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This information leaflet is for general informative purposes only. It can be used in its current form or further modified and adapted by responsible authorities in each country as a country-specific guidance.
Antimicrobial Resistance and Infection Control 2014,3 :31
Hindawi Publishing Corporation
Tuberculosis Research and Treatment
Volume 2015, Article ID 752709, 7 pages
NOVEMBER 2012
This document serves as an update to “Out of the Dark”, a report published by MSF in October 2011, highlighting the need to prioritise the long-neglected area of paediatric tuberculosis (TB). This update will outline the key improvements and setbacks—the ‘highlights’ and ‘
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PLOS ONE | DOI:10.1371/journal.pone.0142290 November 9, 2015; 1 / 16
treat TB
Description of Research Outputs, 2009 - 2014
Year one report
INITIATIVE «ALL IN» EN RDC, Rapport Phase 1
In case of resistance to rifampicin, fluoroquinolones become the preferred category of second-line drugs. Unfortunately, quinolone-resistant strains of Mycobacterium leprae have also been reported in several countries, probably due to the extensive use of quinolones for treating several types of inf
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ections. Clofazimine resistance is still rare but this antimicrobial cannot be given alone
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upply essential data, and to fill the gaps in humanitarian response that cause this exclusion.
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High levels of storage iron may increase malaria susceptibility. This risk has not been investigated in semi-immune adolescents. We investigated whether baseline iron status of nonpregnant adolescent girls living in a high malaria transmission area in Burkina Faso affected malaria risk during the fo
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llowing rainy season. For this prospective study, we analysed data from an interim safety survey, conducted six months into a randomised iron supplementation trial. We used logistic regression to model the risk of P. falciparum infection prevalence by microscopy, the pre-specified interim safety outcome, in relation to iron status, nutritional indicators and menarche assessed at recruitment.
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