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Handbook on TB laboratory diagnostic methods in the European Union

European Centre for Disease Prevention and Control (2016) C1

The aim of this handbook is to provide network members and other laboratories involved in the diagnosis of tuberculosis, with an agreed list of key diagnostic methods and their protocols in various areas of TB diagnosis, ranging from microbiological diagnosis of active TB to the diagnosis of latent ... more

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Antimicrobials use, reistance and containment baseline survey (Ethiopia)

Drug Administration and Control Authority of Ethiopia , et al. (2009) C1

Emergence of antimicrobial resistance is a result of the use, overuse and misuse of antibiotics both in humans and animals. In Ethiopia, there are indications on the misuse of antibiotics by health care providers’, unskilled practitioners, and drug consumers. These coupled with rapid spread of res... more

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Self-Study Modules on Tuberculosis

Centers for Disease Control and Prevention CDC (2014) C_CDC

The CDC Self-Study Modules on Tuberculosis are a series of nine educational modules divided into two courses. The first course (Modules 1–5) provides fundamental information about tuberculosis, while the second course (Modules 6–9) offers more specific program-related details. These modules are ... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Faith sector response to hiv and aids in kenya action plan 2015/2016-2019/2020

Ministry of Health, Kenya; National AIDS Control Council (2015) C1

The National AIDS Control Council (NACC) continues to strengthen partnerships with all stakeholders in the response to HIV and AIDS in Kenya. While recognizing that there is no single preventive approach to reverse the spread of HIV, the faith sector comprising of Faith Communities (FCs) a... more

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A guide for surveillance of antimicrobial resistance in leprosy: 2017 update
recommended

E. A. Cooreman WHO SEARODepartment of Control of Neglected Tropical Diseases (2017) C_WHO

In case of resistance to rifampicin, fluoroquinolones become the preferred category of second-line drugs. Unfortunately, quinolone-resistant strains of Mycobacterium leprae have also been reported in several countries, probably due to the extensive use of quinolones for treating several types of inf... more

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American Trypanosomiasis (also known as Chagas Disease)

Centers for Disease Control and Prevention CDC (2022) C_CDC

Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where pover... more

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Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1

Limited coverage of laboratory services and long turnaround times from real-time reverse transcription-polymerase chain reaction (rRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been insufficient to meet the demands in many African countries in response... more

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Zika virus and safety of substances of human origin – A guide for preparedness activities in Europe

European Centre for Disease Prevention and Control (2016) CC

The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.

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Occupational exposures to Ebola virus in Ebola treatment center, Conakry, Guinea

Savini H, Janvier F, Karkowski L, et al. Centers for Disease Control and Prevention (2017) C_CDC

Emerg Infect Dis. 2017 Aug (Accessed July 18,2017) Abstract: We report 77 cases of occupational exposures for 57 healthcare workers at the Ebola Treatment Center in Conakry, Guinea, during the Ebola virus disease outbreak in 2014-2015. Despite the high incidence of 3.5 occupational exposures/healt... more

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Guidelines for Handling Decedents Contaminated with Radioactive Materials

Wood MC, DePaolo, F, Whitaker RD Centers for Disease Control and Prevention (CDC) (2007) C_CDC

Detonation of a nuclear weapon or activation of a radiological dispersal device could cause radioactively contaminated decedents. These guidelines are designed to address both of these scenarios. They could also be applicable in other instances where decedents’ bodies are contaminated with radioa... more

Non-communicable diseases, injuries, and mental ill-health in Africa: the role of the Africa CDC

Africa Center for Disease Control and Prevention CDC (2022) C_CDC

The Africa Centres for Disease Control and Prevention (Africa CDC) was established in 2017, after the west Africa Ebola virus disease outbreak. Upon creation, the role of Africa CDC was to mandate strengthening of the capacity of public health institutions in Africa to prevent, detect, and respond ... more

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Implications of the Marburg virus disease outbreak in Rwanda for the EU/EEA, 2024

European Centre for Disease Prevention and Control (ecdc) (2024) C_CDC

This threat assessment addresses the implications of the ongoing Marburg virus disease (MVD) outbreak in Rwanda for the European Union/European Economic Area (EU/EEA). MVD is a severe disease in humans and, although uncommon, it has the potential to cause epidemics with significant case fatality. ... more

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Considerations for the use of face masks in the community in the context of the SARS-CoV-2 Omicron variant of concern

European Centre for Disease Prevention and Control ECDC (2022) CC

Wearing a face mask can help reduce the spread of COVID-19 in the community by reducing the release of respiratory droplets from asymptomatic / pre-symptomatic individuals or those with mild non-specific symptoms. The use of face masks for this purpose may be adopted to reduce the societal impact as... more

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Тестування на туберкульозну інфекцію та скринінг на туберкульоз серед біженців, які прибувають до країн Європи з України

European Centre for Disease Prevention and Control ECDC (2022) C1

7 April 2022. Aimed at national policymakers, public health and healthcare planners, staff working in reception centres, and healthcare staff caring for displaced persons, the information note concludes that universal testing of incoming refugees from Ukraine for tuberculosis (TB) infection is not r... more

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Antibiotic resistance: How does antibiotic resistance spread?

European Centre for Disease Prevention and Control (2014) C2

Antibiotic resistance is a natural occurrence caused by mutations in bacteria’s genes. However, inappropriate use of antibiotics accelerates the emergence and spread of antibiotic-resistant bacteria. When exposed to antibiotics, susceptible bacteria are killed; while excessive antibiotic use or th... more

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Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version)
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

إرشاداتٌ حول إنشاء عنابر العزل الخاصة بالحالات المصابة بفيروس كورونا المستجد This document simplifies the WHO guidance on severe acute respiratory infection (SARI) treatment centres and is meant to be accessible to healthcare work... more

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Covid-19 Test to Treat Guidelines
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

n response to the outbreak, the Africa Centres for Disease Control and Prevention (Africa CDC) has been supporting African Union Member States in responding to the COVID-19 pandemic through a variety of interventions such as non-pharmaceutical interventions, quarantine, testing, isolation, contact t... more

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Action Protocol for Enhanced SARI and ILI Surveillance for COVID-19 in Africa (Arabic)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C2

March 2020 The number of African Union Member States reporting COVID- 19 cases is increasing and there is a likelihood of community transmission. The WHO recently modified the COVID-19 suspect case definition to include severe acute respiratory infection and advises testing of all severe acute r... more

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West Africa - Ebola Outbreak, Fact Sheet #39, Fiscal Year (FY) 2015 (as of July 14, 2015)

US Agency for International Development, Centers for Disease Control and Prevention (2015)

The Government of Liberia (GoL) reports three additional EVD cases linked to the Margibi County cluster, including one in Liberia’s Montserrado County; new confirmed case total reaches six Recently extended Operation Northern Push strengthens contact tracing and EVD prevention activities ... more

A guide for surveillance of antimicrobial resistance in leprosy: 2017 update recommended

Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa recommended

Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version) recommended

Covid-19 Test to Treat Guidelines recommended

A guide for surveillance of antimicrobial resistance in leprosy: 2017 update
recommended

Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa
recommended

Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version)
recommended

Covid-19 Test to Treat Guidelines
recommended