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Lenacapavir-associated drug resistance: implications for scaling up long-acting PrEP
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex F
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In-depth: What should behaviour change efforts look like in the PrEP era?

Molelekwa, T. Spotlight (2022) CC
what lessons can we take from the last few decades of health behaviour change efforts as we enter the era of HIV prevention pills, rings and injections?
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Systematic review of values and preferences for lenacapavir as pre-exposure prophylaxis and other forms of long-acting injectable PrEP
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex C
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Should HIV testing services with rapid diagnostic tests and/or self-tests be used for initiation or continuation of injectable long-acting PrEP?
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex D
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AI and HIV Programs: A guide for advocates

PrEP Watch (2025) CC
This brief from Audere and AVAC explains how artificial intelligence (AI) can support the HIV field by expanding reach, enhancing prevention, and improving care.
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HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis

World Health Organization WHO (2020) C_WHO
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely ... more
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Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis
recommended

World Health Organization WHO (2025) C_WHO
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as it allows people to choose a method that ... more
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Differentiated and simplified pre-exposure prophylaxis for HIV prevention: update to WHO implementation guidance

World Health Organization WHO (2022) C_WHO
This technical brief aims to support these trends, accelerated by the COVID-19 pandemic, and improve PrEP uptake, persistence, and effective use by providing implementation guidance for differentiated and simplified service delivery. The brief aims ... more
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Guidelines on long-acting injectable cabotegravir for HIV prevention
recommended

World Health Organization WHO (2022) C_WHO
In this guideline, WHO recommends that long-acting injectable cabotegravir (CAB-LA) may be offered as an additional HIV prevention option for people at substantial risk of HIV infection. CAB-LA is an injectable form of pre-exposure prophylaxis (PrEP ... more