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Time has seen management for Cystic Fibrosis (CF) advance drastically, most recently in the development of the disease-modifying triple combination therapy ivacaftor/tezacaftor/elexacaftor. There is currently limited evidence regarding both the global epidemiology of CF and access to this transforma
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tive therapy - and therefore where needs are not being met. Therefore, this study aims to define gaps in access to CF treatment. The results show that a significant CF patient burden exists in countries where disease-modifying drugs are unavailable, and final figures are likely underestimates. This analysis shows the potential to improve rates of diagnosis and treatment for CF, so a higher percentage of patients receive the most effective triple combination treatment.
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Facilitators can be a mix of doctors, trainers of integrated management of childhood illness (IMCI), nutritionists, public health officers (or otherwise according to each country’s situation) and needs of individual countries. Some countries may
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consider it important to include a doctor in the team to ensure that certain components such as correct identification of danger signs, counselling on developmental milestones and some of the elements of feeding. Whatever the composition of the teams, facilitators should have good training, experience and good communication skills.
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Digital health technology can make health systems more efficient and sustainable, facilitating the provision of high-quality
care across a wide range of contexts and for diverse population health needs. The pace of innovation in digital health i
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s
rapid and constant, with new interventions being developed, implemented, tested and refined against a diversity of contexts,
constraints and challenges to address a variety of health and health system needs.
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This is a moment of reckoning in the fight against HIV, tuberculosis (TB) and malaria. For our Eighth Replenishment, the Global Fund needs US$18 billion to save 23 million lives, cut the death rate from the three diseases by 64% and help build a hea
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lthier, safer and more equitable world.
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Overall, harmonisation and innovation should be the
focus of the future direction of DAH and the creation of
a healthy global community. The world needs all hands
on deck if it were to move towards achieving the SDGs,
addressing global health in
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equalities and improving the
welfare of the global population, while ensuring that no
one is left behind.
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The most packed schedule of cyclical replenishments in global health multilateral institutions has the potential to also clash with competing interests fuelled by a packed election calendar. But health imperatives are not a winner gets all scenario. The article provides a perspective on what
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needs to be done so as to reach out to all interests without compromising on the mission of tackling global health threats. It focuses on the 8th Grant Cycle of the Global Fund and offers suggestions on the way forward.
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It was a difficult time to be a child in 2024. With deepening violent conflict, climate shocks and poverty, children faced skyrocketing needs while the resources to respond continued to shrink.
But as this year’s Annual Report shows, across mo
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re than 190 countries and territories, UNICEF was there, saving and uplifting the lives of millions of children – even in the hardest-to-reach places. Together with our partners, we delivered clean water and sanitation, protection and psychosocial support, health, nutrition, and immunization services, and education and skills development.
The world in 2025 continues to be one of significant political shifts and volatility, economic uncertainty and deepening humanitarian crises. To succeed, UNICEF must be at its best.
But announced and anticipated funding cuts are limiting UNICEF’s ability to reach millions of children in dire need. These new cuts are creating a global funding crisis that will put the lives of millions of additional children at risk.
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Community led-monitoring is based on the principle that «Nothing that is done for us should
be done without us”. The combination of this principle with evidence shows that community-led
monitoring is an important driver of improved service delivery and health outcomes that
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needs to
be re-emphasized. Thus, the community must participate at all stages of the fight against malaria.
This guide will be useful to CSOs working in the field of malaria in the conduct of community-led
monitoring of activities efficiently and allow these CSOs to know their role and responsibilities in this
exercise at each key stage. This guide will also provide CSOs and communities affected by malaria
with templates of monitoring tools adapted to key malaria programs.
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Brief Introduction Malaria Vaccine Training. For countries planning malaria vaccine introduction, WHO has developed training packages of slide sets on key topics for health workers in English and French that can be downloaded and customized to meet specific country
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needs:
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Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents an
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d young adults. However, there needs to be a focus on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
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We are pleased to offer the NCD kit online training course for emergency managers and technical staff in emergencies to ensure rapid, adequate and cost-effective use of the existing Noncommunicable Disease (NCD) kit in emergency health operations to reduce the vulnerability of affected communities a
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nd address their priority health needs. The NCD kit is a pre-packed set of essential medicines and medical devices to meet priority noncommunicable disease (NCD) needs of an outreach population of 10 000 people for three months in emergencies, when medical facilities and regular supply has been disrupted. The training aims to assist all those involved in leading and coordinating health emergency operations, assessing the needs, planning for supplying, implementing and monitoring the continuity of essential NCD services at all levels of emergency management.
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Differentiated Service Delivery
recommended
Differentiated service delivery (DSD), previously referred to as differentiated care, is a client-centred approach that simplifies and adapts HIV services across the cascade to reflect the preferences, expectations and needs of people living with an
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d affected by HIV, while reducing unnecessary burdens on the health system
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These messages may be used as stand-alone resources, and also could be used as a supplement to The Essential Package, a comprehensive set of tools and guides for program managers and service providers supporting programs that address the unique needs
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and competencies of vulnerable children in a holistic way.
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A Training Manual for Para-Social Workers. A Project of the Social Work HIV/AIDS
Partnership for Orphans Vulnerable Children in Tanzania. This training presentation is continually being evaluated and updated to
reflectcurrent needs and best practi
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ces. It should be viewed as work in progress
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The 2026 appeal seeks nearly US$ 1 billion to respond to 36 emergencies worldwide, including 14 Grade 3 emergencies requiring the highest level of organizational response. These emergencies span sudden-onset and protracted humanitarian crises where health
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needs are critical.
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A guide to management in Primary Health Care. A practical, instructive training guide that has proven its capacity to improve the managerial skills of middle-level health workers responsible for the management or supervision of health services. Presented as an activity-centered working guide, the bo
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ok uses numerous questionnaires, exercises, practical examples, illustrations, charts, and sample forms to help readers relate advice and suggestions to their own daily problems. Emphasis is placed on ways to improve the management of health services provided by full-time, qualified staff. The guide features 18 chapters presented in four main parts, any one of which can be studied separately or as part of the whole, according to individual learning needs.
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Maintaining proper storage conditions for health commodities is vital to ensuring their quality. Product expiration dates are based on ideal storage conditions and protecting product quality until their expiration date is important for serving customers and conserving resources. Guidelines for the S
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torage of Essential Medicines and Other Health Commodities is a practical reference for those managing or involved in setting up a storeroom or warehouse. The guide contains written directions and clear illustrations on receiving and arranging commodities; special storage conditions; tracking commodities; maintaining the quality of the products; constructing and designing a medical store; waste management; and resources. It was written to meet the needs of district-level facilities; however, the guidelines and information it contains apply to any storage facility, of any size, in any type of environment.
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Humanitarian emergencies result in a breakdown of critical health-care services and often make vulnerable communities dependent on external agencies for care. In resource-constrained settings, this may occur against a backdrop of extreme poverty, malnutrition, insecurity, low literacy and poor infra
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structure. Under these circumstances, providing food, water and shelter and limiting communicable disease outbreaks become primary concerns. Where effective and safe vaccines are available to mitigate the risk of disease outbreaks, their potential deployment is a key consideration in meeting emergency health needs. Ethical considerations are crucial when deciding on vaccine deployment. Allocation of vaccines in short supply, target groups, delivery strategies, surveillance and research during acute humanitarian emergencies all involve ethical considerations that often arise from the tension between individual and common good. The authors lay out the ethical issues that policy-makers need to bear in mind when considering the deployment of mass vaccination during humanitarian emergencies, including beneficence (duty of care and the rule of rescue), non-maleficence, autonomy and consent, and distributive and procedural justice
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Updated WHO/WEDC Technical Notes on WASH in Emergencies
recommended
World Health Organization; Water Engineering Development Centre
World Health Organization
(2013)
C_WHO
Download these technical notes directly from the website: These four-page illustrated notes, originally prepared in 2011 and updated in 2013, provide practical, evidence-based recommendations in responding to immediate and medium-term water, sanitation and hygiene
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needs of populations affected by emergencies.
The notes are relevant to a wide range or emergency situations, including both natural and conflict-induced disasters. They are suitable for field technicians, engineers and hygiene promotors, as well as staff from agency headquarters.
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A public health emergency operations centre (EOC) is a central location for coordinating operational information and resources for strategic management of pugencies and events. EOCs provide communication and information tools and services blic health emer-
and a management system during a response
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to an emergency or event. This report lays out components and characteristics of an emergency operations plan, providing a suggested structure for plans and procedures. The planning process, and that of coducting a hazard analysis or needs assessment, are also discussed as key steps
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