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5
1
- The goal of diagnostic testing for Ebola and Marburg virus diseases is to identify cases to provide timely and appropriate care and to stop disease transmission.
- All individuals meeting the case definition for Ebola or Marburg
...
virus diseases should be tested.
- The recommended sample type for testing for orthoebolaviruses and orthomarburgviruses is whole blood or plasma for living patients, and oral swab for deceased individuals.
- Laboratory confirmation of Orthoebolavirus and Orthomarburgvirus infections and further species identification should be done using nucleic acid amplification testing (NAAT).
- If a suspected case tests negative (living patient) and the blood was drawn less than 72 hours after symptom onset, a second test should be performed with blood drawn more than 72 hours after symptom onset.
- All manipulations in laboratory settings of samples originating from suspected, probable or confirmed cases of Ebola and Marburg virus diseases should be conducted with appropriate biosafety measures according to a risk-based approach.
- Whole or partial genome sequencing can be used to characterize viruses and complement epidemiologic investigations.
- Member States are strongly encouraged to share genetic sequence data (GSD) in publicly accessible databases.
- Member States are required to immediately notify the World Health Organization (WHO) under the International Health Regulations (IHR) 2005 of positive laboratory results.
more
On 4 September 2025, the Ministry of Health of the Democratic Republic of the Congo (DRC) declared an outbreak of Ebola Virus Disease (EVD) in Kasai Province, following confirmation of Zaire ebolavirus by the National Institute of Biomedical Researc
...
h (INRB) in Bulape and Mweka Health Zones. As of 19 September, there have been 48 total cases (38 confirmed, 10 probable) with 31 deaths (21 confirmed, 10 probable) and a CFR of 64.5%. Among laboratory confirmed cases, 16 deaths were recorded (CFR: 45.7%). Four deaths occurred among health workers, underscoring the risk of nosocomial transmission. Most cases (39.7%) are among adults aged 20 years and above, in a densely populated, remote, and under-resourced area.
The outbreak is driven by multiple risk factors, including transmission in health facilities with limited infection prevention and control (IPC) measures and personal protective equipment (PPE), incomplete contact tracing, delayed detection, and unsafe burial practices. High population mobility between Bulape and Tshikapa, reliance on traditional healers, and the concurrent mpox outbreak are further straining the fragile health system and increasing the risk of geographic spread.
more
L’épidémie de maladie à virus Ebola représente l’une des menaces sanitaires les plus graves pour la santé publique mondiale, en raison de sa létalité élevée, de sa propagation rapide et de ses conséquences sociales, économiques et sé
...
curitaires. L’expérience des 16 précédentes flambées en République Démocratique du Congo et dans d’autres pays d’Afrique de l’Ouest a montré que la préparation et la réponse rapide sont essentielles pour contenir efficacement la maladie et sauver des vies.
more
Between April 2018 and November 2020, the Democratic Republic of Congo (DRC) experienced its 11th Ebola virus disease (EVD) outbreak. Tanzania’s cross-border interactions with DRC through regular visitors, traders, and refugees are of concern, giv
...
en the potential for further spread to neighboring countries. This study aimed to estimate the risk of introducing EVD to Tanzania from DRC. National data for flights, boats, and car transport schedules from DRC to Tanzania covering the period of May 2018 to June 2019 were analyzed to describe population movement via land, port, and air travel and coupled with available surveillance data to model the risk of EVD entry. The land border crossing was considered the most frequently used means of travel and the most likely pathway of introducing EVD from DRC to Tanzania. High probabilities of introducing EVD from DRC to Tanzania through the assessed pathways were associated with the viability of the pathogen and low detection capacity at the ports of entry. This study provides important information regarding the elements contributing to the risk associated with the introduction of EBV in Tanzania. It also indicates that infected humans arriving via land are the most likely pathway of EBV entry, and therefore, mitigation strategies including land border surveillance should be strengthened.
more
This review article examines 42 years of Ebola virus disease (EVD) outbreaks in Sub-Saharan Africa, from 1976 to 2019. The authors analyze the epidemiology, geographical distribution, mortality rates, and response strategies associated with 34 Ebola
...
outbreaks across 11 African countries. The review identifies key challenges in controlling Ebola, including weak health systems, limited surveillance and laboratory capacity, sociocultural practices, environmental changes, and community mistrust. It also discusses advances in diagnostics, treatments, and vaccines, and emphasizes the importance of a One Health approach, community engagement, effective communication, and stronger healthcare systems to improve preparedness, prevention, and response to future Ebola outbreaks.
more
Le guide du communicateur dans le contexte de l’épidémie de la maladie à virus Ebola est un outil de travail développé par le pilier Communication de Risque et Engagement Communautaire (CREC), du Système Continental de Gestion des Incident
...
s (IMST), en réponse à la seizième épidémie de la maladie à virus Ebola déclarée le 4 septembre 2025.
more
The communicator's guide in the context of the Ebola virus disease epidemic is a
working tool developed by the Risk Communication and Community Engagement
(RCCE) pillar of the Continental Incident Management System (CIMS), in response to
the s
...
ixteenth Ebola virus disease outbreak declared on September 4, 2025.
more
Healthcare waste management in the context of Ebola Virus Disease (EVD) presentation is part of the EVD IPC training material to HC IIs and pharmacies. All waste in holding areas should be considered infectious. Staff should always wear appropriate
...
personal protective equipment (PPE) when handling and treating hazardous waste.
more
The Ministry of Health of Saudi Arabia has developed the guidelines to meet the urgent need for up -to-date information and evidence-based recommendations
This document provides guidelines on the establisment of early surveillance actions to be carried out in countries where no case of Ebola virus disease has been reported.
An alert system should be in place at the following sites: major land border
...
crossing with already affected countries; capital cities, including at airports, seaports, and health-care facilities, especially in major hospitals.
The alert system (staff trained in case definitions and able to detect signs and symptoms of disease) should report sick persons coming from country that has reported cases of Ebola virus disease (EVD) and possibly meeting the definition of a case under investigation
more
WHO Interim Guidance for Internation al Meetings Attended by Individuals f rom Ebola Virus Disease - affected countries
World Health Organization
(2014)
This interim guidance is aimed at assisting organizers of international meetings attended by individuals from EVD-affected countries and individuals with a travel history to EVD-affected countries within the previous 3 weeks.
The first part is intended for organizers of international meetings, to
...
safely plan and conduct these events. The second part is addressed to public health authorities directly involved in supporting such international meetings.
more
