All lyssaviruses have evolved closely with distinct natural reservoir hosts. The latter are animals species in which a pathogen of an infectious disease are maintained independently. For lyssaviruses, these are a wide range of mammalian species within the Carnivora and Chiroptera (bats) orders with ...a global distribution.
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In the Philippines, the month of March is celebrated as Rabies Awareness Month (RAM) every year as decreed by presidential executive order. A massive information campaign around rabies prevention/control is conducted, along with a free, mass dog vaccination campaign throughout the entire country.
Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi...ldren and impoverished communities being affected disproportionately.
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Overview
The aim of this guide is to support national immunization programme managers and others responsible for implementing human rabies vaccine programmes to:
inform policy discussions and operational planning for introducing or expanding rabies post-exposure prophylaxis (PEP) into a nationa...l immunization programme (e.g. through the national immunization programme, or other programmes); and
highlight considerations specific to rabies PEP for integration into existing systems, including for implementation, and monitoring and evaluation.
While the guide is mainly intended for programme managers and focuses on human vaccination, complementary animal health measures are highlighted where relevant given the zoonotic nature of rabies.
The guide was developed collaboratively with input from technical experts in rabies and immunization, vaccines and biologicals.
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Each year, rabies causes approximately 59,000 deaths worldwide. Despite evidence that control of dog rabies through animal vaccination programs and elimination of stray dogs can reduce the incidence of human rabies, dog rabies remains common in many countries and exposure to rabid dogs is still the ...cause of over 90% of human exposures to rabies and of 99% of human rabies deaths worldwide. CDC experts in the Poxvirus and Rabies Branch conduct an annual assessment of individual countries’ rabies status worldwide which considers the presence of wildlife rabies, canine rabies variant (dog rabies), and non-rabies lyssaviruses.
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These new guidelines should help medical and paramedical professionals to provide the state of art rabies prophylaxis to all animal bite victims in the government hospitals and prevent human rabies deaths in the state. The medical officers whenever in doubt are encouraged to contact the state nodal ...officer and seek further clarifications regarding PEP.
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Rabies is an infectious viral disease that is almost always fatal once clinical symptoms appear.
In most cases, the disease is transmitted to humans by the bite of a rabid dog, but infection can also spread through scratches or via saliva.
Rabies kills one person every 9 minutes and children aged ...5–14 years are frequent victims.
Yet rabies is 100% vaccine preventable. Vaccinating dogs is the most cost-effective way to prevent rabies in people.
Education about dog behaviour, immediate care measures after a bite, responsible dog ownership and bite prevention are essential components of rabies elimination.
WHO and partners aim to achieve zero human rabies deaths by 2030.
The time to act is now.
More information: http://www.who.int/rabies/en/
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Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ...and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
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Guide; revised 15 June 2010
For more than 100 years, the clearest route to elimination of dog-mediated rabies has been via mass vaccination of the animal hosts. It’s worked in plenty of countries. Still, in others, like India, which grapples with a third of the world’s rabies burden, large populations of free-roaming, hard...-to-track, often hard-to-reach dogs have made elimination an elusive goal.
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Classical rabies caused by RABV occurs worldwide besides some isolated countries and Western Europe that are regarded rabies free. Carnivores, especially of the canidae family represent the principal reservoir species and are responsible for the maintenance of the infectious cycle and hence for the ...presence of the disease (see Epidemiology of rabies). While wildlife rabies maintained by different reservoirs hosts predominantly occurs in the Northern hemisphere, canine rabies is by far more important for public health in the developing world.
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Rabies is a zoonotic, vaccine-preventable viral disease that causes damage to the brain and spinal
cord in infected animals and humans. A zoonotic disease is a disease that can be transmitted
between animals and humans. Rabies is nearly 100% fatal once symptoms appear.
As of 14 December 2021, a total of 19 laboratory-confirmed human rabies cases has been reported in South Africa for 2021. The cases are from Eastern Cape, KwaZuluNatal and Limpopo provinces. In addition, four probable rabies cases were reported from KwaZulu-Natal and the Eastern Cape provinces. A pr...obable case of rabies is defined as a person who has had a history of contact with a suspected or confirmed rabid animal and has developed an acute encephalitis with hyperactivity and paralytic signs and symptoms that progressed and resulted in death, usually by cardiac or respiratory failure, typically within ten days.
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WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies vaccines.
These vaccines must comply with WHO criteria for potency and innocuity following satisfactory ass...essment in humans during well-designed field trials
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Website last accessed on 08.06.2023
Rabies is a fatal viral disease, but is preventable in humans. The rabies virus is transmitted to humans through virus-laden saliva from a rabid animal, mostly dogs. The virus is shed in the saliva of an infected animal and can be introduced into another body through bites, scratches and any other ...wounds that transect the skin. Contact of the infected saliva with mucous membranes is also thought to be a possible route of infection, whereas contact of infected saliva with intact skin is not considered an exposure. Rabies is preventable through pre-exposure prophylaxis (PrEP) for individuals at high and continual risk, and post-exposure prophylaxis (PEP).
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Human rabies remains a significant public health problem in Africa with outbreaks reported in most countries. In Nigeria–the most populous country in Africa–rabies causes a significant public health burden partly due to perennial obstacles to implementing a national prevention and control progra...m.
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Rabies is a fatal zoonotic disease most often transmitted to people via bites from infected dogs. This course provides a general introduction to rabies, and the One Health approach currently taken to prevent it. It consists of seven video-lectures, demonstration videos, and lessons learnt from peopl...e who work at the frontline of rabies elimination programmes around the world. It targets both a general audience and those who would like to learn more about rabies and the pathway to eliminating this disease – like prospective and current public health and animal health practitioners in rabies endemic countries.
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‘World Rabies Day’ is observed worldwide to mark the death anniversary of Louis Pasteur, a
French biologist, microbiologist and chemist who developed the first rabies vaccine. It’s a day where
Anti Rabies actions are collated, intensified and showcased.