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Publication Years
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Toolboxes
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The World Health Organization (WHO) fact sheet on ambient (outdoor) air quality and health highlights the significant health risks posed by outdoor air pollution. It reports that in 2019, ambient air pollution was responsible for approximately 4.2 million premature deaths globally, primarily due to
...
exposure to fine particulate matter (PM2.5), which leads to cardiovascular and respiratory diseases, as well as cancers. The fact sheet emphasizes that 99% of the global population lived in areas exceeding WHO air quality guidelines in 2019, with low- and middle-income countries bearing the highest burden. To mitigate these health impacts, WHO advocates for policies and investments that promote cleaner transportation, energy-efficient housing, improved waste management, and access to clean household energy.
more
The aim of the present study was to predict which patients with severe or difficult-to-treat asthma are at highest risk for healthcare utilisation can be predicted so as to optimise clinical management. Data were derived from 2,821 adults with asthm
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a enrolled in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. Multiple potential predictors were assessed at baseline using a systematic algorithm employing stepwise logistic regression. Outcomes were asthma-related hospitalisations or emergency department (ED) visits within 6 months following baseline.
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Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, with airway reversibility. Management of chronic inflammation with anti-asthma medication improves asthma control and quality of li
...
fe. The aim of this journal is to provide an evidence-based approach for chronic asthma management in young children and adolescents and provide guidance on the use of new asthma drugs in children.
For that, the South African Childhood Asthma Working Group (SACAWG) convened in January 2017. The asthma treatment task group reviewed the available scientific literature and international asthma treatment guidelines. The evidence was then graded according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system and recommendations were made based on scientific evidence and local context. Asthma management recommendations were made for children ˂6 years of age and older children and adolescents, as well as for stepping up and stepping down of therapy. This review does not include biologics or novel asthma drugs, which are covered in another CME article in this edition of SAMJ.
The final conclusions are that it is important to ensure good response, treatment and adherence, type of medication, device and checking of technique are all critical. Stepping up of therapy should be done only after ensuring good adherence and technique. Once therapeutic response is achieved, medication administration has to be stepped down to improve ease of use and avoid unnecessary side-effects.
more
Most of the global burden of sepsis occurs in low- and middle-income countries (LMICs), but the prevalence and etiology of sepsis in LMICs are not well understood. In particular, the lack of laboratory infrastructure in many LMICs has historically precluded an assessment of the pathogens leading to
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sepsis. A recent systematic review found that data describing antimicrobial resistance were absent for 43% of countries in Africa, and only two countries have national antimicrobial resistance plans. In addition, small studies have identified indiscriminate antibiotic use both in and out of hospital settings in sub-Saharan Africa. The absence of microbiological data and lack of antibiotic stewardship complicate sepsis management and almost certainly worsens outcomes, particularly in low-resource systems. The purpose of this study was to examine the prevalence, etiology, and outcomes of sepsis among a cohort of critically ill patients in a referral hospital of Malawi, with a focus on the prevalence of culture-confirmed bacteremia and urinary tract infections.
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The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling and consolidating the latest World Health Organization recommendatio
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ns on the subject into a single guide, the aim is to create a reference and consultation document that is frequently used, and that unifies and standardizes the comprehensive management of TB/HIV co-infection in healthcare facilities based on the principle of “two diseases, one patient.” It also seeks to support the updating of national standards and guidelines on co-infection and to complement the coordinated work that must exist between TB and HIV prevention and control programs at all levels, within the framework of the twelve internationally recommended TB/HIV collaborative activities.
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The presentation titled "Malaria Capacity Building Initiative" outlines efforts led by the WHO and partner organizations to strengthen the skills and systems needed to fight malaria globally. It highlights the need for a coordinated, long-term strategy to build human resource capacity in malaria-end
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emic countries—especially among national malaria control programs, frontline health workers, NGOs, and WHO staff. The document reviews past and current training activities, such as workshops on case management, entomology, vector control, epidemiology, and planning. It emphasizes the development of standardized training materials and competency frameworks, the role of national and regional training centers, and the use of blended learning methods (e.g., e-learning and in-person sessions). The goal is not just to deliver training, but to build sustainable capacity through partnerships, continuous improvement, quality assurance, and integration into health systems. It also calls for better coordination, tracking of trained personnel, and engagement of ministries of finance to ensure long-term support.
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Malaria is an infection caused by Plasmodium species endemic to most parts of Africa, South America, East Asia, and parts of Europe and the Middle East. At least 10 to 30 thousand of the 125 million travelers to these areas are infected each year. All visitors to endemic areas should receive counsel
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ing on malaria risk, mosquito bite avoidance, and tailored chemoprophylaxis based on their medical histories and travel plans. This activity reviews the evaluation and management of chemoprophylaxis of malaria and highlights the role of the healthcare team in improving care for patients with potential exposure to this condition.
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The YouTube channel "Diabetes Africa" serves as a platform to unite healthcare professionals, entrepreneurs, and decision-makers across Africa and its diaspora with the goal of eradicating diabetes. The channel focuses on identifying and promoting innovative solutions and champions in the fight agai
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nst diabetes. Its content includes discussions on diabetes management, addressing inequalities in care, and exploring the relationship between diabetes and various health conditions.
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The article "Best (and Worst) Oatmeal for Type 2 Diabetes" from Everyday Health discusses the benefits of incorporating oatmeal into a diabetes-friendly diet. It emphasizes that oatmeal, being rich in fiber and essential minerals like magnesium, potassium, and iron, can aid in blood sugar control, s
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upport heart health, and assist with weight management.
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The document "Cystic Fibrosis Key Findings 2023 for Care Providers" by the Pennsylvania Department of Health summarizes recent findings and insights related to cystic fibrosis (CF). It highlights key statistics on the prevalence and outcomes of CF, emphasizes best practices for patient care, and pro
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vides recommendations for healthcare providers. The document discusses improvements in treatment protocols, advances in medical research, and strategies to enhance patient quality of life. It also includes guidance on early detection, genetic testing, and comprehensive management plans to support affected individuals and their families.
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The article "Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review" analyzes factors contributing to poor asthma control in African youth. Based on studies conducted between 2014 and 2019 in Nigeria, Uganda, and South Africa, the review identifies key
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challenges such as limited access to asthma diagnosis, inadequate use of inhaled corticosteroids, and environmental and socio-economic factors. It finds that urban living, older age, and concurrent allergic conditions significantly affect asthma management. The study emphasizes the need for improved diagnostic tools, better access to treatment, and tailored public health interventions to enhance asthma outcomes in African children.
more
Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The diagnosis of asthma in young children is limited by the inability to perform objective lung function testing in this group of patients and the wi
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de variety of conditions that can phenotypically present with asthma-like symptoms.
This article provides an evidence-based approach for clinicians to accurately diagnose asthma in young children and to assess the level of control to guide therapeutic decisions.
The South African Childhood Asthma Working Group (SACAWG) convened in January 2017 with task groups, each headed by a section leader, constituting the editorial committee on assessment of asthma epidemiology, diagnosis, control, treatments, novel treatments and self-management plans. The asthma diagnosis and control task groups reviewed the available scientific literature and assigned evidence according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system, providing recommendations based on current evidence.
more
Asthma is the most common chronic illness of childhood. The prevalence is rising and the mortality and morbidity from asthma are unacceptably high in South Africa. This article emphasizes the importance to make a correct diagnosis based, most importantly, on the clinical history and supported by inv
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estigations. Further, the appropriate drug and device must be chosen to achieve good asthma control. It explains that patients must be followed up regularly and their asthma control must be assessed so that the treatment can then be adjusted according to the level of control. Additionally, Asthma education and adherence are important components of management of the condition.
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Tanzania has an estimated 2.9 million adults with diabetes, 35% of whom are undiagnosed, and over 22,000 people living with type 1 diabetes. While the 2023 Universal Health Insurance law aims to improve access to care, only 15% of people are insured. Over 700 clinics provide diabetes care and offer
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free insulin to children and young adults. However, challenges remain regarding insulin availability, diagnostics, patient education and the healthcare workforce. Community engagement, training and policy advocacy are essential for improving diabetes management and achieving universal health coverage.
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The WHO Health Security Learning Platform (HSLP) is an online training hub that provides courses and toolkits to strengthen countries’ capacities in public-health preparedness, emergency response, and implementation of the International Health Regulations (IHR). It offers self-paced modules and pr
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actical training materials on topics such as outbreak response, points-of-entry management, One Health, and laboratory preparedness, helping health professionals build essential skills for global health security.
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The webpage “Emergency Response Framework” on the OpenWHO platform provides learning materials that introduce the World Health Organization’s (WHO) Emergency Response Framework (ERF). The framework explains how WHO organizes and manages responses to public health emergencies, including how eve
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nts are assessed, graded and coordinated at global, regional and country levels. The training content presents key concepts such as emergency management principles, the Incident Management System, coordination structures, and the roles and responsibilities of WHO staff and partners during health crises. Overall, the webpage aims to help health professionals and responders understand how WHO coordinates emergency operations and ensures a structured, timely and effective response to outbreaks and other health emergencies.
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Management of pneumonia in community settings
recommended
World Health Organization
(2004)
