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Cardiac arrhythmias in low- and middle-income countries

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Many low- and middle-income countries (LMICs) are undergoing an epidemiological transition. With an improvement in socioeconomic conditions and an aging population, cardiovascular diseases (CVDs), like cardiac arrhythmias, are expected to increase in these countries. However, there are limited studi... more
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An overview of heart failure in low- and middle-income countries

Agbor, V.N.; Ntusi, N.A.B.; Noubiap, J.J. Cardiovascular Diagnosis and Therapy (2020) CC
Heart failure (HF) is a global public health concern with disproportionate socioeconomic, morbidity and mortality burden on low- and middle-income countries (LMICs). This review summarises contemporary data on the demographic and clinical characteristics, aetiologies, treatment, economic burden and ... more
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Management and Control of Viral Haemorrhagic Fevers and other highly contagious viral pathogens

European Network for Diagnostics of Imported Viral Diseases (2001) C1
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SARS-CoV-2 molecular assay evaluation: results
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Foundation for Innovative and New Diagnostics (2020) C2
FIND conducted independent evaluations at the University Hospitals of Geneva (HUG), to verify the limit of detection (LOD) and the clinical performance (as reported by the manufacturers) of the following molecular test kits. The LOD analysis was performed using cultured viral stocks from a clinical ... more
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Rapid Extraction Method of Mycobacterium ulcerans DNA from Clinical Samples of Suspected Buruli Ulcer Patients

Frimpong, M.; H. Senanu Ahor; S.A. Sakyi, et al. (2019) CC
Diagnostics 2019, 9(4), 204; https://doi.org/10.3390/diagnostics9040204
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cobas®SARS-CoV-2

Cobas (2020) C1
Qualitative assay for use on the cobas®6800/8800 Systems. For in vitro diagnostic use
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Tropical Medicine Point-of-Care Testing. Update 2022
recommended

Cheesbrough, M. THT Books (2022) C1
To meet the need for laboratory diagnosis to be integrated in community care, the new 2022 Update describes point-of-care tests that can be performed both in district laboratories and peripheral healthcare facilities by non-specialist staff. Also included are recently developed self-tests.
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Guidelines for Management of Malaria in Zimbabwe

Ministry of Health and Child Welfare, Zimbabwe (2009) C1
DIAGNOSIS, MANAGEMENT OF UNCOMPLICATED AND SEVERE MALARIA
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Métodos de diagnóstico para a doença de Chagas: uma atualização

Ferreira Alves, D.; et al. (2018) CC
Diagnostic methods of Chagas disease: an update. RBAC. 2018;50(4):330-3
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Botswana: National Health Quality Standards (Standards & Guidelines for Hospitals, Volume 2)

Ministry of Health, Gabarone, Botswana (2013) C2
Diagnostic, Care and Treatment Support Services. Volume 2: Improving Quality & Safety of Health Services. National Health Quality Standards. Standards and Guidelines for Hospital Standards. Volume 2
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Collection of Dried Blood Spots (DBS) from Infants for PCR Testing

Centers for Disease Control and Prevention (CDC) (2018) C1
This clinical job aid provides health care workers with information on how to collect specimens for early infant diagnosis on dried blood spots, as well as drying and packaging for transport.
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BMJ's Coronavirus (covid-19) Hub

British Medical Journal (2020) CC
BMJ has created a free resource on SARS-CoV-2 and covid-19 to inform diagnosis and treatment, and to promote the wellbeing and safety of staff and patients during this extremely stressful and challenging period. BMJ’s dedicated covid-19 hub not only draws on the latest peer reviewed research, n... more
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Predictive values of Ebola RDTs and implications for decision-makers

World Health Organization (WHO) (2015) C_WHO
Annex to Selection and use of Ebola in vitro diagnostic assays
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World Atlas of BCG Policies and Practices

Alice Zwerling, Marcel Behr, Aman Verma, et al. McGill University & McGill University Health Center Montreal; Public Health Agency of Canada (2015)
This interactive website provides detailed information on current and past BCG policies and practices for over 180 countries. The Atlas is designed to be a useful resource for clinicians, policymakers and researchers alike, providing information that may be helpful for better interpretation of TB di... more
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Symptom-based screening tool for asthma syndrome among young children in Uganda

Nantanda, R.; Siersma, V.; Ndeezi, G. et al. npj Primary Care Respiratory Medicine (2020) CC
Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu... more
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Cognitive profiles of Post-traumatic Stress Disorder and depression in children and adolescents

Barrera-Valenciaa, M., Calderón-Delgado, L., Trejos-Castillo, E. & O’Boyle, M. International Journal of Clinical and Health Psychology (2017) CC
Several diagnostic criteria of Post-traumatic Stress Disorder (PTSD) are remarkably similar to symptoms reported by individuals with depression, particularly as they manifest as cognitive processing deficits in children. Because of this overlap in profile and the high rate of comorbidity of PTSD and... more
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MSF Medical Guidelines App

Medécins sans Frontières (2017) C2
This diagnostic and treatment manual is designed for use by medical professionals involved in cura- tive care at the dispensary and hospital levels. We have tried to respond in the simplest and most practical way possible to the questions and problems faced by field medical staff... more
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Guidelines on hepatitis B and C testing
recommended

World Health Organization (WHO) (2017) C_WHO
Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to recei... more