N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535
Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)
This topic last updated: Apr 28, 2020.
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A Systematic Review and Meta-analysis
Clinical Infectious Diseases® 2016;62(12):1586–94
2nd edition. The 2018 Roadmap incorporates an additional critical population: adolescents. Despite making up 1 in 6 of the world’s people, adolescents have been largely overlooked as global momentum to address TB has grown. Spanning the ages of 10–19 years, adolescents are both at risk of TB and... represent an important population for TB control. They often present with infectious TB and frequently have multiple contacts in congregate settings, such as schools and other educational institutions. Nevertheless, few countries capture TB data in suitably age-disaggregated ways to allow full understanding of its impact in this group and even fewer provide the adolescent-friendly services our young people need to access diagnosis and care.
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Naicker et al. BMC Palliative Care (2016) 15:41 DOI 10.1186/s12904-016-0114-7
These guidelines provide updated evidence-based recommendations on the priority HCV-related topics from the 2018 WHO Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C infection and the 2017 WHO Guidelines on hepatitis B and C testing. These priority areas are:
... direct-acting antiviral (DAA) treatment of adolescents and children ages ≥3 years of age
simplified HCV service delivery (decentralization, integration and task sharing)
HCV diagnostics – use of point-of-care (POC) HCV ribonucleic acid (RNA) assays and reflex HCV RNA testing.
These guidelines also update existing chapters without new recommendations, such as the inclusion of new manufacturers’ protocols on the use of dried blood spot (DBS) for HCV RNA testing and new data to inform the limit of detection for HCV RNA assays as a test of cure, in addition to their use for diagnosis.
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Provide guidance to HIV care practitioners on the optimal use of antiretroviral (ARV) agents for the treatment of HIV infection in adults and adolescents.
The report presents successful case studies from around the world, including the implementation of minimum protection standards for refugee children in Germany, cross border child protection systems in West Africa, and finding alternatives to the detention of migrant children in Zambia. Other countr...ies featured in the report include Afghanistan, Italy, Jordan, Lebanon, South Sudan, Vietnam, Uganda and the U.S. Each of the initiatives can be replicated in different contexts and inform child-focused actions and policy change at national, regional and global levels to be agreed in the framework of the Compact.
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Other disorders
Chapter H.5.1
These new reports from WHO document evidence of widespread inappropriate promotion of baby and toddler foods. Despite the WHO Guidance on ending inappropriate promotion of foods for infants and young children agreed in 2016 and nearly 40 years since the introduction of the International Code of Mark...eting of Breast-milk Substitutes, many companies that manufacture or distribute commercial baby foods fail to comply with these rules.
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A 2013 Plan study across 30 countries found that children with disabilities were on average 10 times less likely to go to school than children without disabilities. This report presents the findings of a follow-up second phase to the research with a qualitative study on barriers and enablers to educ...ation for children with disabilities in Nepal.
The Full Report and Executive Summary Reports in English, French and Spanish are now available for download at:
http://disabilitycentre.lshtm.ac.uk/include-us-education-study-available-now/
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This study explored family adjustment and access to rehabilitative services for children with Down syndrome, between 0-5 years of age, in the ecoculture of Petchaburi Province, Thailand.
Part of the CBM Prevention Toolkit on Cerebral Palsy. | This manual is meant to be used in combination with the Flipcharts on Cerebral Palsy developed by CBM and CCBRT (Tanzania). The full Prevention Toolkit on Cerebral Palsy (composed of the A4 Flipcharts, this Manual and a Fact sheet) aims to miti...gate the disabling effects of cerebral palsy through improved new born care and greater community awareness.
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This Ebola Poster with its 20 Messages was developed with people working with children in schools in Sierra Leone during the Ebola crisis in 2014. It has been adapted in 2018. CfH has 100 other messages for children to learn and share in 10 health topics
PLOS ONE | https://doi.org/10.1371/journal.pone.0210937
February 5, 2019