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In this guide, the African Palliative Care Association (APCA) has put together evidence‑based information on the use of specific opioids commonly used in the management of moderate‑to‑severe pain to manage both cancer and non‑cancer pain. APCA hopes that this guide will be a useful tool i
...
n aiding health professionals at all levels of healthcare delivery to assess and manage pain using opioids. All opioids included in this guide are listed on the WHO model list of essential medicines but we remind readers that oral morphine is the standard opioid of choice for managing moderate‑to‑severe pain and we recommend that it should be made available at all times.
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Reported cholera cases rose by 5% and deaths by 50% in 2024 compared to 2023, with more than 6000 people dying from a disease that is both preventable and treatable. Whi
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le these numbers are themselves alarming, they are underestimates of the true burden of cholera.
Weekly epidemiological record WER No 36, 2025, 100, 347–364
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Policy Brief. Good practice statement: When planning and implementing a response for HIV, viral hepatitis and sexually transmitted diseases (STIs), policy-makers and providers should be aware that
counselling behavioural interventions aimed to change behaviours to reduce risks associated
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ese infections for key populations have not been shown to have an effect on HIV, viral
hepatitis and STIs’ incidence nor on risk behaviour such as condom use and needle/syringe
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nes key ethical, human rights and technical considerations for countries adopting digital technologies for health, detailing human rights risks, norms and standards, and provides a practical checklist for assessment.
The Toolkit serves as a quick reference guide for UNDP staff, governments, partners, technology developers, and civil society organizations, designed to provide practical guidance for implementing ethical digital health solutions by distilling and structuring the in-depth information from the broader UNDP Guidance into six easy-access modules. Each module addresses a specific key issue by outlining definitions, ethical principles, key considerations, and recommendations that align with the comprehensive framework established by the UNDP Guidance.
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The primary audience for this guideline includes policy-makers or service providers who are responsible for developing national and local health-care protocols and policies related to care during pregnancy, childbirth and the postnatal period, and those directly providing care to women during pregna
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These guidelines update earlier WHO recommendations to maximize the HIV prevention impact of safe VMMC services and aim to guide the transition to the sustained provision of interventions with a focus on the health and well-being of both adolescent boys and men.
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This report describes efforts in nine countries, supported by the 2gether 4 SRHR programme and other partners, highlighting the results achieved and learning on improving the health and wellbeing of adolescent and young mothers and their families. Key insights include the importance of responsive se
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rvice delivery and social support as well as service provision across sectors.
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ng on their strengths, FBOs can potentially serve as useful platforms for engaging men and other priority populations, promoting greater demand, uptake, and retention in care.
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This document aims to provide public health authorities in European Union and European Economic Area (EU/EEA) countries with guidance for improved preparedness planning taking the lessons that have been identified through various activities in the context of recent public health crises (e.g. COVID-1
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9 pandemic, mpox multi-country outbreak 2022–23) and translating them to concrete advice. This document, together with the ECDC recommendations on the implementation of public health and social measures (PHSMs) for health emergencies and pandemics published in 2024, form a package of concrete recommendations for preparedness planning for the EU/EEA countries. Lessons learned primarily from the response to the COVID-19 pandemic, but also from the response to the multicountry mpox outbreak in 2022–23, were collected through various activities from Member States, the European Commission, the World Health Organization (WHO) and the WHO Regional Office from Europe. We have then presented these in the form of specific recommendations for planners within each phase of the continuous cycle of preparedness (Anticipation, Response and Recovery), following a prototype structure of a preparedness and response plan. In each section, we have presented a relevant example from a Member State or international organisation to illustrate their practice or attempt to implement lessons after COVID-19 or the mpox outbreak. These examples were identified either through literature review or communication with representatives of the countries within ECDC’s network for Preparedness and Response.
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The document Integrated Disease Surveillance and Response Technical Guidelines, Booklet Four: Sections 8 and 9 (Third Edition, 2019) provides guidance for strengthening public health surveillance and response systems in the WHO African Region. It focuses on monitoring, supervision, evaluation, and f
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eedback mechanisms to improve the performance and quality of Integrated Disease Surveillance and Response (IDSR) systems. The text outlines key surveillance core functions—such as case detection, reporting, data analysis, outbreak investigation, preparedness, response, and feedback—and introduces indicators to measure system effectiveness, including timeliness, completeness, and data quality. Additionally, it discusses the implementation of electronic IDSR (eIDSR) to enhance real-time reporting and outbreak management. Overall, the booklet aims to strengthen early detection, rapid response, and health security capacity across all levels of the health system.
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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
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ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
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Despite gains in childhood survival, more effort is needed to improve the well-being of children with developmental delays and disabilities. All children, including children with developmental delays and disabilities, need nurturing care. Nurturing care can contribute to preventing developmental del
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ays and protect children who are exposed to risk factors, as well as improve functioning and long-term outcomes for children with developmental disabilities. This Brief outlines why and how nurturing care is relevant for children with developmental delays and disabilities. Recognizing that these children have diverse needs requiring different levels of coordinated and family-centred support, it recommends a set of actions to strengthen policies, services, communities and caregiver capabilities so that these children receive nurturing care.
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