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Lineamientos técnicos para la atención de personas con tuberculosis presuntiva y seguimiento de casos diagnosticados, en el marco de la pandemia por COVID-19
Dr. Francisco José Alabí Montoya, Dr. Carlos Gabriel Alvarenga Cardoza, Dra. Karla Marina Díaz de Naves
Ministerio de Salud El Salvador
(2021)
C1
Clinical guidelines for the care of persons with suspected tuberculosis and and follow-up of diagnosed cases, in the context of the COVID-19 pandemic
The South African Department of Health reports a decline in cholera cases, with only one confirmed case out of 28 suspected cases in the last 10 da
...
ys as of July 5, 2023. However, authorities urge continued vigilance, emphasizing hygiene, especially during mass gatherings.
Since February 2023, South Africa has recorded 1,073 suspected cholera cases, with 198 confirmed cases across five provinces. Gauteng Province is the most affected, with 176 cases, primarily in Hammanskraal, Tshwane. Other affected provinces include Free State, North West, Limpopo, and Mpumalanga.
The outbreak has resulted in 47 deaths, with four new suspected deaths reported in the Free State. The majority of confirmed cases are in individuals aged 41-50 years, and 52% of cases are female.
The health department continues preventive efforts through health education and targeted case-finding. Authorities also stress the importance of clean water and hygiene compliance in initiation schools to prevent further outbreaks.
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Prevention and Control of Covid-19 Transmission: Isolation and follow-up of suspected and/or confirmed cases and close contact tracing strategy
The report provides an epidemiological update on cholera outbreaks in Haiti as of January 17, 2023. Since the first confirmed cases in October 2022, Haiti has reported 24,232 suspected
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cases, including 1,742 confirmed cases and 483 deaths. The most affected areas are in the Ouest Department, particularly Port-au-Prince. Children aged 1 to 4 years are the most affected group. The ongoing humanitarian crisis, security issues, and limited access to healthcare have worsened the outbreak, hindering epidemiological surveillance and case reporting. The PAHO/WHO is working with Haitian authorities to respond to the outbreak and mitigate its spread.
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Between epidemiological weeks (EW) 1 and 22 of 2024, a total of 9,541,015 suspected cases of dengue were reported, resulting in a cumulative incidence of 1,011 per 100,000 population. This represent
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s an increase of 230% compared to the same period in 2023 and 421% compared to the average of the last 5 years. Figure 1 shows the trend of suspected dengue cases as of EW 22.
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- The goal of diagnostic testing for Ebola and Marburg virus diseases is to identify cases to provide timely and appropriate care and to stop disease transmission.
- All individuals meeting the case definition for Ebola or Marburg virus diseases
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should be tested.
- The recommended sample type for testing for orthoebolaviruses and orthomarburgviruses is whole blood or plasma for living patients, and oral swab for deceased individuals.
- Laboratory confirmation of Orthoebolavirus and Orthomarburgvirus infections and further species identification should be done using nucleic acid amplification testing (NAAT).
- If a suspected case tests negative (living patient) and the blood was drawn less than 72 hours after symptom onset, a second test should be performed with blood drawn more than 72 hours after symptom onset.
- All manipulations in laboratory settings of samples originating from suspected, probable or confirmed cases of Ebola and Marburg virus diseases should be conducted with appropriate biosafety measures according to a risk-based approach.
- Whole or partial genome sequencing can be used to characterize viruses and complement epidemiologic investigations.
- Member States are strongly encouraged to share genetic sequence data (GSD) in publicly accessible databases.
- Member States are required to immediately notify the World Health Organization (WHO) under the International Health Regulations (IHR) 2005 of positive laboratory results.
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SITUATION OVERVIEW as of 30 Jan.
- 688 000 refugees into Bangladesh (of which 585 000 in Kutupalong and Bulukhali camps)
- over 5000 clinically suspected Diphtheria cases and 37 deaths (reported
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in refugee camps)
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Integrated Response Plan: Yemen Cholera Outbreak
recommended
The plan outlines emergency health, WASH and communications interventions to contain and prevent further spread of the outbreak in the 227 high risk districts, where suspected cholera cases were rep
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orted during the period October 2016 to May 2017. Health and WASH clusters will continually identify priority districts from at
high risk districts, by considering the number of caseload and attack rate. As of 15 May, 30 priority high risk districts (10 Governorates) that report over 100 or more suspected cholera cases have been identified.
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The document presents Cameroon's National Response Plan for the 2018 cholera outbreak, covering August to October 2018. It highlights the epidemiological situation, with outbreaks reported in the North and Central regions and a total of 109 suspected
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cases and 9 deaths by July 2018. The plan outlines strategies for controlling the epidemic, including epidemiological surveillance, improved access to clean water, sanitation, mass vaccination, community awareness campaigns, and hospital and community-based treatment.
The response is coordinated by the Ministry of Public Health, WHO, and various partners, focusing on early detection, rapid response, and multi-sectoral collaboration. Challenges include poor sanitation, limited healthcare infrastructure, and cross-border disease transmission risks. The plan emphasizes resource mobilization, monitoring, and evaluation to contain the outbreak and prevent future cases.
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On 17 October 2017, the Ugandan Ministry of Health notified WHO of a confirmed Marburg outbreak of Marburg Virus disease (MVD) in Kween district, Eastern Uganda. The outbreak was officially declared by the Ministry of health on 19 October 2017.
As of 7 November, four
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cases of MVD have been reported- two confirmed (dead), one probable (dead) and one suspected. Other patients, previously reported as suspected cases, have since tested negative for the virus.
WHO has been implementing the Emergency Response Plan since 20 October 2017 when the Ministry of Health officially declared the outbreak. The Emergency Response Plan was developed on several assumptions which may now need to be revised.
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For health professionals located outside affected regions, online learning courses from BMJ Learning [http://learning.bmj.com/learning/module-intro/.html?moduleId=10058695] offer guidance on how to recognise who is most at risk and how to manage suspected
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cases of Ebola in primary care.
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Just 15 weeks into 2019, more measles outbreaks have been declared in South Sudan than occurred in all of 2018. As of Wednesday, 10 April, there had been 11 active outbreaks and four deaths had been confirmed. Another two deaths are suspected
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cases of measles. Earlier this year a campaign to vaccinate children across South Sudan was delayed due to a shortage of vaccines and funding
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A new publication - Waste Management during the COVID-19 Pandemic: from response to recovery - reviews current practices for managing waste from healthcare facilities, households and quarantine locations accommodating people with confirmed or suspected
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cases of COVID-19. Jointly produced by UNEP, the Institute for Global Environmental Strategies and the International Environmental Technology Centre, the report considers various approaches, identifies best practices and technologies, and provides recommendations for policy-makers and practitioners to improve waste management, over the long term.
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7 June 2022. To treat complications associated with measles: severe complications with module 1 (50 cases) and mild complications with module 8 (20 cases).
The new measles kit 2021 is designed to p
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repare for and support the treatment of non-severe and severe measles cases during outbreaks. The kit provides the essential medicines, supplies and equipment for the management of clinical suspected and severe cases.
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The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challeng
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e for health professionals. It requires early recognition of signs and symptoms, which are often nonspecific, and it can mimic other acute febrile syndromes. Early detection of suspected or confirmed cases, monitoring of vital signs, life support measures, and treatment of acute kidney failure continue to be the recommended strategies for case management. This report is the result of discussions among experienced specialists in the Americas on the clinical management of yellow fever patients, especially during outbreaks and epidemics, in the context of current medical and scientific evidence and taking into account the technical guidelines already available in the countries of the Region. It includes flowcharts for initially addressing patients with clinical suspicion of yellow fever and proposes a minimum package of laboratory tests that may be useful in contexts where resources are limited. In addition, it considers aspects of health system organization for dealing with yellow fever outbreaks and epidemics.
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The report provides an update on the cholera outbreak in Haiti as of January and February 2024. A total of 79,411 suspected cases have been reported, with 4,608 confirmed
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cases and 1,172 deaths across all 10 departments. The most affected regions include Ouest, Centre, Artibonite, and Nord, with children aged 1-9 being the most impacted. Despite a recent decline in reported cases, underreporting due to security issues remains a concern. Response efforts include coordination meetings, epidemiological surveillance, case management, WASH interventions, vaccination campaigns, and community engagement. However, logistical challenges, insecurity, and funding shortages are hindering effective response efforts.
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This document summarizes Haiti's cholera situation as of November 16, 2016. Between January and October 2016, Haiti reported 35,203 new suspected cholera cases (32% increase from 2015) and 369 death
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s (56% increase). After Hurricane Matthew, cases rose dramatically, with 52% of new cases concentrated in Grand'Anse and South departments. Since the 2010 outbreak began, Haiti had experienced 797,000 total cases and 9,353 deaths. The report identifies key factors contributing to cholera persistence: weak water and sanitation infrastructure, limited healthcare access, underfunding, population density, and mobility. Despite concerning trends, humanitarian partners were cautiously optimistic as a feared nationwide outbreak following Hurricane Matthew had not materialized, and a vaccination campaign was underway. However, the cholera response was significantly underfunded, with only 42% of requested funds received.
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This document is a situation report (#6) from October 2, 2017, describing the cholera outbreak in Yemen. By October 1, 2017, there were 777,229 suspected cholera cases and 2,134 deaths across 22 of
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Yemen's 23 governorates. The response involves WASH partners providing hygiene supplies and water treatment, health cluster partners operating treatment centers, and communication campaigns reaching over 16 million people. Major challenges include limited supplies, security risks hindering access to affected communities, a weakened health system with over 55% of facilities closed or partially functional, and difficulties importing medicines and medical supplies. Children under 18 represent 60% of cases, while people over 60 report the highest death rates.
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Plos Current Outbreaks
An outbreak of Lassa Fever (LF) reported and confirmed in Ondo state, Southwest Nigeria in January 2016 was investigated. This paper provides the epidemiology of the LF and lessons learnt from the investigation of the outbreak.
Results: We identified 90 ... suspected LF cases of which 19 were confirmed by the laboratory. More than half (52.6%) of the confirmed cases were females with majority (73.7%) in the age group ≥ 15 years. The Case Fatality Rate (CFR) of 63.2% among the laboratory-confirmed positive cases where 9 of 19 cases died, was significantly higher compared to the laboratory confirmed negative cases where 6 of the 65 cases died ( CFR; 8.5%) p ≤ 0.05. Two hundred and eighty-seven contacts of the confirmed cases were identified, out of which 267(93.0%) completed the follow-up without developing any symptoms and 2 (0.7%) developed symptoms consistent with LF and were confirmed by the laboratory. More than half of the contacts were females (64.5%) with most of them (89.2%) in the age group ≥ 25 years. more
Results: We identified 90 ... suspected LF cases of which 19 were confirmed by the laboratory. More than half (52.6%) of the confirmed cases were females with majority (73.7%) in the age group ≥ 15 years. The Case Fatality Rate (CFR) of 63.2% among the laboratory-confirmed positive cases where 9 of 19 cases died, was significantly higher compared to the laboratory confirmed negative cases where 6 of the 65 cases died ( CFR; 8.5%) p ≤ 0.05. Two hundred and eighty-seven contacts of the confirmed cases were identified, out of which 267(93.0%) completed the follow-up without developing any symptoms and 2 (0.7%) developed symptoms consistent with LF and were confirmed by the laboratory. More than half of the contacts were females (64.5%) with most of them (89.2%) in the age group ≥ 25 years. more
WHO invites Member States, health facilities and other entities to participate in the global effort to collect anonymized clinical data relating to suspected or confirmed cases of monkeypox and cont
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ribute data to the WHO Global Clinical Platform.
WHO has developed a clinical characterization case report forms (CRF) to standardize data collection of clinical features of monkeypox among outpatient and hospitalized cases.
For onboarding to the WHO Global Clinical Platform for monkeypox, please contact: monkeypox_clinicaldataplatform@who.int
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