SIGN 143. A national clinical guideline
Published May 2015, Revised 2018
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In October 2022, President Biden signed the Global Malnutrition Prevention and Treatment Act (GMPTA) into law, which directs USAID to prevent and treat malnutrition globally. The GMPTA further codifies USAID’s leadership on nutrition, with a focus on evidence-based interventions across health syst...ems and food systems, in both development and humanitarian settings.
Realizing the potential of good nutrition to save lives and ensure a brighter future for generations to come is central to U.S. Government priorities. For over 60 years, USAID has been a leader in the fight to end global malnutrition. Nutrition affects every aspect of human development: from the ability to fight disease, to children’s performance in school, to a nation’s health and economic advancement. There is overwhelming evidence of the power of good nutrition but, due to challenges in accessing safe, nutritious foods and health and sanitation services, many people in low- and middle-income countries remain undernourished.
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Harm reduction: evidence, impacts and challenges
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Documentation des meilleures pratiques et des goulots d’étranglement à la mise en œuvre du programme au Sénégal .
Research Article
PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002374 August 8, 2017
In addition to the ongoing humanitarian emergencies in the country, the COVID-19 pandemic poses a potential monumental social and economic threat to Nigeria, with a devastating knock on effect for the most vulnerable population in the BAY states who have endured a decade of conflict. The UN system i...n Nigeria launched a One UN Response Plan to COVID-19 to support the rapid implementation of the Government’s National COVID-19 Multi-Sectoral Pandemic Response Plan and will continue to support strong coordination and coherence with all stakeholders responding to the pandemic.
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La pandémie causée par le coronavirus s’est propagée au Niger le 19 mars, date de la notification du premier cas. A la date du 21 juillet 2020, le pays avait enregistré 1 113 cas, dont 1 1018 guéris, 26 sous traitement et 69 décès. Selon l’analyse des données effectuée par le Ministère... de la santé publique, la pandémie a atteint un pic le 9 avril avec 69 cas enregistrés en une journée pour ensuite connaitre une courbe descendante. Cette tendance se maintient en dépit de la progression de la pandémie à Zinder, ainsi que dans les régions d’Agadez et de Diffa, qui étaient, jusqu’au 30 avril 2020, les seules régions épargnées par la COVID-19, et le fait que 169 agents de santé, soit 18,4% de cette catégorie de personnel, figurent parmi les cas confirmés.
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Hands-on information and practical advice for everyday life and work in the field as well as background information on crisis management structures in international organizations lie at the heart of the new handbook. It has been developed in the realm of Europe’s New Training Initiative for Civili...an Crisis Management (ENTRi) by the project coordination team at ZIF.
The handbook is designed to accompany civilian experts on their way to crisis management missions. In addition to providing a general overview of the institutional landscape of crisis management as well as relevant concepts, the handbook also provides practical information on a variety of issues that are common to working in a mission. From dealing with health and security challenges to technical information on radio operation, map reading, four-wheel driving – the ENTRi handbook is a valuable companion for work in a mission.
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orientations provisoires, première publication : 8 janvier 2021, mise à jour : 15 juin 2021, mise à jour : 19 novembre 2021, mise à jour : 21 janvier 2022
As our world changes, so too does the burden of disease. Globalisation, evolving trade and consumption patterns, and increased access to life-saving medical care are just some of the factors that have transformed the global health landscape.
A Global Analysis of Antimicrobial Resistance and Its Drivers.
Since the first State of the World’s Antibiotics report in 2015, antimicrobial resistance has leveled off in some high-income countries but continues to rise in many low- and middle-income countries (LMICs), where access to antibiotic...s has risen with increases in gross domestic product per capita. Per capita antibiotic consumption in LMICs is lower than in high-income countries, despite a higher infectious disease burden; however, consumption rates are rapidly converging. These trends reflect both better access to antibiotics for those who need them and increases in inappropriate antibiotic use.
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The new Global AIDS Strategy 2021--2026, End Inequalities, End AIDS, is a bold approach that uses an inequalities lens to close the gaps preventing progress to end AIDS
A global hunger crisis -- fuelled by conflict, economic turbulence and climate-related shocks -- has been exacerbated by the COVID-19 pandemic. The number of people experiencing food insecurity and hunger has risen since the onset of the pandemic. The IRC estimates that the economic downturn alone w...ill drive the number of hungry people up by an additional 35 million in 2021. Without drastic action, the economic downturn caused by COVID-19 will suspend global progress towards ending hunger by at least five years.
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This mapping of community experiences for the defense of the right to adequate housing in situations of risk of eviction or eviction in progress brings together practices and strategies used by families, collectives and community organizations that have different origins and interests in the region,... and also those on other continents.
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Background paper 9
The Independent Panel for Pandemic Preparedness and Response
May 2021
SBMFC Recommendations for PHC during the Pandemic of COVID-19 (edition 4)
This document answers questions and gives recommendations so that the Brazilian PHC can quickly receive the best possible scientific synthesis on the current situation of the pandemic of COVID-19
Glob Heart . 2020 Oct 13;15(1):69. doi: 10.5334/gh.891.
Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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