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1
Historically, the discovery of the sulfa drugs in the 1930s and the subsequent development of penicillin during World War II ushered in a new era in the treatment of infectious diseases. Infections that
...
were common causes of death and disease in the pre-antibiotic era - rheumatic fever, syphilis, cellulitis and bacterial pneumonia - became treatable, and over the next 20 years most of the classes of antibiotics that find clinical use today were discovered and changed medicine in a profound way. The availability of antibiotics enabled revolutionary medical interventions such as cancer chemotherapy, organ transplants and essentially all major invasive surgeries from joint replacements to coronary bypass. Antibiotics, though, are unique among drugs in that their use precipitates their obsolescence. Paradoxically, these cures select for organisms that can evade them, fueling an arms race between microbes, clinicians and drug discoverers.
Wright BMC Biology 2010, 8:123 http://www.biomedcentral.com/1741-7007/8/12
more
This report assesses the impact of the conflict in Ukraine and its implications for organized crime and security-related issues for neighbouring countries, with a focus on Moldova.
These include:
...
Organized crime and illicit trafficking (including trafficking in persons, drugs, arms, illicit tobacco, and other goods); Cybercrimes and fraud; Disinformation and propaganda; and Chemical, Biological, Radiological, and Nuclear (CBRN) threats.
more
The current document is anupdate of the guidelines developed by the EUCAST subcommittee on detection of resistance mechanisms. The EUCAST Steering Committee has carried out the current update. The document has been developed mainly for routine use in clinical laboratories
...
and doesnot cover technical procedures for identification of resistance mechanisms at a molecular level by reference or expert laboratories. However, much of the content is also applicable tonational reference laboratories. Furthermore, it is important to note that the document does not cover screening for asymptomatic carriage (colonization) of multidrug-resistant microorganismsor direct detectionof resistancein clinical samples.
more
Discussions about climate change often focus on the future, but millions of children are experiencing its devastating impacts now. The scale of the crisis is huge, and growing fast. It is children that will bear the brunt of climate change, yet its
...
impact on them is understudied, their voices are not being heard, and current solutions are woefully inadequate. It is a perfect storm that we must stop in its path – before it is too late.
Available in English, French, Spanish, Portuguese, Arabic
more
These draft guidelines are designed to encourage humanitarian and development non-governmental organisation (NGO) practitioners to think about the types of scientific information and expertise they
...
may need, how to access and use them, and how to ensure that they are applied in an ethical and accountable manner. The publication addresses the need to defines the problem and the purpose of integrating science with the users of science, issues around access to science and understanding scientific information, how to apply the science and the important of monitoring and evaluation of impact. Case studies include a project from Christian Aid and the Evangelical Association of Malawi which brought together community members from Village Civil Protection Committees with scientists from the Department of Climate Change and Meteorology and District Council staff responsible for water management and disaster risk reduction in order to tackle a problem of flooding
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This brief highlights the urgency of addressing gender inequalities across the Rio Conventions, provides examples of where progress has been made, and identifies clear entry points for addressing gender equality considerations across the Conventions
...
. It makes recommendations for actions to accelerate the synergistic implementation of the gender provisions and action plans of the Conventions.
more
The Minimum Standards for Age and Disability Inclusion in Humanitarian Action inform the design, implementation, monitoring and evaluation of humanitarian programmes across all sectors
...
and phases of response, and in all emergency contexts, ensuring older people and people with disabilities are not excluded.
more
This manual aims to provide practical guidance to field workers in order to maximise the nutritional impact of food security & livelihoods (FSL) interventions. This requires the systematic use of a ‘nutrition lens’ at each step of the project cycle and
...
a close collaboration between sectors.
more
Integrated Water Resources Management in Myanmar: Water usage and introduction to water quality criteria for lakes and rivers in Myanmar. Preliminary report
Mjelde, Marit; Ballot, Andreas; Swe, Thida; Eriksen, Tor Erik; Nesheim, Ingrid; Aung, Toe Toe
Norsk institutt for vannforskning (NIVA)
(2017)
C1
The purpose of the report is to present some first recommendation for the development of Myanmar ecological quality criteria using the system of the EU Water Framework Directive (EU WFD) as baseline, with main focus on the characterization and class
...
ification processes. As background for the recommendations we first give an overview of the main water use categories in Myanmar. We then provide preliminary suggestions for typology criteria and indices for assessing ecological status in lakes and rivers in Myanmar. The typology factors and physico-chemical parameters are based on common used factors in the EU countries. The biological elements include phytoplankton and aquatic macrophytes for lakes, and benthic invertebrates for rivers.
more
The Central African Republic is at a major turning point in its history. The country
is just emerging from a very violent conflict, during which thousands of human lives were lost and one-third of the population was displaced. After
a three-year t
...
ransition, and with the support of the international community, authorities successfully created the conditions required to conduct credible presidential and legislative
elections. Central African citizens mobilized to express their desire for peace and to break
with the cycle of past violence. Their exemplary democratic maturity ensured the electoral
process was peaceful, despite palpable tensions. The welcome given Pope Francis in Bangui in
November 2015 and visible reconciliation efforts demonstrate the population wishes to turn
the page on this conflict.
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