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Malaria Journal (2024) 23:255. Seasonal malaria chemoprevention (SMC) is a World Health Organization-recommended intervention for the prevention of malari
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a among children at high risk in areas with seasonal transmission. During the coronavirus disease 2019 (COVID-19) pandemic, SMC drug distribution was rapidly adapted to reduce contact and mitigate the risk of transmission between communities and community distributors, with caregivers administering doses.
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Rivercess, Liberia, April 25, 2024 - Liberia marks a monumental milestone in its battle against malaria
as it launches the highly anticipated RTS,S malar
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ia vaccine today, coinciding with World Malaria Day,
commemorated under the theme: Health Equity, Gender, and Human Rights: Accelerating the Fight
Against Malaria for a More Equitable World. The launch ceremony, held in Rivercess County, signals a
significant step forward in the nation's commitment to safeguarding the health of its children and
communities.
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We do not have to live in a world where 1,320 children die from a preventable disease every day
Integrated community case management (ICCM) – an approach where community-based health workers are trained to identify, treat and refer children under-five with pneumonia, diarrhoea and malaria
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is increasingly being used across sub-Saharan Africa to supplement the gaps in basic healthcare provision. ICCM programmes have been endorsed by major international organisations and donors, and many African Ministries of Health as a key strategy for reducing child mortality.
This learning paper describes Malaria Consortium’s approach to and experience of engaging local communities in integrated community case management (ICCM) in Uganda, Zambia and Mozambique.
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The webpage from Medicines for Malaria Venture (MMV) focuses on efforts to develop and provide child-friendly antimalarial treatments. It highlights the challenges of treating malaria
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in children, who are among the most vulnerable to the disease, and the need for safe, effective, and easy-to-administer formulations. MMV collaborates with global partners to ensure access to pediatric antimalarial medicines, such as dispersible tablets and rectal treatments, especially in low-resource settings. The page emphasizes the importance of innovation, accessibility, and partnerships in reducing childhood malaria mortality.
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The MalariaCare Toolkit. Tools for maintaining high-quality malaria
case management services.
Developed by MalariaCare, this module supports health supervisors in improving the management of sever
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e malaria by providing focused, case-based learning and mentorship. It provides clinical supervisors with the necessary tools to guide healthcare providers during outreach training and supportive supervision (OTSS) visits. The module is designed to strengthen diagnostic and treatment skills, particularly in areas that are often overlooked, such as severe malaria. It uses real-life case studies and guided discussions to assess and enhance clinical understanding. Its flexible structure can be adapted based on the knowledge level of the provider, promoting effective, practical learning in healthcare settings.
Accessed on 03/07/2025.
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The primary objectives of the 2017 TMIS are to measure the level of ownership and use of mosquito nets; assess coverage of intermittent preventive treatment for pregnant women; identify treatment practices, including the use of specific antimalarial medications to treat
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malaria among children age 6-59 months; measure the prevalence of malaria and anemia among children age 6-59 months; and assess knowledge, attitudes, and practices among adults with malaria.
This table provides estimates of key indicators for the country as a whole and for each of the 31 geographic regions in Tanzania. A comprehensive analysis of the 2017 TMIS data will be presented in a final report. more
This table provides estimates of key indicators for the country as a whole and for each of the 31 geographic regions in Tanzania. A comprehensive analysis of the 2017 TMIS data will be presented in a final report. more
Where malaria transmission is seasonal, notably in Africa’s Sahel region, children of all ages most at risk of severe
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malaria are protected through SMC. This intervention consists of full antimalarial treatment courses of sulfadoxine-pyrimethamine and amodiaquine (SPAQ), administered monthly (28 days) during the high-transmission period (typically the rainy season), generally for up to five months per year. SMC can be deployed relatively easily across a large population and is highly cost-effective at only USD $0.30-0.40/dose,3 making it an important tool for malaria control
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Every two minutes, a child under the age of 5 dies from malaria. Under-five children accounted for 67 per cent of all malaria deaths worldwide
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in 2018. Most of them occurred in sub-Saharan Africa where an estimated 24 million children were infected with its deadliest form. In addition to being the third-deadliest infectious disease for children, malaria infection and the costs of treatment traps families in a cycle of illness, suffering and poverty.This year’s World Malaria Day is marred by the emergence of the COVID-19 outbreak, which further threatens people’s lives and well-being. Public health officials are taking precautionary and often aggressive measures to limit transmission of this virus, including reductions in social movement, physical distancing, hand-washing and recommending the use of personal protection equipment in high-risk settings. However, while focusing on combating this disease, the world cannot afford to ignore other diseases, such as malaria.
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The WHO recommends parenteral artesunate over quinine and artemether for treating severe Plasmodium falciparum malaria in adults and children. Intr
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avenous administration is preferred. A new one-step, arginine-based formulation eliminates the need for dilution steps, reducing errors and accelerating the initiation of treatment—a critical factor for survival. This formulation was first prequalified by the WHO in 2023. By contrast, the conventional two-step artesunate formulation, which was prequalified in 2010, requires more complex preparation. Clear guidance is essential, as product-specific protocols differ. These training materials aim to support the correct and effective administration of the medication.
Accessed on 27/06/2025.
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This comic book is a children-friendly tool to support school safety, to raise awareness and protect communities against malaria. The comic is available i
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n English, Khmer, Lao, Burmese and Vietnamese
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The Malaria Partners International Webinar Series highlights the vital importance of education in the fight against malaria. The series provides a
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variety of educational resources, which have been created and curated by Malaria Partners International and its global partners. Key webinars address critical topics such as the intersection of malaria and climate change, the impact of the pandemic on malaria control efforts, and the challenges of protecting vulnerable groups such as children and pregnant women. The series also highlights advances in malaria diagnostics, using case studies such as the Ghana Microscopy Project, and provides foundational knowledge on malaria transmission and prevention. By fostering awareness and knowledge sharing, these webinars support global efforts towards malaria eradication.
Accessed on 01/07/2025.
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Poverty and associated health, nutrition, and social factors prevent at least 200 million children in developing countries from attaining their developmental potential. We review the evidence linkin
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g compromised development with modifiable biological and psychosocial risks encountered by children from birth to 5 years of age. We identify four key risk factors where the need for intervention is urgent: stunting, inadequate cognitive stimulation, iodine deficiency, and iron deficiency anaemia. The evidence is also sufficient to warrant interventions for malaria, intrauterine growth restriction, maternal depression, exposure to violence, and exposure to heavy metals. We discuss the research needed to clarify the effect of other potential risk factors on child development. The prevalence of the risk factors and their effect on development and human potential are substantial. Furthermore, risks often occur together or cumulatively, with concomitant increased adverse effects on the development of the world's poorest children.
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Malaria remains a significant global health concern, with 249 million cases and 408,000 deaths reported in 2022, primarily in sub-Saharan Africa. T
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he most vulnerable populations are children under five and pregnant women. Rapid and accurate diagnosis using microscopy or malaria rapid diagnostic tests (mRDTs) is essential to ensure timely treatment, prevent severe disease and promote the rational use of antimalarial drugs. This UNICEF Technical Bulletin provides guidance on the procurement, quality assurance and selection of WHO-prequalified mRDTs, including considerations for areas with a high prevalence of pfhrp2/3 gene deletions. The bulletin also highlights UNICEF’s approach to sustainability, product verification and long-term arrangements with manufacturers, which ensure a reliable supply while supporting integrated child health management programmes. The bulletin serves as a valuable resource for countries, partners and programmes involved in the implementation of malaria case management and diagnostics.
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In 2015, 5.9 million children under age five died (1). The major causes of child deaths globally are pneumonia, prematurity, intrapartum-related complications, neonatal sepsis, congenital anomalies,
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diarrhoea, injuries and malaria (2). Most of these diseases and conditions are at least partially caused by the environment. It was estimated in 2012 that 26% of childhood deaths and 25% of the total disease burden in children under five could be prevented through the reduction of environmental risks such as air pollution, unsafe water, sanitation and inadequate hygiene or chemicals.
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Two malaria vaccines are currently WHO prequalified and recommended1 for use to prevent
P. falciparum malaria in young
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children, the RTS,S/AS01 vaccine, currently manufactured by
GlaxoSmithKline (GSK), and the R21/Matrix-M vaccine, manufactured by Serum Institute of India
Pvt (SII)
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This guide provides practical tools and strategies for interpersonal communication (IPC) to support the prevention and treatment of malaria in northern Nigeria. Targeting health workers, community l
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eaders and vulnerable groups such as pregnant women and young children, it aims to improve knowledge, attitudes and behaviours through culturally appropriate, tailored messaging. The guide emphasises community engagement, effective counselling techniques, and collaboration with local stakeholders to improve malaria control.
Accessed on 20/06/2025.
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According to the WHO, there were an estimated 251 million malaria cases (95% of global cases) and 579,414 malaria deaths (97% of global deaths) in
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African Union Member States in 2023. 76% of these deaths were children under the age of five.
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The document “Malaria Prophylaxis for Travellers: Guideline for Healthcare Workers” (2019) from Sri Lanka provides guidance for healthcare providers on preventing malaria among travelers to ende
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mic areas.
It explains that since Sri Lanka was certified malaria-free in 2016, the main risk comes from imported cases, mostly Sri Lankan travelers. The document emphasizes assessing travelers’ risk, advising on mosquito bite prevention, and prescribing appropriate chemoprophylaxis like chloroquine, mefloquine, atovaquone-proguanil, or doxycycline depending on destination and traveler profile.
It highlights that children, pregnant women, and immunocompromised individuals are particularly at risk, and stresses adherence to medications and protective measures. Special instructions are given on handling missed doses, long-term prophylaxis, and managing side effects. Overall, the guideline aims to maintain Sri Lanka’s malaria-free status by preventing reintroduction through well-informed traveler care.
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Chemoprevention is the use of medicines, either alone or in combination, to prevent malaria infection and its consequences. This publication provides standardized approaches for monitoring and evalu
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ating the efficacy of medicines used for intermittent preventive treatment of malaria in pregnancy, perennial malaria chemoprevention (formerly known as intermittent preventive treatment of malaria in infants), seasonal malaria chemoprevention and intermittent preventive treatment of malaria in school-aged children. It follows the recent release of new and updated WHO recommendations on these interventions.
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