This topic last updated: Apr 28, 2020.
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Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them.
Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed.
Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species.
Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition.
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Infection 2023 Oct;51(5):1399-1406. doi: 10.1007/s15010-023-01999-9. Epub 2023 Feb 20.
The results indicate a significantly higher rate of infections with S. mansoni in street children compared with orphans. This might be explained by the lack of access to adequate sanitation for street children ...as well as regular contact with the water of Lake Victoria. However, we did not find similar results concerning infection rates with protozoa. The study results show overall inadequate living conditions in this study population, which could be addressed by public health interventions.
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Cette affiche sur Ebola ainsi que ces 20 messages étaient developpés par les personnes qui ont travaillé avec les enfants a Sierra Leone pendant la crise d´Ebola en 2014. CfH a 100 autres messages pour apprentissage et partage par les enfants a travers 10 sujets de Santé
Le document fournit des messages éducatifs et des conseils pratiques pour prévenir et gérer la diarrhée, en particulier chez les enfants. Il met l'accent sur les pratiques d'hygiène telles que le lavage des mains adéquat, l'utilisation de latrines et la manipulation sûre des aliments. Il soul...igne également l'importance de l'allaitement maternel, d'une alimentation équilibrée, de la vaccination et de l'utilisation de solutions de réhydratation orale (SRO) et de zinc pour traiter la déshydratation causée par la diarrhée. Développé en collaboration avec les programmes de Save the Children en République démocratique du Congo, le matériel intègre l'éducation à la santé dans les écoles et les communautés, en encourageant les enfants à agir comme agents de changement pour promouvoir les pratiques d'hygiène et de santé.
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Mosala na biso eza po na matangisi ya bokólogónu ya mwana. Likasa oyo likolo ya Ebola na mayebisi 20 esalamaki na bato oyo ba salaki na bana na ekolo ya Sierra Leone na tango ya kokoso ya Ebola na 2014. CfH azali na mayebisi mosusu 100 po na kotanga pe
pona bana bapanza likolo ya mayebisi 10 po n...a bokólóngónu
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Storybook which is about children's well being and resilience
The 'Zzippi Drinks Blood' booklet is designed to be used as a teaching aid by health educators. It can be used to support malaria prevention teaching sessions and displayed on walls to help children remember the key messages. The illustrations can also be copied and used to create flashcards or a fl...ipbook, facilitating interactive learning. Educators are encouraged to adapt the content to suit their local context, and to consult experts to ensure accuracy.
Accessed on 14/07/2025.
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This document outlines key health messages for children and their caregivers, with a focus on the prevention and early treatment of common illnesses. Topics covered include malaria, diarrhoea, malnutrition, respiratory infections, intestinal worms, HIV/AIDS and accident prevention. The importance of... insecticide-treated nets, oral rehydration salts (ORS), breastfeeding, immunisation, hygiene, access to clean water, deworming and emotional care for child development is also emphasised. The practical advice provided helps families to create safer and healthier environments, and to recognise when medical help is needed.
Accessed on 15/07/2025.
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Children without access to safe water are more likely to die in infancy -- and throughout childhood -- from diseases caused by
water-borne bacteria, to which their small bodies are more vulnerable.
Chapter 21 from "Where there is no doctor"
This article identifies the three core defining characteristics of healing environments for children and young people who have been exposed to chronic adversity and trauma. A large body of evidence highlights the pervasive and devastating developmental impacts of such exposure but there is also emer...ging evidence about the elements of living and learning environments that foster recovery and resilience. The Three Pillars framework has been developed to inform and empower those who live with or work with these young people but who are not necessarily engaged in formal therapy.
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The Global Health eLearning Center offers courses aimed at increasing knowledge in a variety of global health technical areas. A complete listing of courses is below. Individual courses are also part of certificate programs, listed to the left, as well as on the Certificate Program page. Courses tha...t have been translated and can be found on the Translation page.
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Helping Children Who are Deaf Book. Appendix A.
This report aims to provide Syrian children with a platform to make their voices heard. Their stories highlight the urgent need to address the psychosocial well-being of children affected by the Syrian civil war, and in all emergencies
A handbook on child-responsive urban planning