Vaccine Provision was established in 1997 as a mechanism to manage and coordinate the provision of emergency vaccine supplies and antibiotics to countries during major outbreaks.
This channel provides foundational understanding of the ICG and
...
its mechanism to access the emergency vaccine stockpile for Ebola, yellow fever, cholera and mening
more
The Camp Managment Toolkit
recommended
Applicable to both IDP and refugee scenarios, the Toolkit incorporates a wide range of relevant information on managing displaced populations living in communal settings (collective centres, spontaneous sites, established camps, etc.). Large scale displacements caused by recent conflict and natural
...
disaster events have created a high demand for the Toolkit, which has proven an invaluable resource for field practitioners, government actors and displaced populations since its original release in 2004.
Available in other languages
more
The IMCI model handbook provides a detailed explanation of the IMCI case management guidelines. It is organized into seven main parts: overview of the IMCI process; assess and classify the sick child age 2 months up to 5 years; assess and classify the sick young infant age 1 week up to 2 months; ide
...
ntify treatment; treat the sick child or the sick young infant; communicate and counsel; and give follow-up care.
Teaching institutions are advised to adapt the handbook in two ways:
to ensure that all text, charts and illustrations are consistent with nationally-adapted IMCI clinical guidelines, and
to ensure that its content and format corresponds to the teaching approach used by the institution.
more
