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The Lancet Volume 5, Issue 10100972October 2024 Chagas Disease Serie 3
The Lancet Microbe Series Chagas Disease 2 Volume 5, Issue 10100946 October 2024
While motivational factors vary, opportunities for career advancement, stimulating and challenging tasks, opportunities for promotion, and co-worker recognition are core factors that can engender retention of rural health workers. Interventions are required to enhance rural health worker motivation
...
and retention, including strengthening the supervision system, developing career progression pathways, and ensuring clear and transparent incentives. Strategies around retention need to be addressed as these would better enable rural primary health workers to cope with the challenging conditions they work in rural areas.
more
Journal of Computational Biophysics and ChemistryVol. 22, No. 01, pp. 31-41 (2023)
Buruli ulcer (BU), a neglected tropical disease (NTD), is an infection of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. The disease has been documented in many South American, Asian, and Western Pacific countries and is widespread throughout much of Africa, especially in West
...
and Central Africa.
more
Insufficient funding is hindering the achievement of malaria elimination targets in Africa, despite the pressing need for increased investment in malaria control. While Western donors attribute their inaction to financial constraints, the global health community has limited knowledge of China’s ex
...
panding role in malaria prevention. This knowledge gap arises from the fact that China does not consistently report its foreign development assistance activities to established aid transparency initiatives. Our work focuses on identifying Chinese-funded malaria control projects throughout Africa and linking them to official data on malaria prevalence. By doing so, we aim to shed light on China’s contributions to malaria control efforts, analysing their investments and assessing their impact. This would provide valuable insights into the development of effective financing mechanisms for future malaria control in Africa.
more
The Plan subscribes to the goals and pillars of the WHO Global Technical Strategy against Malaria 2016-2030 (GTS), while presenting key elements to address the specific challenges of the Region.
Mozambique was the first country outside of the Sahel to successfully implement seasonal malaria chemoprevention (SMC) on a large scale. This learning paper captures some of the lessons drawn from the implementation process.
The presentation titled "Malaria Capacity Building Initiative" outlines efforts led by the WHO and partner organizations to strengthen the skills and systems needed to fight malaria globally. It highlights the need for a coordinated, long-term strategy to build human resource capacity in malaria-end
...
emic countries—especially among national malaria control programs, frontline health workers, NGOs, and WHO staff. The document reviews past and current training activities, such as workshops on case management, entomology, vector control, epidemiology, and planning. It emphasizes the development of standardized training materials and competency frameworks, the role of national and regional training centers, and the use of blended learning methods (e.g., e-learning and in-person sessions). The goal is not just to deliver training, but to build sustainable capacity through partnerships, continuous improvement, quality assurance, and integration into health systems. It also calls for better coordination, tracking of trained personnel, and engagement of ministries of finance to ensure long-term support.
more
Clinical Pharmacology: Advances and Applications, 2025:17 29–47
The WHO susceptibility test kit has been extensively used for monitoring of insecticide resistance in disease vectors for many years. Over the years, users have reported issues with these kits and potential improvements to WHO in an ad-hoc manner. To systematically determine whether the reported iss
...
ues were widespread and to collate potential improvements to the kit, a survey of users was put online from 30 June to 15 October 2023. The results from this survey are reported in this report.
more
In recent decades we have seen progressive changes to global climate patterns caused by anthropogenic impacts on the environment. These are likely to directly and indirectly affect human health, and are projected to continue and potentially
accelerate into the future. Neglected tropical diseases (N
...
TDs) and malaria are potentially particularly sensitive to these changes as they
are prevalent amongst vulnerable populations
in countries expected to experience the greatest
environmental change in the coming decade.
more
Thematic brief. This brief highlights the link between climate change and VBDs in Asia Pacific. Using malaria to tell the narrative, it lists key actions that policymakers and the public health community can consider in addressing the impact of a changing climate on health. The brief also includes
...
a list of resources that countries can benefit from in planning their response.
more
The framework recommends expanded coverage of malaria diagnostic and treatment services, intensified vector control to drive down transmission, strengthened malaria surveillance, and increased transborder collaboration, especially in terms of efforts to control the sale and use of artemisinin monoth
...
erapies. Since it is unlikely that national malaria control programs will be able to implement all the activities described in this framework simultaneously, a list of suggested priority activities has been included in the Annex.
more
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex C
The National Strategic Plan on Malaria Prevention and Elimination Period 2021 – 2025 seeks to build on the previous national successes of the National Institute of Malariology, Parasitology, and Entomology (NIMPE) while addressing current challenges to reduce the overall burden of malaria in the S
...
outhern and Central provinces and to initiate elimination activities in remaining focal areas of transmission throughout the country. The overall targets proposed to be reached by 2025 are:
Reduce malaria morbidity rate to below 0.015/1,000 population
Reduce malaria mortality rate to below 0.002/100,000 population
Eliminate malaria in 55 provinces
Ensure no malaria outbreaks
To address the urgent threat of drug resistance, Viet Nam has committed to accelerate efforts to eliminate locally-acquired P. falciparum by 2023.
more
Integrated Outbreak Analytics (IOA) applies a multidisciplinary approach to understanding outbreak dynamics and to inform outbreak response. It aims to drive comprehensive, accountable, and effective public health and clinical strategies by enabling communities, and national and subnational health a
...
uthorities to use data for operational decision-making. IOA embraces a holistic perspective of outbreak dynamics throughout: from the trigger questions to the data that are collected or accessed, to the interpretation of results and the recommendations that follow. In addition, IOA promotes co-development and monitoring of evidence informed actions.
The IOA toolkit aims to provide a clear understanding of IOA and highlight the importance of using an integrated, holistic approach to manage outbreak responses. It provides step-by-step guidance for setting up IOA and putting IOA principles into action. Finally, this toolkit provides guidance on applying IOA in humanitarian and emergency contexts, offering a practical and adaptable approach to informing public health emergency responses.
Developed based on the model from the Democratic Republic of the Congo (DRC), its creation involved extensive consultation with experts experienced in IOA applications. The toolkit was piloted in Tanganyika Province, DRC, as well as Somalia and Sudan, demonstrating its adaptability to diverse emergency scenarios. It builds upon an existing array of tools, templates, reports, case studies, animations, and publications used by stakeholders in diverse contexts.
more
The 2022 report reviews the global malaria diagnostics market and technological landscape to support Unitaid’s 2023–2027 strategy for quality malaria case management. The report highlights the stalled progress of malaria control efforts, the gaps in access to diagnostics and the public health im
...
plications of P. falciparum HRP2/3 gene deletions, which compromise the accuracy of the widely used HRP2-detecting rapid diagnostic tests (RDTs). The report analyses the malaria RDT market, noting supplier diversification, price trends and production shifts resulting from the pandemic. It also addresses the emerging point-of-care G6PD testing market, which is required to ensure the safe radical cure of P. vivax infections. It surveys technological innovation, including digital microscopy, hemozoin tests, nucleic acid detection and biosensors, while emphasising that RDTs and microscopy will remain the mainstay of case management in the near term. The report identifies market shortcomings, access barriers and opportunities to improve malaria case management and diagnostic coverage.
more
This report synthesizes the state of knowledge on the interlinkages between environmental degradation climate change conflict and mobility in the East and Horn of Africa, focusing on Burundi, Djibouti, Ethiopia, Kenya, Somalia, South Sudan, Tanzania, and Uganda.
This document outlines the plan for a continental cholera prevention and control with the implementation framework for the Cholera IMST, detailing its governance structure, strategic priorities, and operational modalities
