Dengue is a mosquito-borne viral disease that occurs mainly in the tropics and subtropics but has a high potential to spread to new areas. Dengue infections are climate sensitive, so it is important to better understand how changing climate factors affect the potential for geographic spread and futu...re dengue epidemics. Vectorial capacity (VC) describes a vector's propensity to transmit dengue taking into account human, virus, and vector interactions. VC is highly temperature dependent, but most dengue models only take mean temperature values into account. Recent evidence shows that diurnal temperature range (DTR) plays an important role in influencing the behavior of the primary dengue vector Aedes aegypti. In this study, we used relative VC to estimate dengue epidemic potential (DEP) based on the temperature and DTR dependence of the parameters of A. aegypti. We found a strong temperature dependence of DEP; it peaked at a mean temperature of 29.3°C when DTR was 0°C and at 20°C when DTR was 20°C. Increasing average temperatures up to 29°C led to an increased DEP, but temperatures above 29°C reduced DEP. In tropical areas where the mean temperatures are close to 29°C, a small DTR increased DEP while a large DTR reduced it. In cold to temperate or extremely hot climates where the mean temperatures are far from 29°C, increasing DTR was associated with increasing DEP. Incorporating these findings using historical and predicted temperature and DTR over a two hundred year period (1901-2099), we found an increasing trend of global DEP in temperate regions. Small increases in DEP were observed over the last 100 years and large increases are expected by the end of this century in temperate Northern Hemisphere regions using climate change projections. These findings illustrate the importance of including DTR when mapping DEP based on VC.
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The impact of maternal mental health problems on infants in high income countries has been identified mostly in terms of psychosocial and emotional development, thanks to the groundbreaking early work of Spitz (2) and of Bowlby (3), who studied the emotional needs of infants and mother-child attachm...ent. Subsequently, a large body of literature, also from HICs, documented the effects of maternal mental health on the child's psychological development (4), intellectual competence(5), psychosocial functioning (6) and rate of psychiatric morbidity (7, 8).
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El coronavirus se está extendiendo a nivel mundial. ¿Cómo pueden los individuos, las comunidades y los actores humanitarios responder mejor al brote de COVID-19? ¿Cómo puede el Manual Esfera orientar nuestra respuesta?
Este documento tiene dos secciones: A. La primera sección aborda los... principios fundamentales que son esenciales para conseguir una intervención exitosa y holística. B. La segunda aborda las normas y la orientación relevantes en los capítulos en materia de WASH y Salud del Manual Esfera.
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This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex...t part of the vaccine journey: the steps from completing the clinical trial phases through to distribution
Available in English, French, Spanish, Arabic, Chinese and Russian
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Global UNIDO Project: Strengthening the local production of essential generic drugs in the least developed and developing countries
GUIDELINES FOR AWWs/ASHAs/ANMs/PRIs
В настоящем документе проводится анализ международного права по проблематике прав человека с целью обеспечить законодателей, разработчиков политики, специалист...в, работающих в сфере охраны психического здоровья, и активистов неправительственных организаций информацией об обязанностях государств, которые должны быть отражены во внутреннем законодательстве по охране психического здоровья и правам инвалидов. В документе рассматриваются некоторые важнейшие права, базирующиеся на конвенциях, и стандарты Организации Объединенных Наций по правам человека, такие как Принципы ПБ и Стандартные правила. В документе показано, как эти стандарты можно использовать в качестве руководства по обеспечению соблюдения требований международных конвенций о правах человека.
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In this article a cluster randomized cross-sectional survey, conducted in Albay Province in the Philippines in April 2016, was used to assess the prevalence of disability and access to support services. This was done with the purpose of generating representative data for local programme development.... A cross-sectional survey was carried out with the WG/UNICEF methodology to examine the prevalence of disabilities, and the accessibility and coverage of relevant services. The aim is for this information to be used for public policy formulation at all levels, as well as to improve communication and advocacy on disabilities.
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