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1
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
National Policy
This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi
...
ng on their strengths, FBOs can potentially serve as useful platforms for engaging men and other priority populations, promoting greater demand, uptake, and retention in care.
more
A Toolkit on Positive Prevention for People Living with HIV. The stories contained in the Flipchart are of real people in Malawi living and affected by HIV/AIDS. Each story follows the theme for a particular session in the Guide. The questions related to each story are found within the Facilitator G
...
uide. Activities are also included for each thematic session. These resources were developed as part of the Malawi BRIDGE Project, and as part of the Positive Prevention campaign, which aimed at creating an HIV/AIDS prevention response that recognizes the needs and desires of PLHIVs by providing them with information to live healthy, and addressing the psycho-social well-being including family planning option
more
The paper “Artificial Intelligence for Public Health Surveillance in Africa: Applications and Opportunities” examines how artificial intelligence (AI) can improve public health systems across Africa, particularly in low-resource settings. It explores how machine learning and other AI techniques
...
are being used for disease detection, outbreak prediction, real-time surveillance, and health resource management.
The authors focus on major public health challenges such as HIV, cholera, Ebola, measles, tuberculosis, malaria, COVID-19, and mental health. Through numerous case studies, the paper shows that AI can enhance the accuracy and speed of disease detection, predict outbreaks more effectively than traditional methods, support vaccination strategies, and optimize healthcare resource allocation. At the same time, it discusses important barriers to implementation, including limited data quality, infrastructure constraints, ethical concerns, and shortages of technical expertise.
Overall, the paper highlights AI’s strong potential to strengthen disease surveillance and health outcomes in Africa while emphasizing the need for careful integration, improved data systems, and supportive policy frameworks.
more
The document “Mpox Continental Response Plan 2.0” outlines the strategy developed by the Africa Centres for Disease Control and Prevention (Africa CDC) in collaboration with the World Health Organization (WHO) to respond to the ongoing mpox outbreak across Africa. The plan describes coordinated
...
actions to strengthen surveillance, laboratory capacity, case detection and contact tracing in affected countries. It also focuses on improving access to vaccines, diagnostics and treatment, supporting healthcare systems, and enhancing risk communication and community engagement. In addition, the document highlights the importance of regional and international cooperation, resource mobilization and technical support to help African countries control the outbreak and prevent further spread. Overall, the plan serves as a continental framework to guide a coordinated public health response to mpox in Africa.
more
Program implementation orientation and training Day 1
medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC
commitments in the largest HIV epidemic in the world leads to increased incidence and mortality
and threatens decades of progress in KZN, South Africa. Rest
...
oring funding within 12 months
and increasing efficiency of HIV interventions can reestablish KwaZulu Natal province, South
Africa’s trajectory toward EHE goals.
more
This document consolidates, for the first time, WHO recommendations on the prevention, testing, treatment and monitoring of hepatitis B and C, and includes testing strategies for hepatitis D. Drawing on a decade of evidence-based guidance issued between 2015 and 2025, it provides a single, practical
...
handbook to support global progress toward eliminating viral hepatitis by 2030.
The document also highlights simplified service delivery models that promote decentralization, integration with primary care and related programmes such as HIV and tuberculosis, as well as task sharing and differentiated care to expand access and improve efficiency. It further underscores the need for robust data and monitoring systems to support effective programme implementation.
more
The 2025 Impact Report summarises Malaria Consortium's year in numbers and includes a message from the Chief Executive.
As countries presented their epidemiological and programmatic situations, and WHO summarized the global status of HAT, the central message was one of satisfaction with the remarkable progress towards elimination. A historically low number of cases was reported, despite maintaining high levels of act
...
ive and passive screening in all accessible at-risk areas. In addition, 10 countries have been officially validated for the elimination of HAT as a public health problem.
Time was also devoted to reviewing progress and challenges in the areas of diagnostics, therapeutics and vector control interventions.
more
The compendium compiles practical case studies on the use of Geospatial Artificial Intelligence (GeoAI) to enhance disaster risk reduction and emergency response across diverse geographic and institutional contexts.
The compendium features selected case studies submitted by twenty-seven Regional Su
...
pport Offices (RSOs) working across Asia, Africa, Latin America, and Europe. These examples highlight how GeoAI, is being used to forecast floods, map wildfire risk, assess landslide susceptibility, monitor droughts, and support emergency response. Each project demonstrates how cloud-based platforms and machine learning tools help governments act faster and more precisely when disaster strike.
more
This toolkit lays out a framework for a waterborne disease investigation and consolidates resources to assist investigation activities.
The Waterborne Disease Outbreak Investigation Toolkit was designed to assist state and local health departments in conducting waterborne disease outbreak invest
...
igations. Using experiences of epidemiologists at the state and local levels, this toolkit describes best practices in preparing for, identifying, and responding to a waterborne disease outbreak.
more
Une note d'orientation interagencesur la collaboration avec les communautés des zones à forte densité pour planifier des approches locales de prévention et de gestion de la COVID-19.
First Global Patient Safety Challenge Clean Care is Safer Care
The WHO Guidelines on Hand Hygiene in Health Care provide health-care workers (HCWs), hospital administrators and health authorities with a thorough review of evidence on hand hygiene in health care and specific recommendations to impro
...
ve practices and reduce transmission of pathogenic microorganisms to patients and HCWs. The present Guidelines are intended to be implemented in any situation in which health care is delivered either to a patient or to a specific group in a population. Therefore, this concept applies to all settings where health care is permanently or occasionally performed, such as home care by birth attendants.
more
Including Therapeutic Food, Dietary Vitamin and Mineral Supplementation - 2nd edition
Recommendations to develop guidelines on community-based rehabilitation (CBR) were made during the International Consultation to Review Community-based Rehabilitation which was held in Helsinki, Finland in 2003. WHO; the International Labour Organization; the United Nations Educational, Scientific a
...
nd Cultural Organization; and the International Disability and Development Consortium – notably CBM, Handicap International, the Italian Association Amici di Raoul Follereau, Light for the World, the Norwegian Association of Disabled and Sightsavers – have worked closely together to develop the Community-based rehabilitation guidelines. More than 180 individuals and representatives of nearly 300 organizations, mostly from low-income and middle-income countries around the world, have been involved in their development.
more
