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Considerations for introducing new antiretroviral drug formulations for children

World Health Organization WHO (2020) CC

Policy brief. July 2020

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Meningitis

World Health Organization WHO (2025) C_WHO

1 April 2025. Key Facts

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Tanzania: CUE CARDS Provider Initiated HIV Testing and Counselling (PITC)

Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania (2009) C1

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Interim list of WHO medical devices for Ebola care - medical devices (not including personal protective equipment)

World Health Organization (2014)

Version 21 November 2014

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Managing Yellow fever epidemics

World Health Organization WHO (2019) C_WHO

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Eliminate Yellow fever Epidemics (EYE): a global strategy, 2017-2026

World Health Organization WHO (2018) C_WHO

The EYE strategy is a comprehensive and long-term strategy built on lessons learned that aims at ending yellow fever epidemics by 2026, and consists of three strategic objectives: protect at-risk populations; prevent international spread; and contain outbreaks rapidly.

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Keeping the vector out: housing improvements for vector control and sustainable development

Kraef, C.; Röbbel, N. World Health Organization WHO (2017) C_WHO

Vector-borne diseases are responsible for 17% of the global burden of communicable diseases and more than 500 000 deaths annually. The ambitious global targets for the control of vector-borne diseases come in the context of the (re-)emergence of diseases, increasing resistances to insecticides and u... more

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Preventing and managing COVID-19 across long-term care services (Arab Version)

World Health Organization WHO (2020) C_WHO

Policy brief, 24 July 2020 The COVID-19 pandemic has affected older people disproportionately, especially those living in long-term care facilities. In many countries, evidence shows that more than 40% of COVID-19 related deaths have been linked to long-term care facilities, with figures being as h... more

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Rwanda: MEDICAL WASTE MANAGEMENT PLAN (MWMP)

Ministry of Health, Rwanda (2017) C2

Prepared for the Stunting Prevention and Reduction Project - The project Medical Waste Management Plan’s (MWMP) overall objective is to prevent and/or mitigate the negative effects of increased generation of medical waste on human health and the environment. The plan proposes measures to prevent t... more

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COVID-19 Strategic Preparedness and Response Plan (SPRP 2021)
recommended

World Health Organization WHO (2021) C_WHO

1 February 2021 to 31 January 2022

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Kenya Framework for Elimination of Mother-To-Child Transmission of HIV and Syphilis 2016-2021

Kenya Ministry of Health, National AIDS and STI Control Program (2021) C1

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Lesotho: EXPANDED PROGRAMME ON IMMUNISATION COMPREHENSIVE MULT-YEAR PLAN (2012-2016)

Government of Lesotho, World Health Organization (WHO) & United Nations Children's Fund (UNICEF) (2012) C_WHO

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In the wake of the pandemic. Preparing for Long COVID-19

Rajan, S.; et al. World Health Organization WHO, Regional Office of Europe (2021) C_WHO

Policy Brief. Our understanding of how to diagnose and manage Long COVID is still evolving but the condition can be very debilitating. It is associated with a range of overlapping symptoms including generalized chest and muscle pain, fatigue, shortness of breath, and cognitive dysfunction, and the ... more

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Report of Access to COVID-19 Tools Accelerator Facilitation Council Working Group on Diagnostics and Therapeutics

World Health Organization WHO (2022) C_WHO

This report’s central premise is that diagnostics and therapeutics, and associated test to treat strategies, are fundamental components of the pandemic response, both for COVID-19 and for future health threats. Two years into the COVID-19 pandemic, this report reflects on the main challenges and k... more

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Fair allocation mechanism for COVID-19 vaccines through the COVAX Facility

World Health Organization WHO (2020) C_WHO

9 September 2020 In a snapshot, fair allocation of vaccines will occur in the following way: An initial proportional allocation of doses to countries until all countries reach enough quantities to cover 20% of their population This document is also available in Arabic | Chinese | French | R... more

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WHO Guidelines for the Treatment of Neisseria gonorrhoeae
recommended

Santesso, N.; J. Wasserheit, H. Schünemann, et cl. World Health Organization (WHO) (2016) C_WHO

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Ebola virus disease preparedness strengthening team Ghana country visit 10–15 Novmeber 2014

World Health Organization (2014)

The preparedness strengthening team deployed to Ghana focused on specific objectives in order to assist the country in becoming as operationally prepared as possible to detect, investigate and report potential EVD cases effectively and safely and to mount an effective response to prevent a larger o... more