Psychiatry and Pediatrics
Chapter I.5
Infant Psychiatry
Chapter B.1
Early Maltreatment and exposure to violence
PLOS ONE | https://doi.org/10.1371/journal.pone.0185526 September 28, 2017
Global Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisboa, Portugal
Other
Chapter H.4
2015 edition
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit...h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
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Reporting period January 2015 – December 2015
Bucharest, April 2016
Research Article
BMC Infectious Diseases 2012, 12:262; doi:10.1186/1471-2334-12-262
A global Review of evidence and practice
Technical Brief
Damon Barrett, Gonçalo Figueiredo Augusto, Martiani Oktavia, Jeanette Olsson, Mira Schneiders and Kate Welch provided background papers and literature reviews which informed this technical series.
This booklet provides policymakers, planners, and other interested parties with insight into the current state of the Rwandan health sector. These statistics provide a basis for policies, strategies, and planned interventions to ensure they are responsive to the needs of the health sector and, cruci...ally, are focused on addressing current priorities that aim to improve the health of the Rwandan population.
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Recommendations for a public health approach
HIV/AIDS Programme
Эта глава начинается с обзора ключевых принципов развития, или тем, включая такие , как: природа или воспитание, продолжительность стадий развития и их эластичност..., критические и чувствительные периоды, а также роль культуры и контекста. После этой краткой вступительной главы будут рассмотрены зависящие от возраста этапы когнитивного, лингвистического социально-эмоционального и поведенческого развития от младенческого возраста, и до подросткового. Несмотря на то, что понимание этапов нормального физического развития также важно, эти вопросы обычно хорошо освещаются в медицинских публикациях и в данной главе не освещаются.
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The Ghanaian Cabinet approved the antimicrobial resistance (AMR)Policy and Implementation plan(hereafter referred to as the national action plan or NAP)in December 2017, whilst the country case study was in progress. This has set in motion the implementation phase for Ghana, which is a long awaited... event since the drafting of the Policy started in 2011. This case study, whilst limited in its ability to interact with all stakeholders, has identified entrypoints within the operational divisions of Ghana Health Services,as potential areas where the AMR policy platform may seek to embed AMR activities. Much work has already been done within Ghana to identify the key entrypoints within the various ministries and government agencieswhere AMR can be incorporated. These stakeholders already form part of the AMR Policy Platform which is the governance structure for AMR and have been participating actively in the development of the AMR Policy and NAP activities formulation.
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Developmental disorders
Chapter C.5
Research Article
PLOS ONE | DOI:10.1371/journal.pone.0169530 February 16, 2017