The guidelines are primarily intended for health-care professionals working in first- or second-level health-care facilities, including emergency, inpatient and outpatient services. They are also directed at policy-makers, health-care planners and programme managers, academic institutions, non-gover...nmental and civil society organizations to inform capacity-building, teaching and research agendas.
Web annex A provides the quantitative evidence reports, Web annex B summarizes the qualitative and economic evidence and Web annex C presents the Evidence-to-Decision frameworks.
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The objectives of this guideline are the same as those of the 2011 edition, namely to provide evidence-based normative guidance on interventions to improve adolescent morbidity and mortality by reducing the chances of early pregnancy and its resulting poor health outcomes. The specific objectives of... the guideline were to: 1. identify effective interventions to prevent early pregnancy by influencing factors such as early marriage, coerced sex, unsafe abortion, access to contraceptives and access to maternal health services by adolescents; and 2. provide an analytical framework for policy-makers and programme managers to use when selecting evidence-based interventions to prevent early pregnancy and negative health outcomes when they occur that are most appropriate for the needs of their countries and context. The recommendations and best practice statements described in this document aim to enable evidence-based decision-making with respect to preventing early pregnancy and poor reproductive outcomes among adolescents in low- and middle-income country contexts.
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Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P...lasmodium falciparum. Artemisinin-based combination therapy (ACT) has been recommended as first-line treatment for uncomplicated P. falciparum malaria in all populations, including pregnant women in their second and third trimesters, since 2006. However, for women in their first trimester of pregnancy, WHO recommended as first-line treatment a combination of quinine and clindamycin.
Based on a review of the evidence conducted in 2022, WHO now recommends artemether–lumefantrine, the ACT with the most human safety data available, as the preferred treatment for uncomplicated P. falciparum malaria in the first trimester of pregnancy. This document presents all relevant evidence on the effects and safety in early pregnancy of artemisinins and partner medicines used in ACTs from both studies in experimental animals and observational studies in humans.
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The document outlines essential steps and provides guidance to countries on the adoption and deployment of c-IPTp so that it is integrated into the existing health system. It draws upon best practices and lessons learned from pilot implementation experiences in eight African countries and targets st...akeholders at the national level that are involved in the provision of maternal and child services, including national and local policymakers and implementers of malaria, maternal health, child health, reproductive health and community health programmes, and nongovernmental and other organizations.
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The WHO guidelines for malaria bring together the Organization’s most up-to-date recommendations for malaria in one user-friendly and easy-to-navigate online platform.
The WHO guidelines for malaria bring together the Organization’s most up-to-date recommendations for malaria in one user-frie...ndly and easy-to-navigate online platform. The Guidelines supersedes 2 previous WHO publications: the Guidelines for the treatment of malaria, third edition and the Guidelines for malaria vector control. Recommendations on malaria will continue to be reviewed and, where appropriate, updated based on the latest available evidence. Any updated recommendations will always display the date of the most recent revision in the MAGICapp platform. With each update, a new PDF version of the consolidated guidelines will also be available for download on the WHO website.
This version of the Guidelines includes an updated recommendation for malaria vaccines, new recommendations on the use of near-patients qualitative and semiquantitative G6PD tests to guide anti-relapse treatment of P. vivax and P. ovale, updated recommendations on primaquine and the recommendation on the use of tafenoquine. It replaces the versions published on 16 February 2021, 13 July 2021, 18 February 2022, 31 March 2022, 3 June 2022, 25 November 2022, 14 March 2023 and 16 October 2023.
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Report of a virtual meeting 21–23 June 2022
Preferred product characteristics and clinical development considerations
Tropical Medicine and Health (2023) 51:29
Depuis 2010, la lutte contre le paludisme a permis de réaliser des progrès majeurs grâce à la distribution de moustiquaires, au diagnostic rapide, aux traitements à base d'artémisinine (ACT) et aux interventions préventives ciblées.
According to the WHO, there were an estimated 251 million malaria cases (95% of global cases) and 579,414 malaria deaths (97% of global deaths) in African Union Member States in 2023. 76% of these deaths were children under the age of five.
This policy brief presents a summary of current evidence on vulnerability to TB and proposes interventions for equitable, person-centred, and human rights-based TB prevention and care. It aligns with WHO policies and guidance on TB prevention and screening, management of TB and comorbidities, access... to health care, universal health coverage, determinants of TB, TB-associated impairment and disability, social protection, as well as ethics, equity and human rights.
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The 2024 edition reviews more than 50 health-related indicators from the Sustainable Development Goals and WHO’s Thirteenth General Programme of Work. It also highlights the findings from the Global health estimates 2021, notably the impact of the COVID-19 pandemic on life expectancy and healthy l...ife expectancy.
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Despite being a preventable and curable infectious disease, tuberculosis (TB) has continued to elude global controll efforts. In 2023, 8.2 milion people with TB were diagnosed and notified to the WHO, the hightest number ever reported since WHO began tracking.
The world has been turned on its head by the coronavirus disease 2019 (COVID-19) pandemic. This has provided a stark wakeup call on the severe under-financing of health systems around the world. It has laid bare the inequalities and limitations in the capacities of countries at all levels of develop...ment to prevent major health crises or respond to them. But it doesn’t have to be this way.
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A aplicação da tecnologia digital de saúde está crescendo rapidamente na África, com o
objetivo de melhorar a prestação de serviços de saúde e alcançar de forma mais eficaz
comunidades remotas e carentes. A falta de diretrizes e padrões habilitadores em todo o
continente, por outro ...lado, dificulta o compartilhamento de dados de forma significativa em
todo o continente. Considerando isso, os Centros Africanos de Controle e Prevenção de
Doenças (CDC África) estabeleceram uma força-tarefa de 24 membros para fornecer
experiência e orientação no desenvolvimento de diretrizes e padrões da AU HIE. Os membros
da força-tarefa eram especialistas no assunto que trabalhavam na África e
internacionalmente na coleta, análise e troca de informações de saúde. Alguns desses
especialistas estiveram envolvidos em consultas anteriores sobre a definição da estratégia de
sistemas de informação de saúde do CDC África. Um presidente, copresidente e secretário
foram eleitos para envolver os membros da força-tarefa em diferentes grupos de trabalho
técnicos.
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Este documento traz recomendações para a implementação de planos operacionais em redes de serviços de saúde, tanto na atenção primária (incluindo assistência domiciliar) quanto em hospitais, para reorganizar a entrega dos serviços e ganhar eficiência na gestão e expansão da oferta de l...eitos, considerando a complexidade crescente dos casos. Essas recomendações concentram-se na gestão dos serviços de saúde para reorganizar e expandir a resposta desses serviços de acordo com a evolução da epidemia. Este documento de trabalho será atualizado na medida em que novos conhecimentos e evidências em relação ao SAR-Cov2 forem disponibilizados, e as recomendações fornecidas devem ser adaptadas para a realidade de cada país, considerando-se as características do respectivo sistema de saúde.
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DESENHO DESTE FORMULÁRIO DE NOTIFICAÇÃO DE CASO (CRF). Este CRF inclui 3 módulos: Módulo 1: deve ser preenchido no primeiro dia de internação na unidade de saúde. Módulo 2: deve ser preenchido diariamente durante a internação hospitalar e pelo número de dias que os recursos permitirem. C...ontinue a acompanhar os pacientes que são transferidos para outras alas. Módulo 3: deve ser preenchido na alta ou no caso de óbito.
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