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1
2015 Pipeline Report HIV, Hepatitis C virus (HCV), and Tuberculosis (TB)
Polly Clayden, Simon Collins, Mike Frick, et al.
A. Benzacar; HIV i-BASETREATMENT ACTION GROUP
(2015)
Drugs, Diagnostics, Vaccines, Preventive Technologies, Research toward a cure, and immune-based and gene therapies in development
Asthma is a very commom condition. It cannot be cured, but can controlled with effective medication, good technique, and good monitoring by the patients are having no or few symptoms, no attacks needingg hospital visits
...
and no or little emergency reliever medication use. Another way of assessing asthma control is to do tests that measure the function of your lungs. These tests are sometimes also done to help with the diagnosis of asthma.
more
The Manual for Parasitological Surveillance in Prevention of Reintroduction or Re-establishment of Malaria in Sri Lanka (2019) provides guidelines to health professionals on how to conduct effective malaria surveillance to prevent the reintroduction of the disease in Sri Lanka, which was certified m
...
alaria-free in 2016.
The manual outlines strategies for active and passive case detection, laboratory diagnosis, case investigation, foci investigation, and follow-up measures. It emphasizes targeted screening of high-risk populations, including travelers and migrant workers, and explains the importance of prompt reporting, accurate parasitological confirmation, and coordination between healthcare levels. The overall goal is to maintain Sri Lanka’s malaria-free status by ensuring early detection and rapid response to any imported or locally suspected malaria cases.
more
An integrated approach is particularly important for low-resource settings for efficient use of limited resources. The course contents will include risk factors, clinical course, guidance and protocols for
...
diagnosis, management and referral as needed for NCDs in PHC. SEARO NCD PEN-HEARTS is a series of four courses with the other three courses focusing on Hearts of NCD: an integrated approach to management of NCDs in PHC, diabetic foot care and palliative care that will enable the learner to plan and deliver NCD services.
more
Global Initiative for Chronic Obstructive Lungs Disease
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
(2024)
CC2
The GOLD website is dedicated to providing comprehensive information on Chronic Obstructive Pulmonary Disease (COPD). It offers resources and guidelines for healthcare professionals and public healt
...
h authorities to improve the diagnosis, management, and prevention of COPD worldwide. The site includes the latest reports, strategies, and updates on COPD research, emphasizing evidence-based practices for better patient outcomes. GOLD also provides educational materials, workshops, and support for implementing COPD care programs, aiming to raise global awareness and promote effective treatments for COPD.
more
The article from the European Respiratory Journal discusses the natural history of chronic obstructive pulmonary disease (COPD), emphasizing its increasing global impact on morbidity and mortality. It highlights that while cigarette smoking is a pri
...
mary risk factor, other influences such as environmental exposures and genetics also play significant roles. The article notes that lung function, measured by FEV1 (forced expiratory volume in one second), is a critical indicator of both diagnosis and prognosis. It further explores the impact of exacerbations, comorbidities, and systemic inflammation on disease progression and outcomes. The need for comprehensive patient management, which considers various comorbid conditions and inflammatory factors, is emphasized to improve clinical outcomes and reduce healthcare costs.
more
The Mediclinic article on silicosis provides an overview of this occupational lung disease caused by inhaling silica dust. It explains that inhaled silica particles lead to lung scarring and nodule formation, progressively impairing breathing. The a
...
rticle outlines symptoms such as shortness of breath, severe cough, fatigue, loss of appetite, chest pains, and fever. Diagnosis involves a medical examination, detailed occupational history, lung function tests, and imaging like chest X-rays or CT scans to detect lung scarring and nodules. While silicosis is irreversible with no specific cure, management focuses on preventing further silica exposure and treating complications. Preventive measures include maintaining high occupational health standards to control silica dust exposure.
more
HIV & AIDS Treatment in Practice
Issue 203
Diagnosis and Management of Systemic Lupus Erythematosus
HIV & AIDS Treatment in Practice No.202
Journal of Infectious Diseases and Therapeutics, 2013, 1, 17-24
This guide includes information relevant for tuberculosis (TB) program and laboratory managers, as well as Ministry of Health officials across disease programs interested in establishing integrated solutions for specimen referral. Though TB-focused
...
in name, it offers integration-oriented assessment, design, and monitoring guidance related to improving coordination and efficiency, and is relevant for other programs as well. Country case studies include viral load and early infant diagnosis (EID) in Uganda and EID in Ethiopia.
more
General practitioners and pediatricians must know the signs and
symptoms of possible pediatric cancer.
HIV & AIDS Treatment in Practice No. 188
Direct acting antivirals (DAAs) have revolutionized treatment for hepatitis C. Combi-
nations of DAAs can cure infection with HCV in 12 weeks, are highly effective and
have limited
...
side-effects. Affordability of DAAs has improved significantly, but access remains lim-
ited. Initially, due to their high prices, affordability of DAAs was limited in high-, middle- and low-
income countries alike. Now there is a divide between those countries where, because of intellectual
property barriers, prices have remained (very) high and other countries where generics are, or can be,
available at much lower prices. The result is a dual market
more
2nd edition. These guidelines include several notable changes from the first edition. For cutaneous leishmaniasis, ketoconazole has been removed from the list of treatment options; the number of Leishmania species for which there is strong evidence
...
for the efficacy of miltefosine has increased from two to four; and the recommendation for intralesional antimonials is now strong. For mucosal leishmaniasis there is now a strong recommendation for use of pentavalent antimonials with or without oral pentoxifylline. For visceral leishmaniasis, the strong recommendations for use of pentavalent antimonials and amphotericin B deoxycholate are now conditional.
more
Cognitive Training for Schizophrenia in Developing Countries: A Pilot Trial in Brazil (Clinical Study)
Pontes LM, Martins CB, Napolitano IC, Fonseca JR, Oliveira GM, Iso SM, Menezes AK, Vizzotto AD, di Sarno ES, Elkis H.
Schizophrenia Research and Treatment
(2013)
CC
Cognitive deficits in schizophrenia can massively impact functionality and quality of life, furthering the importance of cognitive training. Despite the development of the field in Europe and in the
...
United States, no programmes have been developed and tested in developing countries. Different cultural backgrounds, budget restrictions, and other difficulties may render treatment packages created in high income countries difficult for adoption by developing nations. We performed a pilot double-blind, randomized, controlled trial in order to investigate the efficacy and feasibility of an attention and memory training programme specially created in
a developing nation. The intervention used simple, widely available materials, required minimal infrastructure, and was conducted in groups.The sample included seventeen stable Brazilians with schizophrenia. Sessions were conducted weekly during five months. The cognitive training group showed significant improvements in inhibitory control and set-shifting over time. Both groups showed improvements in symptoms, processing speed, selective attention, executive function, and long-term visual memory. Improvements were found in the control group in long-term verbal memory and concentration. Our findings reinforce the idea that cognitive training in schizophrenia can be constructed using simple resources and infrastructure, facilitating its adoption by developing countries, and it may improve cognition.
more
