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1
La page du site VIDAL intitulée « Paludisme : traitement – Recommandations » présente les recommandations actuelles pour la prise en charge du paludisme. Elle détaille les différents traitements selon le type de paludisme (P. falciparum ou non), la gravité de l'infection (simple ou sévère
...
) et le contexte (enfants, femmes enceintes, zones de résistance). Elle aborde également les protocoles de traitement, les médicaments recommandés (comme l'artéméther-luméfantrine ou l'atovaquone-proguanil), ainsi que les précautions à prendre en cas d’automédication ou de voyage en zone endémique.
more
This Implementation Kit (I-Kit), developed by the Health Communication Capacity Collaborative (HC3), helps national and local stakeholders to design country-specific social and behavioural change communication (SBCC) campaigns that address the threat posed by substandard, spurious, falsified and fal
...
sely labelled (SSFFC) malaria medicines. These poor-quality medicines endanger lives by failing to treat malaria effectively, undermine health systems, and contribute to drug resistance.
The I-Kit provides practical guidance and resources in six sections, including global examples, campaign design elements, media engagement strategies and tools for knowledge sharing. It is intended for health promotion officers, drug regulators, communication specialists and global health partners. Drawing heavily on experiences in Nigeria, the I-Kit promotes evidence-based, context-sensitive SBCC interventions to safeguard communities against SSFFC malaria medicines and enhance treatment outcomes.
more
Access to safe, effective and quality-assured health products and technologies is crucial for achieving universal health coverage and primary health care goals. The continued growth of the aging population; increasing burden of noncommunicable diseases; growing burden of mental health issues; climat
...
e change; shifting patterns of vector borne diseases, fungal disease and waterborne diseases; antimicrobial resistance; and new infectious hazards create an ongoing need for equitable access to safe, effective and quality-assured health products and technologies, and renewed investments in research and development for innovative health products and technologies.
The coronavirus pandemic exposed the inequalities in access to health products, highlighting the need for longer-term strategies to strengthen access to health products and technologies outside of and in emergency situations. While technological and scientific advances present an opportunity to increase access to health products and technologies, the risk of increasing inequality due to higher prices for new health products and technologies; the persisting problem of substandard and falsified medical products; a lack of skilled workforce in many low- and middle-income countries; and a lack of data for decisionmaking and for measuring progress present significant challenges.
more
Malaria remains a significant public health concern, particularly in sub-Saharan Africa, where the majority of cases and fatalities occur, especially among children under five. Although there was a significant decline in global mortality and incidence between 2000 and 2015, progress has stalled sinc
...
e the late 2010s due to climate change, conflict, drug and insecticide resistance, and the ongoing effects of the pandemic. Economic modelling shows that achieving the Sustainable Development Goal target of reducing malaria incidence by 90% by 2030 could generate substantial economic benefits, including an increase in GDP of $142.7 billion in endemic countries and $80.7 billion in global trade gains. To save lives, strengthen health systems, and drive sustainable economic growth, renewed investments in malaria control and elimination programmes, vaccine deployment, and coordinated international support are essential.
Accessed on 25/08/2025.
more
Pregnant travelers face numerous risks, notably increased susceptibility to or severity of multiple infections, including malaria. Because pregnant women residing in areas non-endemic for malaria are unlikely to have protective immunity, travel to endemic areas poses risk of severe illness and pregn
...
ancy complications, such as low birthweight and fetal loss. If travel to malaria-endemic areas cannot be avoided, preventive measures are critical. However, malaria chemoprophylaxis in pregnancy can be challenging, since commonly used regimens have varying levels of safety data and national guidelines differ. Furthermore, although chloroquine and mefloquine have wide acceptance for use in pregnancy, regional malaria resistance and non-pregnancy contraindications limit their use. Mosquito repellents, including N,N-diethyl-m-toluamide (DEET) and permethrin treatment of clothing, are considered safe in pregnancy and important to prevent malaria as well as other arthropod-borne infections such as Zika virus infection. Pregnant travelers at risk for malaria exposure should be advised to seek medical attention immediately if any symptoms of illness, particularly fever, develop.
more
En 2024, le Cap-Vert et l’Égypte ont été certifiés exempts de paludisme, ce qui prouve qu'il est possible d'éliminer la maladie avec une volonté politique et des ressources adaptées. Cependant, en Afrique, où se concentrent 95 % des cas mondiaux et 97 % des décès (en 2023), les progrès
...
stagnent et l’objectif d’élimination d’ici 2030 est menacé. Les principaux obstacles sont le déficit de financement, la résistance aux insecticides et aux médicaments, l'expansion du moustique Anopheles stephensi, le changement climatique, les crises humanitaires et la croissance démographique. Pour inverser la tendance, l’Afrique doit accélérer le déploiement de nouveaux outils (moustiquaires de nouvelle génération, vaccins), renforcer la mobilisation des ressources nationales et diversifier les financements. Une feuille de route de l’Union africaine vise à transformer ces engagements en actions concrètes pour éliminer le paludisme et ses conséquences sanitaires et économiques.
Accessed 27/08/2025.
more
BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022 (2025 interim update)
The purpose of the 2025 interim update of the guidelines was to update our recommendations based on new evidence since the last update, including: (i) incorporating new evidence related to injectable therapy including frequency of viral load monitoring and use of long-acting cabotegravir/rilpivirine
...
in non-virally suppressed people; (ii) removal of abacavir from first-line recommendations for most and a recommendation to switch away from abacavir where clinically appropriate; (iii) removal of the CD4 caveat for first-line dolutegravir/lamivudine use; (iv) updated recommendations for people with NRTI resistance. These changes, with the supporting evidence, are highlighted in green.
more
Understand HIV transmission, prevention strategies, and treatment advances including antiretroviral therapy and PrEP. Access medical lectures and research updates on YouTube from Harvard, medical professionals, and health organizations covering drug resist
...
ance, vaccine development, and co-infections.
more
PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m
...
easure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across 137 geographic regions. Samples were obtained from 1,052 locations in 104 countries (representing all continents and 36 countries not previously studied for API contamination) and analyzed for 61 APIs. Highest cumulative API concentrations were observed in sub-Saharan Africa, south Asia, and South America. The most contaminated sites were in low- to middle-income countries and were associated with areas with poor wastewater and waste management infrastructure and pharmaceutical manufacturing. The most frequently detected APIs were carbamazepine, metformin, and caffeine (a compound also arising from lifestyle use), which were detected at over half of the sites monitored. Concentrations of at least one API at 25.7% of the sampling sites were greater than concentrations considered safe for aquatic organisms, or which are of concern in terms of selection for antimicrobial resistance. Therefore, pharmaceutical pollution poses a global threat to environmental and human health, as well as to delivery of the United Nations Sustainable Development Goals.
more
Contains data from World Health Organization's data portal covering the following categories:
Mortality and global health estimates, Sustainable development goals, Millennium Development Goals (MDGs), Health systems, Malaria, Tuberculosis, Child health, Infectious diseases, Neglected Tropical Disea
...
ses, World Health Statistics, Health financing, Tobacco, Substance use and mental health, Injuries and violence, HIV/AIDS and other STIs, Public health and environment, Nutrition, Urban health, Noncommunicable diseases, Noncommunicable diseases CCS, Negelected tropical diseases, Infrastructure, Essential health technologies, Medical equipment, Demographic and socioeconomic statistics, Health inequality monitor, Health Equity Monitor, Child malnutrition, TOBACCO, Neglected tropical diseases, International Health Regulations (2005) monitoring framework, 0, Insecticide resistance, Oral health, Universal Health Coverage, Global Observatory for eHealth (GOe)
more
Esta guía rápida sobre la adaptación de los programas de resistencia a los antimicrobianos (TAP, por su sigla en inglés) se ha elaborado para ayudar los países a iniciar y ejecutar proyectos para enfrentar la propagación de la resistencia a los antimicrobianos en sus territorios. La resistenci
...
a a los antimicrobianos es un problema complejo, con muchos factores que afectan su aparición y propagación, por lo que resulta difícil abordarlo. La guía rápida del proceso de TAP está diseñada para ayudar a los grupos de trabajo de TAP a nivel nacional a aplicar un enfoque de estudio del comportamiento para formular intervenciones apropiadas y factibles a fin de comenzar a combatir la resistencia a los antimicrobianos en sus contextos. La guía proporciona un panorama general de la resistencia a los antimicrobianos y el proceso de TAP, y conduce a los usuarios a lo largo de cinco etapas para evaluar la factibilidad, adquirir una comprensión referencial de los problemas, priorizar los temas que han de tratarse, formular estrategias y ejecutar y evaluar las intervenciones. La guía viene acompañada del Conjunto de Herramientas de TAP. Ejercicios, herramientas y plantillas para facilitar su plan de intervenciones a medida contra la resistencia a los antimicrobianos, que contiene ejercicios y recursos para facilitar cada etapa de formulación del proyecto.
more
Para controlar y eliminar el paludismo (o malaria) es fundamental contar con fármacos antipalúdicos eficaces. Para fundamentar las políticas de tratamiento en los países donde esta enfermedad es endémica, y para garantizar la pronta detección de toda farmacorresistencia y una adecuada respuest
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a a ella, es preciso ejercer una vigilancia continua de la eficacia de estos medicamentos.
more
Malgré ces progrès, le paludisme reste toutefois un problème de santé mondial important, avec environ 282 millions de cas et 610 000 décès en 2024, soit environ 9 millions de cas de plus que l'année précédente. La région Afrique de l'OMS continue de supporter la plus grande partie du farde
...
au, avec 11 pays représentant environ les deux tiers des cas et des décès dans le monde. Les progrès en matière de réduction du taux de mortalité lié au paludisme restent toutefois très insuffisants.
more
Este resumen ejecutivo ofrece una visión general completa de los mensajes clave, los datos y las tendencias del Informe mundial sobre la malaria 2025.
Au cours des trente dernières années, la mortalité des enfants de moins de cinq ans a chuté de près de 60 % au niveau mondial
Objective To determine whether adding urine culture to urinary tract infection diagnosis in pregnant women from refugee camps in
Lebanon reduced unnecessary antibiotic use.
This document is a compilation of all questions, justifications, and sources used to determine the 2021 Global Health Security Index scores for Zambia. For a category and indicator-level summary, please see the Country Profile for Zambia.
