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Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
This document is itended as a quick guide of healtcare workers involved in clincial management
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
...
al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
more
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects
but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low
antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is
highly dep
...
endent on the availability and accessibility of patient-centred care, which enables women
and their families to take informed decisions about their health and the health of their infant. For
this reason, it is recommended to have a patient-centred approach when implementing PMTCT.
PMTCT success is also linked to the partners’ involvement, as well as to community acceptance
of HIV.
more
Journal of Adolescent Health 2022 1-16
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health
Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for
HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact
...
urers long-term arrangements
(LTAs) to supply WHO prequalified product
more
HIV/AIDS Hope Initiative
This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi
...
ng on their strengths, FBOs can potentially serve as useful platforms for engaging men and other priority populations, promoting greater demand, uptake, and retention in care.
more
The Global Aids Strategy 2026-2031
recommended
United- Towards Ending AIDS. The Global AIDS Strategy 2026-2031 focuses global efforts for the future of the AIDS response to end AIDS as a public health threat by 2030 and sustain the HIV response after 2030. This is a strategy uniting the world.
The Strategy will shape the June 2026 United Natio
...
ns General Assembly High-Level Meeting on Ending AIDS and its political declaration. It provides all actors in the field with guidance to overcome the challenges and to ensure effective country-led AIDS responses. The Global AIDS Strategy 2026-2031 includes new global targets for 2030 and resource needs estimates.
more
United- Towards Ending AIDS. The Global AIDS Strategy 2026-2031 focuses global efforts for the future of the AIDS response to end AIDS as a public health threat by 2030 and sustain the HIV response after 2030. This is a strategy uniting the world.
The Strategy will shape the June 2026 United Natio
...
ns General Assembly High-Level Meeting on Ending AIDS and its political declaration. It provides all actors in the field with guidance to overcome the challenges and to ensure effective country-led AIDS responses. The Global AIDS Strategy 2026-2031 includes new global targets for 2030 and resource needs estimates.
more
The document “Public Health Surveillance for Cholera – Guidance Document (2024)” provides practical recommendations for countries on how to design, implement, and strengthen cholera surveillance systems. Developed by the Global Task Force on Cholera Control (GTFCC), it outlines the minimum req
...
uirements for detecting, confirming, reporting, and monitoring cholera cases and outbreaks.
The guidance explains the core functions of cholera surveillance, including case detection, laboratory testing (such as RDTs, culture, and PCR), routine data collection, outbreak notification, case and field investigation, data analysis, and performance monitoring. It also describes how surveillance strategies should be adapted depending on whether a country is experiencing no outbreak, clustered transmission, or community transmission.
Overall, the document aims to help countries establish adaptive, fit-for-purpose surveillance systems that enable early outbreak detection, guide timely response measures, and support long-term cholera control and elimination efforts.
more
The document “Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa” outlines a coordinated strategy developed by Africa CDC to improve public health surveillance and collaboration across national borders in Africa. It addresses the challenge that infe
...
ctious diseases often spread across borders due to population movement, trade, and migration, while surveillance systems and data-sharing mechanisms frequently remain nationally focused and fragmented.
The framework proposes strengthening regional coordination, harmonizing surveillance systems, enhancing information sharing between countries, and building laboratory and workforce capacity. It also emphasizes timely detection of cross-border health threats, joint outbreak investigations, and improved communication among Member States. Overall, the document aims to enhance preparedness, early warning systems, and collective response to public health threats across the African continent.
more
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
more
Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp
...
onse to emergencies. Each module aims to provide updated operational guidance for EWAR practices, which may be more easily understood and applied during emergencies. Through its application, this operational guidance aims to contribute to:
- earlier detection of acute public health events
- earlier and more effective response
- reduced impact of emergencies on health
- increased trust of the population in the (public) health system
- fulfilling our collective commitments to the International Health Regulations (IHR,
2005).
This guidance was developed jointly by 69 experts from more than 20 organizations from global level to country level.
more
This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
...
ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
more
The Health Emergency and Disaster Risk Management
Chan E.Y.Y., Huang Z., Hung K.K.C. et al
United Nations Office for Disaster Risk Reduction UNDRR
(2022)
CC
An emerging framework for achieving synergies among the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. This paper discusses the potential of the Health Emergency and Disaster Risk Management (Health-EDRM) Framework in promoting syne
...
rgies in pursing risk- resilient sustainable development pathways via conceptual analysis of the key roles of health and Health-EDRM in the major international risk-resilient and sustainable development agendas of the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. It first analyses the Health-EDRM Framework, which is a comprehensive, systematic, cross-sectoral, and interdisciplinary endeavour of the World Health Organization and its health and non- health partners. The four key international risk-resilient and sustainable development agendas are then analysed in detail to explore how they can be interlinked and synergised under the Health-EDRM Framework.
more
The Private Sector Engagement Strategy on HIV, STIs and TB is a is a guide that is both comprehensive
and focused, and it is to be used by businesses and corporations to actively participate in the HIV, STIs
and TB and Noncommunicable diseases (NCDs) response. The goal of this strategy is to devel
...
op a
culture in the workplace that actively promotes HIV, STIs and TB prevention, awareness, and support for
employees impacted by HIV, STIs and TB. The strategy incorporates several essential components, such
as those pertaining to prevention and education, accessibility to testing and treatment, reduction of stigma,
community participation, strategic alliances, employee empowerment and wellness, and data-driven
decision-making
more
