Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ...serious adverse events (SAEs).
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The purpose of this guidance is to provide emergency planners with nuclear detonationspecific
response recommendations to maximize the preservation of life in the event of
an urban nuclear detonation. This guidance addresses the unique effects and impacts of a
nuclear detonation such as scale of ...destruction, shelter and evacuation strategies,
unparalleled medical demands, management of nuclear casualties, and radiation dose
management concepts.
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Further analysis of the Nepal Demographic and Health Surveys, 2001-2011
Acute Radiation Syndrome (ARS) (sometimes known as radiation
toxicity or radiation sickness) is an acute illness caused by
irradiation of the entire body (or most of the body) by a high dose
of penetrating radiation in a very short period of time (usually ... a
matter of minutes). The major cause of this syndrome is depletion
of immature parenchymal stem cells in specific tissues. Examples of
people who suffered from ARS are the survivors of the Hiroshima
and Nagasaki atomic bombs, the firefighters that first responded
after the Chernobyl Nuclear Power Plant event in 1986, and some
unintentional exposures to sterilization irradiators.
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PERC produces regional and member state situation analyses, updated regularly.
PlosOne Published: July 14, 2021
https://doi.org/10.1371/journal.pone.0254339
MMWR Morbidity and Mortality Weekly Report December 19, 2014 / 63(50);1205-1206
The international community sits at the tipping pointof a post-‐antibiotic era, where common bacterial infections are no longer treatable with the antibiotic armamentarium that exists. In South Africa, t...he identification of the first case of pan-‐resistant Klebsiella pneumoniae(Brink et al, J Clin Microbiol. 2013;51(1):369-‐72) marks a watershed moment and highlights ourtip of the antibiotic resistance ‘iceberg’ in this country. Multi-‐drug resistant (MDR)-‐bacterial infections, predominantly in Gram-‐negative bacteria such as Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosaand Acinetobacter baumanniiare now commonplace in South African hospitals. Whilst a number of expensive new antibiotics for Gram-‐positive bacterial infections have been manufactured recently (some of which are licenced for usein South Africa), no new antibiotics active against Gram-‐negative infections are expected in the next 10-‐15years. Hence what we have now, needs conserving
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The information provided here can be used to understand the current situation, increase attention to preterm births in Rwanda and to inform dialogue and action among stakeholders. Data can be used to identify the most important risk factors to target and gaps in care in order to identify and impleme...nt solutions for improved outcomes.
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BMJ 2020;368:m800 doi: 10.1136/bmj.m800 (Published 5 March 2020)
Cholera is a diarrhoeal disease that is usually contracted when drinking water contaminated with Vibrio cholerae bacteria. The fight against this disease requires a multidisciplinary approach that combines a water, hygiene and sanitation (WaSH) response with a monitoring system, improved water suppl...y and quality, sanitation and hygiene, and a health response with the treatment of the disease itself.
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Annex to Selection and use of Ebola in vitro diagnostic assays
Journal of The Association of Physicians of India, Vol. 63 November 2015,, pp.77-96
The reports bring together the latest findings and conclusions about the state of resistance to artemisinins and artemisinin-based combination therapy (ACT), summarize WHO’s current policy and treatment recommendations, and highlight areas of concern.